| Full name: peptidylprolyl isomerase C | Alias Symbol: CYPC | ||
| Type: protein-coding gene | Cytoband: 5q23.2 | ||
| Entrez ID: 5480 | HGNC ID: HGNC:9256 | Ensembl Gene: ENSG00000168938 | OMIM ID: 123842 |
| Drug and gene relationship at DGIdb | |||
Expression of PPIC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPIC | 5480 | 204517_at | -0.6779 | 0.3147 | |
| GSE20347 | PPIC | 5480 | 204517_at | -1.2143 | 0.0000 | |
| GSE23400 | PPIC | 5480 | 204517_at | -0.4321 | 0.0000 | |
| GSE26886 | PPIC | 5480 | 204517_at | -1.9496 | 0.0000 | |
| GSE29001 | PPIC | 5480 | 204517_at | -0.5777 | 0.0087 | |
| GSE38129 | PPIC | 5480 | 204517_at | -0.7306 | 0.0002 | |
| GSE45670 | PPIC | 5480 | 204517_at | -0.1618 | 0.5421 | |
| GSE53622 | PPIC | 5480 | 95309 | -0.5112 | 0.0000 | |
| GSE53624 | PPIC | 5480 | 95309 | -0.5953 | 0.0000 | |
| GSE63941 | PPIC | 5480 | 204517_at | -1.2868 | 0.3305 | |
| GSE77861 | PPIC | 5480 | 204517_at | -1.3110 | 0.0137 | |
| GSE97050 | PPIC | 5480 | A_23_P422724 | 0.0106 | 0.9711 | |
| SRP007169 | PPIC | 5480 | RNAseq | -1.6122 | 0.0000 | |
| SRP008496 | PPIC | 5480 | RNAseq | -1.4600 | 0.0000 | |
| SRP064894 | PPIC | 5480 | RNAseq | 0.2891 | 0.1330 | |
| SRP133303 | PPIC | 5480 | RNAseq | -0.2336 | 0.1780 | |
| SRP159526 | PPIC | 5480 | RNAseq | -0.6187 | 0.2217 | |
| SRP193095 | PPIC | 5480 | RNAseq | -1.3123 | 0.0000 | |
| SRP219564 | PPIC | 5480 | RNAseq | -0.3296 | 0.3177 | |
| TCGA | PPIC | 5480 | RNAseq | 0.0544 | 0.4537 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by PPIC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPIC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPIC | 5480 | 1 | 13 | 16 | |
| GSE20123 | PPIC | 5480 | 1 | 13 | 16 | |
| GSE43470 | PPIC | 5480 | 3 | 8 | 32 | |
| GSE46452 | PPIC | 5480 | 0 | 27 | 32 | |
| GSE47630 | PPIC | 5480 | 0 | 21 | 19 | |
| GSE54993 | PPIC | 5480 | 9 | 1 | 60 | |
| GSE54994 | PPIC | 5480 | 2 | 14 | 37 | |
| GSE60625 | PPIC | 5480 | 0 | 0 | 11 | |
| GSE74703 | PPIC | 5480 | 2 | 6 | 28 | |
| GSE74704 | PPIC | 5480 | 1 | 7 | 12 | |
| TCGA | PPIC | 5480 | 2 | 41 | 53 |
Total number of gains: 21; Total number of losses: 151; Total Number of normals: 316.
Somatic mutations of PPIC:
Generating mutation plots.
Highly correlated genes for PPIC:
Showing top 20/1533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPIC | TAX1BP3 | 0.770328 | 3 | 0 | 3 |
| PPIC | CCNYL1 | 0.766832 | 5 | 0 | 5 |
| PPIC | SH3PXD2A-AS1 | 0.741635 | 3 | 0 | 3 |
| PPIC | GJB2 | 0.741601 | 4 | 0 | 4 |
| PPIC | AMOTL1 | 0.740718 | 3 | 0 | 3 |
| PPIC | SPAG17 | 0.740664 | 4 | 0 | 4 |
| PPIC | TMEM219 | 0.736391 | 3 | 0 | 3 |
| PPIC | SBSN | 0.733183 | 5 | 0 | 5 |
| PPIC | VPS4B | 0.730606 | 11 | 0 | 11 |
| PPIC | SLC25A51 | 0.727823 | 4 | 0 | 4 |
| PPIC | FCHO2 | 0.727771 | 8 | 0 | 8 |
| PPIC | ACAA1 | 0.727607 | 9 | 0 | 8 |
| PPIC | FAM174A | 0.726184 | 8 | 0 | 7 |
| PPIC | VSIG10L | 0.721852 | 6 | 0 | 5 |
| PPIC | METRNL | 0.7218 | 6 | 0 | 6 |
| PPIC | ZNF185 | 0.721545 | 10 | 0 | 10 |
| PPIC | GPR108 | 0.719071 | 3 | 0 | 3 |
| PPIC | KCNK13 | 0.717814 | 3 | 0 | 3 |
| PPIC | ZCCHC9 | 0.715673 | 5 | 0 | 4 |
| PPIC | CYSRT1 | 0.715456 | 6 | 0 | 5 |
For details and further investigation, click here
