| Full name: protein phosphatase 2 regulatory subunit B'delta | Alias Symbol: B56D|B56delta | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 5528 | HGNC ID: HGNC:9312 | Ensembl Gene: ENSG00000112640 | OMIM ID: 601646 |
| Drug and gene relationship at DGIdb | |||
PPP2R5D involved pathways:
Expression of PPP2R5D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R5D | 5528 | 202513_s_at | 0.3952 | 0.1425 | |
| GSE20347 | PPP2R5D | 5528 | 202513_s_at | 0.1238 | 0.1577 | |
| GSE23400 | PPP2R5D | 5528 | 202513_s_at | 0.0346 | 0.3557 | |
| GSE26886 | PPP2R5D | 5528 | 202513_s_at | 0.2266 | 0.0372 | |
| GSE29001 | PPP2R5D | 5528 | 202513_s_at | 0.0354 | 0.8945 | |
| GSE38129 | PPP2R5D | 5528 | 202513_s_at | -0.0258 | 0.7509 | |
| GSE45670 | PPP2R5D | 5528 | 202513_s_at | 0.1252 | 0.0827 | |
| GSE53622 | PPP2R5D | 5528 | 21027 | -0.0734 | 0.1137 | |
| GSE53624 | PPP2R5D | 5528 | 21027 | 0.3872 | 0.0000 | |
| GSE63941 | PPP2R5D | 5528 | 202513_s_at | 0.1786 | 0.5726 | |
| GSE77861 | PPP2R5D | 5528 | 202513_s_at | -0.0443 | 0.8349 | |
| GSE97050 | PPP2R5D | 5528 | A_24_P294931 | -0.0683 | 0.8353 | |
| SRP007169 | PPP2R5D | 5528 | RNAseq | 0.1880 | 0.5943 | |
| SRP008496 | PPP2R5D | 5528 | RNAseq | 0.1958 | 0.3193 | |
| SRP064894 | PPP2R5D | 5528 | RNAseq | 0.3199 | 0.1518 | |
| SRP133303 | PPP2R5D | 5528 | RNAseq | 0.3497 | 0.0257 | |
| SRP159526 | PPP2R5D | 5528 | RNAseq | 0.2902 | 0.1078 | |
| SRP193095 | PPP2R5D | 5528 | RNAseq | 0.3426 | 0.0026 | |
| SRP219564 | PPP2R5D | 5528 | RNAseq | 0.1537 | 0.5942 | |
| TCGA | PPP2R5D | 5528 | RNAseq | 0.1057 | 0.0341 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP2R5D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R5D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R5D | 5528 | 7 | 0 | 23 | |
| GSE20123 | PPP2R5D | 5528 | 7 | 0 | 23 | |
| GSE43470 | PPP2R5D | 5528 | 6 | 0 | 37 | |
| GSE46452 | PPP2R5D | 5528 | 2 | 9 | 48 | |
| GSE47630 | PPP2R5D | 5528 | 8 | 4 | 28 | |
| GSE54993 | PPP2R5D | 5528 | 3 | 2 | 65 | |
| GSE54994 | PPP2R5D | 5528 | 11 | 4 | 38 | |
| GSE60625 | PPP2R5D | 5528 | 0 | 1 | 10 | |
| GSE74703 | PPP2R5D | 5528 | 6 | 0 | 30 | |
| GSE74704 | PPP2R5D | 5528 | 3 | 0 | 17 | |
| TCGA | PPP2R5D | 5528 | 21 | 13 | 62 |
Total number of gains: 74; Total number of losses: 33; Total Number of normals: 381.
Somatic mutations of PPP2R5D:
Generating mutation plots.
Highly correlated genes for PPP2R5D:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R5D | TMUB1 | 0.759562 | 3 | 0 | 3 |
| PPP2R5D | DNAL4 | 0.74523 | 3 | 0 | 3 |
| PPP2R5D | PHGR1 | 0.739025 | 3 | 0 | 3 |
| PPP2R5D | OR7A17 | 0.729264 | 3 | 0 | 3 |
| PPP2R5D | ZNF157 | 0.725859 | 4 | 0 | 3 |
| PPP2R5D | LIPE | 0.721278 | 3 | 0 | 3 |
| PPP2R5D | TRIM31 | 0.718497 | 4 | 0 | 3 |
| PPP2R5D | RAD51D | 0.713494 | 4 | 0 | 3 |
| PPP2R5D | C20orf144 | 0.711651 | 3 | 0 | 3 |
| PPP2R5D | TRPM3 | 0.711588 | 4 | 0 | 3 |
| PPP2R5D | REG3A | 0.703018 | 3 | 0 | 3 |
| PPP2R5D | FBRSL1 | 0.700605 | 3 | 0 | 3 |
| PPP2R5D | CACTIN | 0.691283 | 3 | 0 | 3 |
| PPP2R5D | MIIP | 0.688837 | 4 | 0 | 3 |
| PPP2R5D | ZNF511 | 0.687536 | 3 | 0 | 3 |
| PPP2R5D | S1PR4 | 0.685788 | 3 | 0 | 3 |
| PPP2R5D | OR2H2 | 0.685636 | 3 | 0 | 3 |
| PPP2R5D | MAPK15 | 0.683943 | 3 | 0 | 3 |
| PPP2R5D | DRD2 | 0.671352 | 3 | 0 | 3 |
| PPP2R5D | NFKBIB | 0.667335 | 3 | 0 | 3 |
For details and further investigation, click here
