| Full name: actin like 9 | Alias Symbol: MGC33407 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 284382 | HGNC ID: HGNC:28494 | Ensembl Gene: ENSG00000181786 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ACTL9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTL9 | 284382 | 243208_x_at | -0.0970 | 0.6776 | |
| GSE26886 | ACTL9 | 284382 | 243208_x_at | -0.0112 | 0.9377 | |
| GSE45670 | ACTL9 | 284382 | 243208_x_at | -0.2004 | 0.0429 | |
| GSE53622 | ACTL9 | 284382 | 29661 | -0.2563 | 0.0739 | |
| GSE53624 | ACTL9 | 284382 | 29661 | -1.3304 | 0.0000 | |
| GSE63941 | ACTL9 | 284382 | 243208_x_at | 0.0883 | 0.5288 | |
| GSE77861 | ACTL9 | 284382 | 243208_x_at | -0.3215 | 0.0244 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ACTL9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTL9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTL9 | 284382 | 4 | 3 | 23 | |
| GSE20123 | ACTL9 | 284382 | 3 | 2 | 25 | |
| GSE43470 | ACTL9 | 284382 | 2 | 5 | 36 | |
| GSE46452 | ACTL9 | 284382 | 47 | 1 | 11 | |
| GSE47630 | ACTL9 | 284382 | 5 | 7 | 28 | |
| GSE54993 | ACTL9 | 284382 | 16 | 2 | 52 | |
| GSE54994 | ACTL9 | 284382 | 6 | 14 | 33 | |
| GSE60625 | ACTL9 | 284382 | 9 | 0 | 2 | |
| GSE74703 | ACTL9 | 284382 | 2 | 4 | 30 | |
| GSE74704 | ACTL9 | 284382 | 0 | 2 | 18 | |
| TCGA | ACTL9 | 284382 | 10 | 19 | 67 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of ACTL9:
Generating mutation plots.
Highly correlated genes for ACTL9:
Showing top 20/138 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTL9 | PTK6 | 0.676365 | 3 | 0 | 3 |
| ACTL9 | LINC00567 | 0.667211 | 3 | 0 | 3 |
| ACTL9 | PHYHIP | 0.663493 | 3 | 0 | 3 |
| ACTL9 | EHD3 | 0.6609 | 3 | 0 | 3 |
| ACTL9 | PRSS16 | 0.654327 | 3 | 0 | 3 |
| ACTL9 | SERPINB6 | 0.65291 | 3 | 0 | 3 |
| ACTL9 | CAST | 0.648521 | 3 | 0 | 3 |
| ACTL9 | PLEKHN1 | 0.643239 | 3 | 0 | 3 |
| ACTL9 | S100A16 | 0.643101 | 3 | 0 | 3 |
| ACTL9 | MAPK3 | 0.636362 | 3 | 0 | 3 |
| ACTL9 | ALDH9A1 | 0.632024 | 4 | 0 | 4 |
| ACTL9 | C1orf116 | 0.631869 | 3 | 0 | 3 |
| ACTL9 | ADAMTSL4 | 0.631675 | 3 | 0 | 3 |
| ACTL9 | CXCL17 | 0.626613 | 4 | 0 | 3 |
| ACTL9 | PPP1R3C | 0.624595 | 3 | 0 | 3 |
| ACTL9 | SLURP1 | 0.624054 | 3 | 0 | 3 |
| ACTL9 | CYSRT1 | 0.621858 | 3 | 0 | 3 |
| ACTL9 | VSIG10L | 0.618862 | 3 | 0 | 3 |
| ACTL9 | CXCR2 | 0.618332 | 3 | 0 | 3 |
| ACTL9 | KIAA1211L | 0.613456 | 4 | 0 | 4 |
For details and further investigation, click here
