| Full name: keratin associated protein 8-1 | Alias Symbol: KAP8.1 | ||
| Type: protein-coding gene | Cytoband: 21q22.1 | ||
| Entrez ID: 337879 | HGNC ID: HGNC:18935 | Ensembl Gene: ENSG00000183640 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP8-1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTAP8-1 | 337879 | 1564974_at | 0.0726 | 0.7734 | |
| GSE26886 | KRTAP8-1 | 337879 | 1564974_at | -0.1115 | 0.3747 | |
| GSE45670 | KRTAP8-1 | 337879 | 1564974_at | 0.0467 | 0.7128 | |
| GSE53622 | KRTAP8-1 | 337879 | 43839 | -0.2145 | 0.0424 | |
| GSE53624 | KRTAP8-1 | 337879 | 43839 | -0.0917 | 0.2974 | |
| GSE63941 | KRTAP8-1 | 337879 | 1564974_at | 0.4335 | 0.0133 | |
| GSE77861 | KRTAP8-1 | 337879 | 1564974_at | -0.0522 | 0.6651 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP8-1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP8-1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP8-1 | 337879 | 2 | 9 | 19 | |
| GSE20123 | KRTAP8-1 | 337879 | 2 | 9 | 19 | |
| GSE43470 | KRTAP8-1 | 337879 | 2 | 9 | 32 | |
| GSE46452 | KRTAP8-1 | 337879 | 1 | 21 | 37 | |
| GSE47630 | KRTAP8-1 | 337879 | 6 | 17 | 17 | |
| GSE54993 | KRTAP8-1 | 337879 | 9 | 1 | 60 | |
| GSE54994 | KRTAP8-1 | 337879 | 1 | 9 | 43 | |
| GSE60625 | KRTAP8-1 | 337879 | 0 | 0 | 11 | |
| GSE74703 | KRTAP8-1 | 337879 | 2 | 6 | 28 | |
| GSE74704 | KRTAP8-1 | 337879 | 2 | 6 | 12 |
Total number of gains: 27; Total number of losses: 87; Total Number of normals: 278.
Somatic mutations of KRTAP8-1:
Generating mutation plots.
Highly correlated genes for KRTAP8-1:
Showing top 20/89 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP8-1 | CD101 | 0.709799 | 3 | 0 | 3 |
| KRTAP8-1 | WDR11-AS1 | 0.691044 | 4 | 0 | 4 |
| KRTAP8-1 | TMEM225 | 0.65575 | 4 | 0 | 4 |
| KRTAP8-1 | PRB1 | 0.631058 | 3 | 0 | 3 |
| KRTAP8-1 | STAU2-AS1 | 0.628614 | 5 | 0 | 4 |
| KRTAP8-1 | GNAO1 | 0.627321 | 3 | 0 | 3 |
| KRTAP8-1 | C19orf84 | 0.626201 | 5 | 0 | 3 |
| KRTAP8-1 | SETD5 | 0.624074 | 3 | 0 | 3 |
| KRTAP8-1 | COL9A2 | 0.61691 | 3 | 0 | 3 |
| KRTAP8-1 | ANKRD53 | 0.613176 | 3 | 0 | 3 |
| KRTAP8-1 | KCNIP2 | 0.61308 | 4 | 0 | 3 |
| KRTAP8-1 | MC2R | 0.611687 | 3 | 0 | 3 |
| KRTAP8-1 | GLP1R | 0.610293 | 3 | 0 | 3 |
| KRTAP8-1 | NMUR2 | 0.605012 | 4 | 0 | 4 |
| KRTAP8-1 | FGA | 0.604699 | 5 | 0 | 4 |
| KRTAP8-1 | PRCD | 0.601716 | 3 | 0 | 3 |
| KRTAP8-1 | ACACB | 0.598703 | 4 | 0 | 3 |
| KRTAP8-1 | RNASE2 | 0.595396 | 4 | 0 | 3 |
| KRTAP8-1 | NAT2 | 0.592422 | 3 | 0 | 3 |
| KRTAP8-1 | SNX32 | 0.59239 | 4 | 0 | 4 |
For details and further investigation, click here
