| Full name: ADP ribosylation factor related protein 1 | Alias Symbol: ARP|Arp1|ARL18 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 10139 | HGNC ID: HGNC:662 | Ensembl Gene: ENSG00000101246 | OMIM ID: 604699 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARFRP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARFRP1 | 10139 | 203174_s_at | 0.3091 | 0.1270 | |
| GSE20347 | ARFRP1 | 10139 | 203174_s_at | -0.0121 | 0.8984 | |
| GSE23400 | ARFRP1 | 10139 | 203174_s_at | 0.0029 | 0.9564 | |
| GSE26886 | ARFRP1 | 10139 | 203174_s_at | -0.1609 | 0.3192 | |
| GSE29001 | ARFRP1 | 10139 | 203174_s_at | 0.1125 | 0.6562 | |
| GSE38129 | ARFRP1 | 10139 | 203174_s_at | -0.0276 | 0.7841 | |
| GSE45670 | ARFRP1 | 10139 | 203174_s_at | 0.0259 | 0.8494 | |
| GSE53622 | ARFRP1 | 10139 | 5506 | -0.2178 | 0.0007 | |
| GSE53624 | ARFRP1 | 10139 | 5506 | 0.1283 | 0.0608 | |
| GSE63941 | ARFRP1 | 10139 | 203174_s_at | -0.0693 | 0.8280 | |
| GSE77861 | ARFRP1 | 10139 | 203174_s_at | -0.0786 | 0.6056 | |
| GSE97050 | ARFRP1 | 10139 | A_33_P3242748 | 0.1325 | 0.6807 | |
| SRP007169 | ARFRP1 | 10139 | RNAseq | 0.9892 | 0.1842 | |
| SRP064894 | ARFRP1 | 10139 | RNAseq | 0.6803 | 0.0180 | |
| SRP133303 | ARFRP1 | 10139 | RNAseq | 0.1390 | 0.3944 | |
| SRP159526 | ARFRP1 | 10139 | RNAseq | -0.1015 | 0.7361 | |
| SRP193095 | ARFRP1 | 10139 | RNAseq | 0.0802 | 0.5056 | |
| SRP219564 | ARFRP1 | 10139 | RNAseq | 0.4323 | 0.2286 | |
| TCGA | ARFRP1 | 10139 | RNAseq | 0.0896 | 0.1334 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARFRP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARFRP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARFRP1 | 10139 | 14 | 2 | 14 | |
| GSE20123 | ARFRP1 | 10139 | 14 | 2 | 14 | |
| GSE43470 | ARFRP1 | 10139 | 11 | 1 | 31 | |
| GSE46452 | ARFRP1 | 10139 | 35 | 0 | 24 | |
| GSE47630 | ARFRP1 | 10139 | 25 | 1 | 14 | |
| GSE54993 | ARFRP1 | 10139 | 0 | 17 | 53 | |
| GSE54994 | ARFRP1 | 10139 | 29 | 0 | 24 | |
| GSE60625 | ARFRP1 | 10139 | 0 | 0 | 11 | |
| GSE74703 | ARFRP1 | 10139 | 10 | 0 | 26 | |
| GSE74704 | ARFRP1 | 10139 | 11 | 0 | 9 | |
| TCGA | ARFRP1 | 10139 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.
Somatic mutations of ARFRP1:
Generating mutation plots.
Highly correlated genes for ARFRP1:
Showing top 20/369 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARFRP1 | CCS | 0.826278 | 3 | 0 | 3 |
| ARFRP1 | IGF2R | 0.817078 | 3 | 0 | 3 |
| ARFRP1 | PUF60 | 0.808294 | 3 | 0 | 3 |
| ARFRP1 | SLC39A3 | 0.782568 | 3 | 0 | 3 |
| ARFRP1 | USP36 | 0.774701 | 3 | 0 | 3 |
| ARFRP1 | TGIF2 | 0.762416 | 3 | 0 | 3 |
| ARFRP1 | PDRG1 | 0.757266 | 3 | 0 | 3 |
| ARFRP1 | NONO | 0.755269 | 3 | 0 | 3 |
| ARFRP1 | MTHFSD | 0.753513 | 3 | 0 | 3 |
| ARFRP1 | PLCG1 | 0.751553 | 5 | 0 | 5 |
| ARFRP1 | C1orf35 | 0.750298 | 3 | 0 | 3 |
| ARFRP1 | ZNF683 | 0.748561 | 3 | 0 | 3 |
| ARFRP1 | RAC3 | 0.745617 | 3 | 0 | 3 |
| ARFRP1 | GANAB | 0.744386 | 3 | 0 | 3 |
| ARFRP1 | OGG1 | 0.741768 | 3 | 0 | 3 |
| ARFRP1 | IGSF6 | 0.731317 | 3 | 0 | 3 |
| ARFRP1 | SLC25A29 | 0.726479 | 3 | 0 | 3 |
| ARFRP1 | ABCD4 | 0.725033 | 3 | 0 | 3 |
| ARFRP1 | BLOC1S3 | 0.721535 | 3 | 0 | 3 |
| ARFRP1 | ZNF830 | 0.719732 | 3 | 0 | 3 |
For details and further investigation, click here
