MS4A14

 

Full name: membrane spanning 4-domains A14 Alias Symbol: NYD-SP21|FLJ32856|DKFZp434H092
Type: protein-coding gene Cytoband: 11q12.2
Entrez ID: 84689 HGNC ID: HGNC:30706 Ensembl Gene:  OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of MS4A14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MS4A14 84689 229510_at 0.2811 0.4428
GSE26886 MS4A14 84689 229510_at -0.0129 0.9190
GSE45670 MS4A14 84689 229510_at 0.0943 0.6794
GSE63941 MS4A14 84689 229510_at 0.1319 0.2438
GSE77861 MS4A14 84689 229510_at 0.0489 0.5116
GSE97050 MS4A14 84689 A_33_P3290577 0.4911 0.2318
SRP064894 MS4A14 84689 RNAseq 1.0673 0.0036
SRP133303 MS4A14 84689 RNAseq 0.6539 0.0663
SRP159526 MS4A14 84689 RNAseq -0.1071 0.7782
SRP219564 MS4A14 84689 RNAseq 1.0984 0.0523
TCGA MS4A14 84689 RNAseq 0.1896 0.4097

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by MS4A14 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of MS4A14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MS4A14 84689 2 4 24
GSE20123 MS4A14 84689 2 4 24
GSE43470 MS4A14 84689 2 5 36
GSE46452 MS4A14 84689 8 4 47
GSE47630 MS4A14 84689 3 8 29
GSE54993 MS4A14 84689 3 0 67
GSE54994 MS4A14 84689 5 5 43
GSE60625 MS4A14 84689 0 3 8
GSE74703 MS4A14 84689 2 3 31
GSE74704 MS4A14 84689 2 3 15
TCGA MS4A14 84689 14 10 72

Total number of gains: 43; Total number of losses: 49; Total Number of normals: 396.  


 

Somatic mutations of MS4A14:

 

Generating mutation plots.

 

Highly correlated genes for MS4A14:

 

Showing top 20/96 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MS4A14ITGAX0.757527303
MS4A14PSAP0.754333303
MS4A14PSTPIP20.73335303
MS4A14CD2480.71583303
MS4A14TRPV20.712705303
MS4A14HERC50.706154303
MS4A14LCP20.699897303
MS4A14CMTM30.681473303
MS4A14C1QB0.680275403
MS4A14PUS30.672976303
MS4A14CTSZ0.671049303
MS4A14PREX10.670898303
MS4A14MS4A70.669449404
MS4A14GLIPR10.668818303
MS4A14WDR120.663843303
MS4A14TAP10.65767403
MS4A14C5orf150.656979303
MS4A14C1QA0.650461404
MS4A14TNFRSF1B0.649408403
MS4A14LILRB10.64683504

For details and further investigation, click here