| Full name: coiled-coil domain containing 18 | Alias Symbol: NY-SAR-41 | ||
| Type: protein-coding gene | Cytoband: 1p22.1 | ||
| Entrez ID: 343099 | HGNC ID: HGNC:30370 | Ensembl Gene: ENSG00000122483 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC18 | 343099 | 232362_at | 0.6162 | 0.1004 | |
| GSE26886 | CCDC18 | 343099 | 232362_at | 0.0405 | 0.8902 | |
| GSE45670 | CCDC18 | 343099 | 232362_at | 0.5115 | 0.0133 | |
| GSE53622 | CCDC18 | 343099 | 41336 | 0.6266 | 0.0000 | |
| GSE53624 | CCDC18 | 343099 | 41336 | 0.6950 | 0.0000 | |
| GSE63941 | CCDC18 | 343099 | 232362_at | 0.1055 | 0.8620 | |
| GSE77861 | CCDC18 | 343099 | 232362_at | 0.1307 | 0.1752 | |
| GSE97050 | CCDC18 | 343099 | A_33_P3327165 | 0.5114 | 0.1782 | |
| SRP007169 | CCDC18 | 343099 | RNAseq | 0.6306 | 0.2518 | |
| SRP008496 | CCDC18 | 343099 | RNAseq | 0.6562 | 0.0758 | |
| SRP064894 | CCDC18 | 343099 | RNAseq | 1.0914 | 0.0004 | |
| SRP133303 | CCDC18 | 343099 | RNAseq | 0.7176 | 0.0000 | |
| SRP159526 | CCDC18 | 343099 | RNAseq | 0.2596 | 0.6232 | |
| SRP193095 | CCDC18 | 343099 | RNAseq | 0.5837 | 0.0001 | |
| SRP219564 | CCDC18 | 343099 | RNAseq | 0.4837 | 0.1947 | |
| TCGA | CCDC18 | 343099 | RNAseq | 0.5915 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CCDC18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC18 | 343099 | 0 | 8 | 22 | |
| GSE20123 | CCDC18 | 343099 | 0 | 8 | 22 | |
| GSE43470 | CCDC18 | 343099 | 2 | 6 | 35 | |
| GSE46452 | CCDC18 | 343099 | 1 | 1 | 57 | |
| GSE47630 | CCDC18 | 343099 | 8 | 5 | 27 | |
| GSE54993 | CCDC18 | 343099 | 0 | 1 | 69 | |
| GSE54994 | CCDC18 | 343099 | 6 | 3 | 44 | |
| GSE60625 | CCDC18 | 343099 | 0 | 0 | 11 | |
| GSE74703 | CCDC18 | 343099 | 1 | 5 | 30 | |
| GSE74704 | CCDC18 | 343099 | 0 | 5 | 15 | |
| TCGA | CCDC18 | 343099 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of CCDC18:
Generating mutation plots.
Highly correlated genes for CCDC18:
Showing top 20/1172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC18 | FZD6 | 0.824543 | 4 | 0 | 4 |
| CCDC18 | ARMC8 | 0.771053 | 3 | 0 | 3 |
| CCDC18 | SCARB1 | 0.754885 | 3 | 0 | 3 |
| CCDC18 | CCDC127 | 0.746675 | 3 | 0 | 3 |
| CCDC18 | PSAP | 0.744148 | 3 | 0 | 3 |
| CCDC18 | UXS1 | 0.743772 | 4 | 0 | 4 |
| CCDC18 | DSCC1 | 0.743477 | 4 | 0 | 4 |
| CCDC18 | KNTC1 | 0.73865 | 6 | 0 | 6 |
| CCDC18 | HAUS7 | 0.734889 | 3 | 0 | 3 |
| CCDC18 | ZNF518B | 0.733964 | 4 | 0 | 4 |
| CCDC18 | C1orf112 | 0.731998 | 4 | 0 | 4 |
| CCDC18 | PTK2 | 0.72882 | 6 | 0 | 6 |
| CCDC18 | RBM17 | 0.72854 | 3 | 0 | 3 |
| CCDC18 | MTERF3 | 0.728388 | 3 | 0 | 3 |
| CCDC18 | SET | 0.726897 | 3 | 0 | 3 |
| CCDC18 | ZNF284 | 0.722944 | 3 | 0 | 3 |
| CCDC18 | SAMD1 | 0.722172 | 4 | 0 | 4 |
| CCDC18 | MTBP | 0.719614 | 5 | 0 | 5 |
| CCDC18 | PDE7A | 0.717836 | 6 | 0 | 6 |
| CCDC18 | SOCS4 | 0.717757 | 4 | 0 | 4 |
For details and further investigation, click here
