SSRP1

 

Full name: structure specific recognition protein 1 Alias Symbol: FACT80
Type: protein-coding gene Cytoband: 11q12.1
Entrez ID: 6749 HGNC ID: HGNC:11327 Ensembl Gene: ENSG00000149136 OMIM ID: 604328
Drug and gene relationship at DGIdb

 

Expression of SSRP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SSRP1 6749 200957_s_at 0.4913 0.0869
GSE20347 SSRP1 6749 200957_s_at 0.8340 0.0000
GSE23400 SSRP1 6749 200957_s_at 0.7017 0.0000
GSE26886 SSRP1 6749 200957_s_at 0.9145 0.0001
GSE29001 SSRP1 6749 200957_s_at 0.5699 0.0842
GSE38129 SSRP1 6749 200957_s_at 0.7165 0.0000
GSE45670 SSRP1 6749 200957_s_at 0.3614 0.0053
GSE53622 SSRP1 6749 3000 0.4933 0.0000
GSE53624 SSRP1 6749 3000 0.7116 0.0000
GSE63941 SSRP1 6749 200956_s_at 1.2888 0.0135
GSE77861 SSRP1 6749 200957_s_at 0.8316 0.0007
GSE97050 SSRP1 6749 A_23_P36076 0.1640 0.6045
SRP007169 SSRP1 6749 RNAseq 1.5260 0.0003
SRP008496 SSRP1 6749 RNAseq 1.2071 0.0000
SRP064894 SSRP1 6749 RNAseq 0.4757 0.0011
SRP133303 SSRP1 6749 RNAseq 0.6302 0.0001
SRP159526 SSRP1 6749 RNAseq 0.8418 0.0002
SRP193095 SSRP1 6749 RNAseq 0.5795 0.0000
SRP219564 SSRP1 6749 RNAseq 0.4770 0.0772
TCGA SSRP1 6749 RNAseq 0.1784 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by SSRP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SSRP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SSRP1 6749 2 3 25
GSE20123 SSRP1 6749 2 3 25
GSE43470 SSRP1 6749 1 5 37
GSE46452 SSRP1 6749 9 4 46
GSE47630 SSRP1 6749 3 9 28
GSE54993 SSRP1 6749 3 0 67
GSE54994 SSRP1 6749 5 6 42
GSE60625 SSRP1 6749 0 3 8
GSE74703 SSRP1 6749 1 3 32
GSE74704 SSRP1 6749 2 3 15
TCGA SSRP1 6749 14 10 72

Total number of gains: 42; Total number of losses: 49; Total Number of normals: 397.  

 

Somatic mutations of SSRP1:

 

Generating mutation plots.

 

Highly correlated genes for SSRP1:

 

Showing top 20/2125 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SSRP1FYN0.823053303
SSRP1ZFHX30.812618303
SSRP1MCM70.80445111011
SSRP1ISY10.783704303
SSRP1INTS100.771641303
SSRP1EBNA1BP20.767207303
SSRP1PPIL10.766569707
SSRP1ILF20.76197611011
SSRP1ZNF7070.7548303
SSRP1KTI120.754721303
SSRP1AURKB0.75459111011
SSRP1SPTBN10.753248303
SSRP1MCM60.75295412011
SSRP1RIOK10.752236707
SSRP1CAD0.75220512012
SSRP1NCAPG20.75194310010
SSRP1STARD70.75160911010
SSRP1DTYMK0.75134211010
SSRP1CDT10.74922912012
SSRP1DNMT10.74907512012

For details and further investigation, click here