| Full name: Holliday junction recognition protein | Alias Symbol: DKFZp762E1312|URLC9|hFLEG1|FAKTS | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 55355 | HGNC ID: HGNC:25444 | Ensembl Gene: ENSG00000123485 | OMIM ID: 612667 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HJURP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HJURP | 55355 | 218726_at | 0.9228 | 0.0493 | |
| GSE20347 | HJURP | 55355 | 218726_at | 1.4837 | 0.0000 | |
| GSE23400 | HJURP | 55355 | 218726_at | 0.9088 | 0.0000 | |
| GSE26886 | HJURP | 55355 | 218726_at | 0.4165 | 0.1108 | |
| GSE29001 | HJURP | 55355 | 218726_at | 0.8790 | 0.0003 | |
| GSE38129 | HJURP | 55355 | 218726_at | 1.6023 | 0.0000 | |
| GSE45670 | HJURP | 55355 | 218726_at | 1.5920 | 0.0000 | |
| GSE53622 | HJURP | 55355 | 65765 | 1.6935 | 0.0000 | |
| GSE53624 | HJURP | 55355 | 65765 | 2.1810 | 0.0000 | |
| GSE63941 | HJURP | 55355 | 218726_at | 2.5898 | 0.0011 | |
| GSE77861 | HJURP | 55355 | 218726_at | 1.0377 | 0.0028 | |
| GSE97050 | HJURP | 55355 | A_33_P3807062 | 1.3414 | 0.0903 | |
| SRP007169 | HJURP | 55355 | RNAseq | 3.0528 | 0.0000 | |
| SRP008496 | HJURP | 55355 | RNAseq | 2.3366 | 0.0000 | |
| SRP064894 | HJURP | 55355 | RNAseq | 1.9522 | 0.0000 | |
| SRP133303 | HJURP | 55355 | RNAseq | 1.5905 | 0.0000 | |
| SRP159526 | HJURP | 55355 | RNAseq | 2.0281 | 0.0000 | |
| SRP193095 | HJURP | 55355 | RNAseq | 1.1248 | 0.0000 | |
| SRP219564 | HJURP | 55355 | RNAseq | 1.3849 | 0.0246 | |
| TCGA | HJURP | 55355 | RNAseq | 1.3376 | 0.0000 |
Upregulated datasets: 15; Downregulated datasets: 0.
Survival by HJURP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HJURP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HJURP | 55355 | 1 | 11 | 18 | |
| GSE20123 | HJURP | 55355 | 1 | 11 | 18 | |
| GSE43470 | HJURP | 55355 | 1 | 9 | 33 | |
| GSE46452 | HJURP | 55355 | 0 | 5 | 54 | |
| GSE47630 | HJURP | 55355 | 4 | 5 | 31 | |
| GSE54993 | HJURP | 55355 | 3 | 2 | 65 | |
| GSE54994 | HJURP | 55355 | 6 | 10 | 37 | |
| GSE60625 | HJURP | 55355 | 0 | 3 | 8 | |
| GSE74703 | HJURP | 55355 | 1 | 7 | 28 | |
| GSE74704 | HJURP | 55355 | 1 | 5 | 14 | |
| TCGA | HJURP | 55355 | 12 | 28 | 56 |
Total number of gains: 30; Total number of losses: 96; Total Number of normals: 362.
Somatic mutations of HJURP:
Generating mutation plots.
Highly correlated genes for HJURP:
Showing top 20/2119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HJURP | CDCA2 | 0.907859 | 6 | 0 | 6 |
| HJURP | BUB1B | 0.847159 | 9 | 0 | 9 |
| HJURP | DLGAP5 | 0.840168 | 11 | 0 | 11 |
| HJURP | UBE2C | 0.834158 | 13 | 0 | 13 |
| HJURP | NCAPH | 0.831039 | 9 | 0 | 9 |
| HJURP | CENPF | 0.826289 | 13 | 0 | 13 |
| HJURP | ATAD2 | 0.826212 | 12 | 0 | 12 |
| HJURP | NEK2 | 0.82273 | 13 | 0 | 13 |
| HJURP | GINS1 | 0.818656 | 12 | 0 | 12 |
| HJURP | ANLN | 0.818158 | 8 | 0 | 8 |
| HJURP | BUB1 | 0.817238 | 11 | 0 | 10 |
| HJURP | KIF14 | 0.816488 | 13 | 0 | 12 |
| HJURP | NCAPG2 | 0.815397 | 11 | 0 | 11 |
| HJURP | NUF2 | 0.813844 | 9 | 0 | 8 |
| HJURP | TOP2A | 0.813706 | 13 | 0 | 12 |
| HJURP | KIF20A | 0.813493 | 13 | 0 | 12 |
| HJURP | ASPM | 0.813027 | 13 | 0 | 12 |
| HJURP | CEP55 | 0.812673 | 13 | 0 | 12 |
| HJURP | TPX2 | 0.810081 | 13 | 0 | 12 |
| HJURP | WDHD1 | 0.808096 | 12 | 0 | 12 |
For details and further investigation, click here
