| Full name: dermokine | Alias Symbol: ZD52F10 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 93099 | HGNC ID: HGNC:25063 | Ensembl Gene: ENSG00000161249 | OMIM ID: 617211 |
| Drug and gene relationship at DGIdb | |||
Expression of DMKN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMKN | 93099 | 226926_at | -0.6972 | 0.6523 | |
| GSE26886 | DMKN | 93099 | 226926_at | -2.7153 | 0.0000 | |
| GSE45670 | DMKN | 93099 | 226926_at | 0.6387 | 0.2356 | |
| GSE53622 | DMKN | 93099 | 10659 | -0.6996 | 0.0146 | |
| GSE53624 | DMKN | 93099 | 10659 | -0.9961 | 0.0000 | |
| GSE63941 | DMKN | 93099 | 226926_at | 3.5074 | 0.0018 | |
| GSE77861 | DMKN | 93099 | 226926_at | -0.5349 | 0.3117 | |
| GSE97050 | DMKN | 93099 | A_33_P3246885 | 0.9999 | 0.1659 | |
| SRP007169 | DMKN | 93099 | RNAseq | -2.4568 | 0.0000 | |
| SRP008496 | DMKN | 93099 | RNAseq | -2.6486 | 0.0000 | |
| SRP064894 | DMKN | 93099 | RNAseq | -0.0421 | 0.9269 | |
| SRP133303 | DMKN | 93099 | RNAseq | -0.9012 | 0.0096 | |
| SRP159526 | DMKN | 93099 | RNAseq | -0.8369 | 0.1197 | |
| SRP193095 | DMKN | 93099 | RNAseq | -1.2492 | 0.0001 | |
| SRP219564 | DMKN | 93099 | RNAseq | -0.8154 | 0.4026 | |
| TCGA | DMKN | 93099 | RNAseq | 0.4837 | 0.0227 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by DMKN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMKN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMKN | 93099 | 6 | 4 | 20 | |
| GSE20123 | DMKN | 93099 | 6 | 3 | 21 | |
| GSE43470 | DMKN | 93099 | 3 | 7 | 33 | |
| GSE46452 | DMKN | 93099 | 48 | 1 | 10 | |
| GSE47630 | DMKN | 93099 | 9 | 5 | 26 | |
| GSE54993 | DMKN | 93099 | 17 | 3 | 50 | |
| GSE54994 | DMKN | 93099 | 8 | 9 | 36 | |
| GSE60625 | DMKN | 93099 | 9 | 0 | 2 | |
| GSE74703 | DMKN | 93099 | 3 | 4 | 29 | |
| GSE74704 | DMKN | 93099 | 6 | 1 | 13 | |
| TCGA | DMKN | 93099 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of DMKN:
Generating mutation plots.
Highly correlated genes for DMKN:
Showing top 20/809 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMKN | LYPD3 | 0.782832 | 7 | 0 | 7 |
| DMKN | CTNNBIP1 | 0.763524 | 3 | 0 | 3 |
| DMKN | PGLYRP3 | 0.755498 | 3 | 0 | 3 |
| DMKN | DSC2 | 0.755057 | 8 | 0 | 7 |
| DMKN | ELOVL1 | 0.733196 | 3 | 0 | 3 |
| DMKN | TMEM134 | 0.732908 | 5 | 0 | 4 |
| DMKN | CWH43 | 0.731502 | 5 | 0 | 5 |
| DMKN | KRT80 | 0.72936 | 8 | 0 | 8 |
| DMKN | KLK7 | 0.728936 | 7 | 0 | 7 |
| DMKN | GRHL2 | 0.727439 | 3 | 0 | 3 |
| DMKN | KLK8 | 0.726675 | 8 | 0 | 7 |
| DMKN | E2F2 | 0.725345 | 4 | 0 | 4 |
| DMKN | GRHL1 | 0.72284 | 7 | 0 | 7 |
| DMKN | DSG3 | 0.71929 | 8 | 0 | 7 |
| DMKN | TGM1 | 0.717481 | 8 | 0 | 7 |
| DMKN | HOOK1 | 0.716698 | 5 | 0 | 4 |
| DMKN | SRD5A1 | 0.716469 | 4 | 0 | 4 |
| DMKN | PRRG4 | 0.716041 | 7 | 0 | 7 |
| DMKN | PGM2 | 0.716016 | 6 | 0 | 6 |
| DMKN | KRTAP20-3 | 0.715916 | 3 | 0 | 3 |
For details and further investigation, click here
