| Full name: MYB proto-oncogene like 2 | Alias Symbol: BMYB|B-MYB | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 4605 | HGNC ID: HGNC:7548 | Ensembl Gene: ENSG00000101057 | OMIM ID: 601415 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MYBL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYBL2 | 4605 | 201710_at | 1.8306 | 0.0051 | |
| GSE20347 | MYBL2 | 4605 | 201710_at | 1.3186 | 0.0000 | |
| GSE23400 | MYBL2 | 4605 | 201710_at | 0.6454 | 0.0000 | |
| GSE26886 | MYBL2 | 4605 | 201710_at | 1.0669 | 0.0000 | |
| GSE29001 | MYBL2 | 4605 | 201710_at | 1.0281 | 0.0001 | |
| GSE38129 | MYBL2 | 4605 | 201710_at | 1.2868 | 0.0000 | |
| GSE45670 | MYBL2 | 4605 | 201710_at | 0.9619 | 0.0000 | |
| GSE53622 | MYBL2 | 4605 | 44698 | 2.0461 | 0.0000 | |
| GSE53624 | MYBL2 | 4605 | 44698 | 1.9128 | 0.0000 | |
| GSE63941 | MYBL2 | 4605 | 201710_at | 2.1800 | 0.0013 | |
| GSE77861 | MYBL2 | 4605 | 201710_at | 0.5782 | 0.0043 | |
| GSE97050 | MYBL2 | 4605 | A_23_P143190 | 1.4802 | 0.1413 | |
| SRP007169 | MYBL2 | 4605 | RNAseq | 3.2794 | 0.0000 | |
| SRP008496 | MYBL2 | 4605 | RNAseq | 3.0201 | 0.0000 | |
| SRP064894 | MYBL2 | 4605 | RNAseq | 2.5905 | 0.0000 | |
| SRP133303 | MYBL2 | 4605 | RNAseq | 2.4472 | 0.0000 | |
| SRP159526 | MYBL2 | 4605 | RNAseq | 2.3033 | 0.0000 | |
| SRP193095 | MYBL2 | 4605 | RNAseq | 1.7927 | 0.0000 | |
| SRP219564 | MYBL2 | 4605 | RNAseq | 3.4753 | 0.0000 | |
| TCGA | MYBL2 | 4605 | RNAseq | 1.2235 | 0.0000 |
Upregulated datasets: 16; Downregulated datasets: 0.
Survival by MYBL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYBL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYBL2 | 4605 | 13 | 2 | 15 | |
| GSE20123 | MYBL2 | 4605 | 13 | 2 | 15 | |
| GSE43470 | MYBL2 | 4605 | 12 | 1 | 30 | |
| GSE46452 | MYBL2 | 4605 | 29 | 0 | 30 | |
| GSE47630 | MYBL2 | 4605 | 24 | 0 | 16 | |
| GSE54993 | MYBL2 | 4605 | 0 | 17 | 53 | |
| GSE54994 | MYBL2 | 4605 | 25 | 0 | 28 | |
| GSE60625 | MYBL2 | 4605 | 0 | 0 | 11 | |
| GSE74703 | MYBL2 | 4605 | 10 | 1 | 25 | |
| GSE74704 | MYBL2 | 4605 | 9 | 0 | 11 | |
| TCGA | MYBL2 | 4605 | 47 | 2 | 47 |
Total number of gains: 182; Total number of losses: 25; Total Number of normals: 281.
Somatic mutations of MYBL2:
Generating mutation plots.
Highly correlated genes for MYBL2:
Showing top 20/2190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYBL2 | UBE2C | 0.878238 | 12 | 0 | 12 |
| MYBL2 | TPX2 | 0.861431 | 12 | 0 | 12 |
| MYBL2 | AURKB | 0.840864 | 12 | 0 | 12 |
| MYBL2 | UBE2T | 0.839542 | 8 | 0 | 8 |
| MYBL2 | CDCA5 | 0.837969 | 7 | 0 | 7 |
| MYBL2 | CKS1B | 0.836757 | 12 | 0 | 12 |
| MYBL2 | MCM2 | 0.832303 | 12 | 0 | 12 |
| MYBL2 | CENPW | 0.831776 | 7 | 0 | 7 |
| MYBL2 | UHRF1 | 0.829813 | 8 | 0 | 8 |
| MYBL2 | SLC19A1 | 0.827919 | 3 | 0 | 3 |
| MYBL2 | RFC4 | 0.827897 | 12 | 0 | 12 |
| MYBL2 | TRIP13 | 0.826345 | 12 | 0 | 12 |
| MYBL2 | CDKN3 | 0.824342 | 12 | 0 | 12 |
| MYBL2 | DNMT1 | 0.823365 | 12 | 0 | 12 |
| MYBL2 | TMC8 | 0.819709 | 3 | 0 | 3 |
| MYBL2 | CDC45 | 0.819637 | 12 | 0 | 12 |
| MYBL2 | RNASEH2A | 0.818738 | 12 | 0 | 12 |
| MYBL2 | AURKA | 0.818629 | 12 | 0 | 12 |
| MYBL2 | FOXM1 | 0.817588 | 12 | 0 | 12 |
| MYBL2 | GINS2 | 0.817058 | 11 | 0 | 11 |
For details and further investigation, click here
