| Full name: Tax1 binding protein 3 | Alias Symbol: TIP-1 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 30851 | HGNC ID: HGNC:30684 | Ensembl Gene: ENSG00000213977 | OMIM ID: 616484 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TAX1BP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TAX1BP3 | 30851 | 63122 | -0.4124 | 0.0005 | |
| GSE53624 | TAX1BP3 | 30851 | 63122 | -0.5089 | 0.0000 | |
| GSE97050 | TAX1BP3 | 30851 | A_23_P38468 | 0.1361 | 0.7208 | |
| SRP007169 | TAX1BP3 | 30851 | RNAseq | -1.4735 | 0.0072 | |
| SRP008496 | TAX1BP3 | 30851 | RNAseq | -1.4512 | 0.0000 | |
| SRP064894 | TAX1BP3 | 30851 | RNAseq | -0.1114 | 0.6147 | |
| SRP133303 | TAX1BP3 | 30851 | RNAseq | -0.4370 | 0.0330 | |
| SRP159526 | TAX1BP3 | 30851 | RNAseq | -0.6687 | 0.0528 | |
| SRP193095 | TAX1BP3 | 30851 | RNAseq | -0.5551 | 0.0001 | |
| SRP219564 | TAX1BP3 | 30851 | RNAseq | -0.2040 | 0.4995 | |
| TCGA | TAX1BP3 | 30851 | RNAseq | 0.0305 | 0.5988 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TAX1BP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAX1BP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAX1BP3 | 30851 | 5 | 3 | 22 | |
| GSE20123 | TAX1BP3 | 30851 | 5 | 4 | 21 | |
| GSE43470 | TAX1BP3 | 30851 | 1 | 6 | 36 | |
| GSE46452 | TAX1BP3 | 30851 | 34 | 1 | 24 | |
| GSE47630 | TAX1BP3 | 30851 | 7 | 1 | 32 | |
| GSE54993 | TAX1BP3 | 30851 | 4 | 3 | 63 | |
| GSE54994 | TAX1BP3 | 30851 | 5 | 9 | 39 | |
| GSE60625 | TAX1BP3 | 30851 | 4 | 0 | 7 | |
| GSE74703 | TAX1BP3 | 30851 | 1 | 3 | 32 | |
| GSE74704 | TAX1BP3 | 30851 | 3 | 2 | 15 | |
| TCGA | TAX1BP3 | 30851 | 17 | 21 | 58 |
Total number of gains: 86; Total number of losses: 53; Total Number of normals: 349.
Somatic mutations of TAX1BP3:
Generating mutation plots.
Highly correlated genes for TAX1BP3:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAX1BP3 | PAQR7 | 0.790623 | 3 | 0 | 3 |
| TAX1BP3 | PPIC | 0.770328 | 3 | 0 | 3 |
| TAX1BP3 | ZDHHC5 | 0.755213 | 3 | 0 | 3 |
| TAX1BP3 | RAC1 | 0.740845 | 3 | 0 | 3 |
| TAX1BP3 | COMTD1 | 0.740253 | 3 | 0 | 3 |
| TAX1BP3 | MFSD5 | 0.739255 | 3 | 0 | 3 |
| TAX1BP3 | STXBP5 | 0.730044 | 3 | 0 | 3 |
| TAX1BP3 | NLRX1 | 0.728275 | 3 | 0 | 3 |
| TAX1BP3 | MTPN | 0.716798 | 3 | 0 | 3 |
| TAX1BP3 | TMEM19 | 0.716557 | 3 | 0 | 3 |
| TAX1BP3 | ARPC2 | 0.715602 | 3 | 0 | 3 |
| TAX1BP3 | GALE | 0.714478 | 3 | 0 | 3 |
| TAX1BP3 | OSTF1 | 0.713196 | 3 | 0 | 3 |
| TAX1BP3 | LIMK2 | 0.711872 | 3 | 0 | 3 |
| TAX1BP3 | MAP2K4 | 0.711437 | 3 | 0 | 3 |
| TAX1BP3 | RER1 | 0.709535 | 3 | 0 | 3 |
| TAX1BP3 | TNIP1 | 0.709116 | 3 | 0 | 3 |
| TAX1BP3 | CASP4 | 0.708789 | 3 | 0 | 3 |
| TAX1BP3 | CIB1 | 0.708696 | 3 | 0 | 3 |
| TAX1BP3 | PI4K2A | 0.706352 | 3 | 0 | 3 |
For details and further investigation, click here
