GALM

 

Full name: galactose mutarotase Alias Symbol: 
Type: protein-coding gene Cytoband: 2p22.1
Entrez ID: 130589 HGNC ID: HGNC:24063 Ensembl Gene: ENSG00000143891 OMIM ID: 137030
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of GALM:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GALM 130589 235256_s_at -0.0301 0.9758
GSE26886 GALM 130589 234974_at 0.5413 0.0645
GSE45670 GALM 130589 234974_at -0.1605 0.2891
GSE53622 GALM 130589 54156 0.1773 0.1979
GSE53624 GALM 130589 14901 0.0772 0.6123
GSE63941 GALM 130589 235256_s_at -1.5984 0.2994
GSE77861 GALM 130589 234974_at -0.1731 0.1404
GSE97050 GALM 130589 A_24_P212539 0.1009 0.6138
SRP007169 GALM 130589 RNAseq 1.1899 0.1006
SRP008496 GALM 130589 RNAseq 0.4171 0.3896
SRP064894 GALM 130589 RNAseq 0.6226 0.0181
SRP133303 GALM 130589 RNAseq 0.1749 0.2767
SRP159526 GALM 130589 RNAseq -0.1503 0.7200
SRP193095 GALM 130589 RNAseq -0.3223 0.2828
SRP219564 GALM 130589 RNAseq -0.0155 0.9725
TCGA GALM 130589 RNAseq -0.2810 0.0315

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GALM expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GALM:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GALM 130589 11 1 18
GSE20123 GALM 130589 10 1 19
GSE43470 GALM 130589 3 0 40
GSE46452 GALM 130589 1 4 54
GSE47630 GALM 130589 7 0 33
GSE54993 GALM 130589 0 5 65
GSE54994 GALM 130589 10 0 43
GSE60625 GALM 130589 0 3 8
GSE74703 GALM 130589 3 0 33
GSE74704 GALM 130589 9 1 10
TCGA GALM 130589 35 3 58

Total number of gains: 89; Total number of losses: 18; Total Number of normals: 381.  


 

Somatic mutations of GALM:

 

Generating mutation plots.

 

Highly correlated genes for GALM:

 

Showing top 20/372 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GALMTSNARE10.7621303
GALMRGS180.744091303
GALMTSPAN310.739815303
GALMSTX180.732657303
GALMCCDC970.722577303
GALMTMEM106A0.719705303
GALMCCL220.712101303
GALMCFHR30.710825303
GALMPCNP0.709587303
GALMSNCA0.709451303
GALMRAMP10.707961303
GALMKIAA15860.695396303
GALMNACC20.694627303
GALMGNAS0.694426303
GALMMYL6B0.692123303
GALMBEGAIN0.691194403
GALMEPAS10.685961303
GALMKCNJ20.685652303
GALMNCKIPSD0.684752403
GALMTSPAN90.683316303

For details and further investigation, click here