| Full name: phosphoribosyl pyrophosphate synthetase associated protein 1 | Alias Symbol: PAP39 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 5635 | HGNC ID: HGNC:9466 | Ensembl Gene: ENSG00000161542 | OMIM ID: 601249 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPSAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPSAP1 | 5635 | 202529_at | -0.6533 | 0.1963 | |
| GSE20347 | PRPSAP1 | 5635 | 202529_at | -0.5122 | 0.0014 | |
| GSE23400 | PRPSAP1 | 5635 | 202529_at | -0.2796 | 0.0028 | |
| GSE26886 | PRPSAP1 | 5635 | 202529_at | -1.3403 | 0.0000 | |
| GSE29001 | PRPSAP1 | 5635 | 202529_at | -0.5036 | 0.0642 | |
| GSE38129 | PRPSAP1 | 5635 | 202529_at | -0.2413 | 0.1030 | |
| GSE45670 | PRPSAP1 | 5635 | 202529_at | -0.3219 | 0.0657 | |
| GSE53622 | PRPSAP1 | 5635 | 77675 | -0.5308 | 0.0000 | |
| GSE53624 | PRPSAP1 | 5635 | 77675 | -0.6905 | 0.0000 | |
| GSE63941 | PRPSAP1 | 5635 | 202529_at | 0.1987 | 0.5627 | |
| GSE77861 | PRPSAP1 | 5635 | 202529_at | -0.1339 | 0.4825 | |
| GSE97050 | PRPSAP1 | 5635 | A_23_P15305 | -0.1693 | 0.5367 | |
| SRP007169 | PRPSAP1 | 5635 | RNAseq | -0.7081 | 0.1203 | |
| SRP008496 | PRPSAP1 | 5635 | RNAseq | -0.9998 | 0.0003 | |
| SRP064894 | PRPSAP1 | 5635 | RNAseq | -0.7131 | 0.0000 | |
| SRP133303 | PRPSAP1 | 5635 | RNAseq | -0.1352 | 0.5486 | |
| SRP159526 | PRPSAP1 | 5635 | RNAseq | 0.1164 | 0.7338 | |
| SRP193095 | PRPSAP1 | 5635 | RNAseq | -0.5977 | 0.0000 | |
| SRP219564 | PRPSAP1 | 5635 | RNAseq | -0.9356 | 0.0038 | |
| TCGA | PRPSAP1 | 5635 | RNAseq | 0.0244 | 0.6394 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PRPSAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPSAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPSAP1 | 5635 | 7 | 2 | 21 | |
| GSE20123 | PRPSAP1 | 5635 | 7 | 2 | 21 | |
| GSE43470 | PRPSAP1 | 5635 | 5 | 3 | 35 | |
| GSE46452 | PRPSAP1 | 5635 | 34 | 0 | 25 | |
| GSE47630 | PRPSAP1 | 5635 | 8 | 1 | 31 | |
| GSE54993 | PRPSAP1 | 5635 | 2 | 5 | 63 | |
| GSE54994 | PRPSAP1 | 5635 | 10 | 4 | 39 | |
| GSE60625 | PRPSAP1 | 5635 | 6 | 0 | 5 | |
| GSE74703 | PRPSAP1 | 5635 | 5 | 1 | 30 | |
| GSE74704 | PRPSAP1 | 5635 | 5 | 1 | 14 | |
| TCGA | PRPSAP1 | 5635 | 31 | 10 | 55 |
Total number of gains: 120; Total number of losses: 29; Total Number of normals: 339.
Somatic mutations of PRPSAP1:
Generating mutation plots.
Highly correlated genes for PRPSAP1:
Showing top 20/1241 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPSAP1 | ZFC3H1 | 0.829257 | 3 | 0 | 3 |
| PRPSAP1 | IMPACT | 0.774863 | 3 | 0 | 3 |
| PRPSAP1 | CCNYL1 | 0.739968 | 4 | 0 | 3 |
| PRPSAP1 | ZNF770 | 0.734684 | 4 | 0 | 4 |
| PRPSAP1 | SLC46A2 | 0.729811 | 6 | 0 | 6 |
| PRPSAP1 | C15orf62 | 0.728468 | 6 | 0 | 4 |
| PRPSAP1 | SREBF2 | 0.724109 | 3 | 0 | 3 |
| PRPSAP1 | MKKS | 0.719806 | 3 | 0 | 3 |
| PRPSAP1 | MCU | 0.719305 | 3 | 0 | 3 |
| PRPSAP1 | USP54 | 0.717798 | 6 | 0 | 6 |
| PRPSAP1 | AP3M1 | 0.717642 | 3 | 0 | 3 |
| PRPSAP1 | PRPF38A | 0.715737 | 3 | 0 | 3 |
| PRPSAP1 | SLC10A5 | 0.713862 | 3 | 0 | 3 |
| PRPSAP1 | LRIG3 | 0.712973 | 3 | 0 | 3 |
| PRPSAP1 | LIPH | 0.708652 | 5 | 0 | 5 |
| PRPSAP1 | TAB3 | 0.704286 | 6 | 0 | 5 |
| PRPSAP1 | FUT11 | 0.70399 | 3 | 0 | 3 |
| PRPSAP1 | CTTNBP2NL | 0.702982 | 6 | 0 | 5 |
| PRPSAP1 | SAMD5 | 0.702046 | 7 | 0 | 7 |
| PRPSAP1 | RHBDL2 | 0.701384 | 4 | 0 | 4 |
For details and further investigation, click here
