| Full name: rhomboid like 2 | Alias Symbol: FLJ20435 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 54933 | HGNC ID: HGNC:16083 | Ensembl Gene: ENSG00000158315 | OMIM ID: 608962 |
| Drug and gene relationship at DGIdb | |||
Expression of RHBDL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDL2 | 54933 | 1554897_s_at | -0.7398 | 0.4504 | |
| GSE26886 | RHBDL2 | 54933 | 1552502_s_at | -3.9339 | 0.0000 | |
| GSE45670 | RHBDL2 | 54933 | 1552502_s_at | -0.3909 | 0.2174 | |
| GSE53622 | RHBDL2 | 54933 | 131377 | -0.9449 | 0.0000 | |
| GSE53624 | RHBDL2 | 54933 | 702 | -1.0687 | 0.0000 | |
| GSE63941 | RHBDL2 | 54933 | 1554897_s_at | 1.7773 | 0.1743 | |
| GSE77861 | RHBDL2 | 54933 | 1554895_a_at | -0.3702 | 0.0478 | |
| GSE97050 | RHBDL2 | 54933 | A_23_P63432 | -0.0725 | 0.8554 | |
| SRP007169 | RHBDL2 | 54933 | RNAseq | -2.4237 | 0.0002 | |
| SRP008496 | RHBDL2 | 54933 | RNAseq | -2.4813 | 0.0000 | |
| SRP064894 | RHBDL2 | 54933 | RNAseq | -1.6666 | 0.0000 | |
| SRP133303 | RHBDL2 | 54933 | RNAseq | -0.8243 | 0.0001 | |
| SRP159526 | RHBDL2 | 54933 | RNAseq | -2.3545 | 0.0002 | |
| SRP193095 | RHBDL2 | 54933 | RNAseq | -1.2836 | 0.0000 | |
| SRP219564 | RHBDL2 | 54933 | RNAseq | -1.8860 | 0.0449 | |
| TCGA | RHBDL2 | 54933 | RNAseq | -0.0479 | 0.7862 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by RHBDL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHBDL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDL2 | 54933 | 2 | 4 | 24 | |
| GSE20123 | RHBDL2 | 54933 | 2 | 3 | 25 | |
| GSE43470 | RHBDL2 | 54933 | 7 | 2 | 34 | |
| GSE46452 | RHBDL2 | 54933 | 4 | 1 | 54 | |
| GSE47630 | RHBDL2 | 54933 | 8 | 4 | 28 | |
| GSE54993 | RHBDL2 | 54933 | 0 | 1 | 69 | |
| GSE54994 | RHBDL2 | 54933 | 13 | 2 | 38 | |
| GSE60625 | RHBDL2 | 54933 | 0 | 0 | 11 | |
| GSE74703 | RHBDL2 | 54933 | 6 | 1 | 29 | |
| GSE74704 | RHBDL2 | 54933 | 1 | 0 | 19 | |
| TCGA | RHBDL2 | 54933 | 14 | 16 | 66 |
Total number of gains: 57; Total number of losses: 34; Total Number of normals: 397.
Somatic mutations of RHBDL2:
Generating mutation plots.
Highly correlated genes for RHBDL2:
Showing top 20/955 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDL2 | RAB11FIP1 | 0.799573 | 5 | 0 | 5 |
| RHBDL2 | PRSS2 | 0.79633 | 5 | 0 | 5 |
| RHBDL2 | DSC2 | 0.776587 | 6 | 0 | 6 |
| RHBDL2 | ORMDL2 | 0.771323 | 4 | 0 | 4 |
| RHBDL2 | SPTLC1 | 0.768381 | 7 | 0 | 7 |
| RHBDL2 | GRHL1 | 0.765935 | 7 | 0 | 7 |
| RHBDL2 | RNF141 | 0.765173 | 6 | 0 | 6 |
| RHBDL2 | GPR157 | 0.764097 | 7 | 0 | 7 |
| RHBDL2 | BLNK | 0.759686 | 6 | 0 | 6 |
| RHBDL2 | S100A14 | 0.759544 | 7 | 0 | 7 |
| RHBDL2 | IL36A | 0.75754 | 7 | 0 | 7 |
| RHBDL2 | MFSD11 | 0.756824 | 4 | 0 | 4 |
| RHBDL2 | ACPP | 0.755873 | 7 | 0 | 7 |
| RHBDL2 | NCCRP1 | 0.754907 | 3 | 0 | 3 |
| RHBDL2 | SAMD9 | 0.754357 | 7 | 0 | 7 |
| RHBDL2 | GRHL3 | 0.750694 | 7 | 0 | 7 |
| RHBDL2 | FRMD4B | 0.747927 | 6 | 0 | 6 |
| RHBDL2 | CSTB | 0.747656 | 7 | 0 | 7 |
| RHBDL2 | TMEM79 | 0.74512 | 7 | 0 | 7 |
| RHBDL2 | GSKIP | 0.742829 | 6 | 0 | 6 |
For details and further investigation, click here
