| Full name: glycoprotein M6A | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q34.2 | ||
| Entrez ID: 2823 | HGNC ID: HGNC:4460 | Ensembl Gene: ENSG00000150625 | OMIM ID: 601275 |
| Drug and gene relationship at DGIdb | |||
Expression of GPM6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPM6A | 2823 | 209470_s_at | -1.0757 | 0.7362 | |
| GSE20347 | GPM6A | 2823 | 209470_s_at | -0.7028 | 0.1292 | |
| GSE23400 | GPM6A | 2823 | 209470_s_at | -0.3917 | 0.0749 | |
| GSE26886 | GPM6A | 2823 | 236024_at | 0.0447 | 0.7428 | |
| GSE29001 | GPM6A | 2823 | 209469_at | -0.8805 | 0.3493 | |
| GSE38129 | GPM6A | 2823 | 209469_at | -1.0736 | 0.1181 | |
| GSE45670 | GPM6A | 2823 | 236024_at | -0.1488 | 0.4296 | |
| GSE53622 | GPM6A | 2823 | 29178 | -0.3797 | 0.1078 | |
| GSE53624 | GPM6A | 2823 | 29178 | -0.0524 | 0.7422 | |
| GSE63941 | GPM6A | 2823 | 236024_at | 0.1559 | 0.3283 | |
| GSE77861 | GPM6A | 2823 | 236024_at | 0.0016 | 0.9853 | |
| GSE97050 | GPM6A | 2823 | A_23_P121545 | -0.6689 | 0.3399 | |
| SRP007169 | GPM6A | 2823 | RNAseq | -0.6841 | 0.3206 | |
| SRP064894 | GPM6A | 2823 | RNAseq | 2.4438 | 0.0000 | |
| SRP133303 | GPM6A | 2823 | RNAseq | -0.0782 | 0.6131 | |
| SRP193095 | GPM6A | 2823 | RNAseq | -0.0199 | 0.9364 | |
| TCGA | GPM6A | 2823 | RNAseq | -0.7897 | 0.1810 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GPM6A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPM6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPM6A | 2823 | 1 | 11 | 18 | |
| GSE20123 | GPM6A | 2823 | 1 | 11 | 18 | |
| GSE43470 | GPM6A | 2823 | 0 | 14 | 29 | |
| GSE46452 | GPM6A | 2823 | 1 | 36 | 22 | |
| GSE47630 | GPM6A | 2823 | 0 | 22 | 18 | |
| GSE54993 | GPM6A | 2823 | 10 | 0 | 60 | |
| GSE54994 | GPM6A | 2823 | 2 | 12 | 39 | |
| GSE60625 | GPM6A | 2823 | 0 | 0 | 11 | |
| GSE74703 | GPM6A | 2823 | 0 | 12 | 24 | |
| GSE74704 | GPM6A | 2823 | 0 | 5 | 15 | |
| TCGA | GPM6A | 2823 | 10 | 36 | 50 |
Total number of gains: 25; Total number of losses: 159; Total Number of normals: 304.
Somatic mutations of GPM6A:
Generating mutation plots.
Highly correlated genes for GPM6A:
Showing top 20/429 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPM6A | SMPX | 0.843172 | 9 | 0 | 9 |
| GPM6A | NECAB1 | 0.836024 | 3 | 0 | 3 |
| GPM6A | GADL1 | 0.790932 | 5 | 0 | 5 |
| GPM6A | ADARB1 | 0.767013 | 5 | 0 | 5 |
| GPM6A | CNN1 | 0.766128 | 5 | 0 | 5 |
| GPM6A | TLN1 | 0.756061 | 4 | 0 | 4 |
| GPM6A | VIP | 0.75202 | 7 | 0 | 7 |
| GPM6A | ITGB1BP2 | 0.749678 | 6 | 0 | 5 |
| GPM6A | STARD13 | 0.748073 | 5 | 0 | 5 |
| GPM6A | RASL12 | 0.743746 | 7 | 0 | 6 |
| GPM6A | POPDC2 | 0.742723 | 7 | 0 | 7 |
| GPM6A | PLN | 0.737502 | 7 | 0 | 7 |
| GPM6A | BRINP3 | 0.734698 | 6 | 0 | 4 |
| GPM6A | NRK | 0.731403 | 4 | 0 | 4 |
| GPM6A | HSPB7 | 0.722803 | 8 | 0 | 7 |
| GPM6A | ADAMTSL3 | 0.720605 | 9 | 0 | 9 |
| GPM6A | ISCU | 0.720092 | 5 | 0 | 5 |
| GPM6A | MYOM1 | 0.715834 | 9 | 0 | 8 |
| GPM6A | KANK2 | 0.715285 | 6 | 0 | 5 |
| GPM6A | FLNA | 0.714813 | 4 | 0 | 4 |
For details and further investigation, click here
