| Full name: DNA primase subunit 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p11.2 | ||
| Entrez ID: 5558 | HGNC ID: HGNC:9370 | Ensembl Gene: ENSG00000146143 | OMIM ID: 176636 |
| Drug and gene relationship at DGIdb | |||
Expression of PRIM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRIM2 | 5558 | 205628_at | 0.8441 | 0.0378 | |
| GSE20347 | PRIM2 | 5558 | 205628_at | 0.9148 | 0.0000 | |
| GSE23400 | PRIM2 | 5558 | 215708_s_at | 0.4261 | 0.0000 | |
| GSE26886 | PRIM2 | 5558 | 205628_at | 1.3613 | 0.0000 | |
| GSE29001 | PRIM2 | 5558 | 205628_at | 0.7140 | 0.0034 | |
| GSE38129 | PRIM2 | 5558 | 205628_at | 1.1157 | 0.0000 | |
| GSE45670 | PRIM2 | 5558 | 205628_at | 0.9832 | 0.0006 | |
| GSE53622 | PRIM2 | 5558 | 120985 | 1.0069 | 0.0000 | |
| GSE53624 | PRIM2 | 5558 | 120985 | 1.4164 | 0.0000 | |
| GSE63941 | PRIM2 | 5558 | 215708_s_at | 1.4383 | 0.0274 | |
| GSE77861 | PRIM2 | 5558 | 215709_at | -0.0259 | 0.8093 | |
| GSE97050 | PRIM2 | 5558 | A_33_P3261982 | 0.2185 | 0.6476 | |
| SRP007169 | PRIM2 | 5558 | RNAseq | 1.6557 | 0.0002 | |
| SRP008496 | PRIM2 | 5558 | RNAseq | 1.1145 | 0.0004 | |
| SRP064894 | PRIM2 | 5558 | RNAseq | 1.3018 | 0.0000 | |
| SRP133303 | PRIM2 | 5558 | RNAseq | 1.1579 | 0.0000 | |
| SRP159526 | PRIM2 | 5558 | RNAseq | 1.3101 | 0.0007 | |
| SRP193095 | PRIM2 | 5558 | RNAseq | 0.8013 | 0.0000 | |
| SRP219564 | PRIM2 | 5558 | RNAseq | 1.1462 | 0.0007 | |
| TCGA | PRIM2 | 5558 | RNAseq | 0.6145 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by PRIM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRIM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRIM2 | 5558 | 7 | 2 | 21 | |
| GSE20123 | PRIM2 | 5558 | 7 | 2 | 21 | |
| GSE43470 | PRIM2 | 5558 | 4 | 0 | 39 | |
| GSE46452 | PRIM2 | 5558 | 2 | 10 | 47 | |
| GSE47630 | PRIM2 | 5558 | 7 | 5 | 28 | |
| GSE54993 | PRIM2 | 5558 | 3 | 2 | 65 | |
| GSE54994 | PRIM2 | 5558 | 9 | 4 | 40 | |
| GSE60625 | PRIM2 | 5558 | 0 | 1 | 10 | |
| GSE74703 | PRIM2 | 5558 | 4 | 0 | 32 | |
| GSE74704 | PRIM2 | 5558 | 3 | 1 | 16 | |
| TCGA | PRIM2 | 5558 | 22 | 11 | 63 |
Total number of gains: 68; Total number of losses: 38; Total Number of normals: 382.
Somatic mutations of PRIM2:
Generating mutation plots.
Highly correlated genes for PRIM2:
Showing top 20/1039 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRIM2 | SLC7A6OS | 0.805362 | 3 | 0 | 3 |
| PRIM2 | MMS22L | 0.794202 | 3 | 0 | 3 |
| PRIM2 | TPX2 | 0.785793 | 11 | 0 | 11 |
| PRIM2 | PGM2L1 | 0.785303 | 4 | 0 | 4 |
| PRIM2 | HJURP | 0.76285 | 11 | 0 | 11 |
| PRIM2 | KIF14 | 0.761421 | 11 | 0 | 11 |
| PRIM2 | SPC25 | 0.759108 | 10 | 0 | 10 |
| PRIM2 | NRM | 0.757434 | 7 | 0 | 7 |
| PRIM2 | CENPE | 0.755729 | 11 | 0 | 10 |
| PRIM2 | NEK2 | 0.751189 | 11 | 0 | 11 |
| PRIM2 | PET117 | 0.750548 | 3 | 0 | 3 |
| PRIM2 | MCM10 | 0.747111 | 11 | 0 | 11 |
| PRIM2 | SNRPC | 0.744068 | 11 | 0 | 11 |
| PRIM2 | FANCI | 0.743538 | 11 | 0 | 11 |
| PRIM2 | PRKDC | 0.741299 | 10 | 0 | 10 |
| PRIM2 | EME1 | 0.740543 | 5 | 0 | 5 |
| PRIM2 | MYBL2 | 0.739773 | 11 | 0 | 11 |
| PRIM2 | MTERF3 | 0.739648 | 7 | 0 | 7 |
| PRIM2 | NTMT1 | 0.738678 | 5 | 0 | 5 |
| PRIM2 | SIX4 | 0.735832 | 6 | 0 | 6 |
For details and further investigation, click here
