| Full name: serine protease 16 | Alias Symbol: TSSP | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 10279 | HGNC ID: HGNC:9480 | Ensembl Gene: ENSG00000112812 | OMIM ID: 607169 |
| Drug and gene relationship at DGIdb | |||
Expression of PRSS16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRSS16 | 10279 | 208165_s_at | -0.0854 | 0.9374 | |
| GSE20347 | PRSS16 | 10279 | 208165_s_at | -0.5420 | 0.0209 | |
| GSE23400 | PRSS16 | 10279 | 208165_s_at | -0.0688 | 0.3298 | |
| GSE26886 | PRSS16 | 10279 | 208165_s_at | -1.2686 | 0.0000 | |
| GSE29001 | PRSS16 | 10279 | 208165_s_at | -0.2303 | 0.5980 | |
| GSE38129 | PRSS16 | 10279 | 208165_s_at | 0.1867 | 0.5326 | |
| GSE45670 | PRSS16 | 10279 | 208165_s_at | -0.0045 | 0.9881 | |
| GSE53622 | PRSS16 | 10279 | 83784 | -0.5248 | 0.0000 | |
| GSE53624 | PRSS16 | 10279 | 83784 | -0.6921 | 0.0000 | |
| GSE63941 | PRSS16 | 10279 | 208165_s_at | 2.6343 | 0.0030 | |
| GSE77861 | PRSS16 | 10279 | 208165_s_at | -0.7182 | 0.0278 | |
| GSE97050 | PRSS16 | 10279 | A_33_P3377649 | -0.0047 | 0.9916 | |
| SRP007169 | PRSS16 | 10279 | RNAseq | -0.3091 | 0.5672 | |
| SRP064894 | PRSS16 | 10279 | RNAseq | 0.0694 | 0.8632 | |
| SRP133303 | PRSS16 | 10279 | RNAseq | -0.4140 | 0.1609 | |
| SRP159526 | PRSS16 | 10279 | RNAseq | -0.2284 | 0.5576 | |
| SRP193095 | PRSS16 | 10279 | RNAseq | -0.7002 | 0.0015 | |
| SRP219564 | PRSS16 | 10279 | RNAseq | 0.2097 | 0.8285 | |
| TCGA | PRSS16 | 10279 | RNAseq | -0.1310 | 0.3141 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PRSS16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRSS16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRSS16 | 10279 | 4 | 2 | 24 | |
| GSE20123 | PRSS16 | 10279 | 4 | 2 | 24 | |
| GSE43470 | PRSS16 | 10279 | 5 | 0 | 38 | |
| GSE46452 | PRSS16 | 10279 | 1 | 10 | 48 | |
| GSE47630 | PRSS16 | 10279 | 8 | 4 | 28 | |
| GSE54993 | PRSS16 | 10279 | 2 | 1 | 67 | |
| GSE54994 | PRSS16 | 10279 | 11 | 4 | 38 | |
| GSE60625 | PRSS16 | 10279 | 0 | 1 | 10 | |
| GSE74703 | PRSS16 | 10279 | 5 | 0 | 31 | |
| GSE74704 | PRSS16 | 10279 | 0 | 1 | 19 | |
| TCGA | PRSS16 | 10279 | 15 | 20 | 61 |
Total number of gains: 55; Total number of losses: 45; Total Number of normals: 388.
Somatic mutations of PRSS16:
Generating mutation plots.
Highly correlated genes for PRSS16:
Showing top 20/342 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRSS16 | MFSD2B | 0.723257 | 3 | 0 | 3 |
| PRSS16 | SFTPB | 0.695047 | 4 | 0 | 4 |
| PRSS16 | AP4B1 | 0.684479 | 3 | 0 | 3 |
| PRSS16 | E2F2 | 0.682299 | 3 | 0 | 3 |
| PRSS16 | AIF1L | 0.669725 | 7 | 0 | 7 |
| PRSS16 | KRTAP20-1 | 0.667981 | 3 | 0 | 3 |
| PRSS16 | VSIG10L | 0.666604 | 5 | 0 | 5 |
| PRSS16 | C6orf132 | 0.664957 | 7 | 0 | 7 |
| PRSS16 | ACTL9 | 0.654327 | 3 | 0 | 3 |
| PRSS16 | CD164L2 | 0.653992 | 3 | 0 | 3 |
| PRSS16 | SLC25A51 | 0.653875 | 3 | 0 | 3 |
| PRSS16 | CAPG | 0.649905 | 6 | 0 | 4 |
| PRSS16 | CHTF8 | 0.646809 | 3 | 0 | 3 |
| PRSS16 | VAMP8 | 0.644877 | 8 | 0 | 8 |
| PRSS16 | CLDN24 | 0.640091 | 3 | 0 | 3 |
| PRSS16 | MIR205HG | 0.639722 | 4 | 0 | 3 |
| PRSS16 | DMKN | 0.638583 | 4 | 0 | 4 |
| PRSS16 | RPS3 | 0.637615 | 3 | 0 | 3 |
| PRSS16 | RBM20 | 0.637327 | 3 | 0 | 3 |
| PRSS16 | ESYT3 | 0.637155 | 3 | 0 | 3 |
For details and further investigation, click here
