| Full name: ankyrin repeat and sterile alpha motif domain containing 3 | Alias Symbol: KIAA1977|FLJ32345|FLJ32767 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 124401 | HGNC ID: HGNC:29422 | Ensembl Gene: ENSG00000168096 | OMIM ID: 617310 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKS3 | 124401 | 227303_at | 0.2613 | 0.4616 | |
| GSE26886 | ANKS3 | 124401 | 227303_at | 0.5868 | 0.0004 | |
| GSE45670 | ANKS3 | 124401 | 227303_at | 0.0314 | 0.8113 | |
| GSE53622 | ANKS3 | 124401 | 80456 | 0.1910 | 0.0096 | |
| GSE53624 | ANKS3 | 124401 | 80456 | 0.3589 | 0.0000 | |
| GSE63941 | ANKS3 | 124401 | 227303_at | -0.8319 | 0.0010 | |
| GSE77861 | ANKS3 | 124401 | 227303_at | 0.0416 | 0.7957 | |
| GSE97050 | ANKS3 | 124401 | A_33_P3211153 | -0.1590 | 0.5619 | |
| SRP007169 | ANKS3 | 124401 | RNAseq | 0.1200 | 0.8529 | |
| SRP064894 | ANKS3 | 124401 | RNAseq | 0.6569 | 0.0338 | |
| SRP133303 | ANKS3 | 124401 | RNAseq | 0.1365 | 0.4825 | |
| SRP159526 | ANKS3 | 124401 | RNAseq | 0.1527 | 0.6438 | |
| SRP193095 | ANKS3 | 124401 | RNAseq | 0.5114 | 0.0000 | |
| SRP219564 | ANKS3 | 124401 | RNAseq | 0.5002 | 0.3325 | |
| TCGA | ANKS3 | 124401 | RNAseq | -0.1088 | 0.0946 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKS3 | 124401 | 6 | 5 | 19 | |
| GSE20123 | ANKS3 | 124401 | 6 | 4 | 20 | |
| GSE43470 | ANKS3 | 124401 | 4 | 6 | 33 | |
| GSE46452 | ANKS3 | 124401 | 38 | 1 | 20 | |
| GSE47630 | ANKS3 | 124401 | 13 | 6 | 21 | |
| GSE54993 | ANKS3 | 124401 | 3 | 5 | 62 | |
| GSE54994 | ANKS3 | 124401 | 5 | 9 | 39 | |
| GSE60625 | ANKS3 | 124401 | 4 | 0 | 7 | |
| GSE74703 | ANKS3 | 124401 | 4 | 4 | 28 | |
| GSE74704 | ANKS3 | 124401 | 3 | 2 | 15 | |
| TCGA | ANKS3 | 124401 | 19 | 13 | 64 |
Total number of gains: 105; Total number of losses: 55; Total Number of normals: 328.
Somatic mutations of ANKS3:
Generating mutation plots.
Highly correlated genes for ANKS3:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKS3 | ILDR2 | 0.798993 | 3 | 0 | 3 |
| ANKS3 | COX7A1 | 0.775081 | 3 | 0 | 3 |
| ANKS3 | RILPL1 | 0.744464 | 3 | 0 | 3 |
| ANKS3 | DPT | 0.743831 | 3 | 0 | 3 |
| ANKS3 | DEGS1 | 0.734381 | 3 | 0 | 3 |
| ANKS3 | CD248 | 0.726137 | 3 | 0 | 3 |
| ANKS3 | DIXDC1 | 0.723432 | 3 | 0 | 3 |
| ANKS3 | TSNARE1 | 0.719616 | 4 | 0 | 4 |
| ANKS3 | ARMC9 | 0.716321 | 3 | 0 | 3 |
| ANKS3 | PTTG1IP | 0.71595 | 3 | 0 | 3 |
| ANKS3 | KLHL24 | 0.713307 | 3 | 0 | 3 |
| ANKS3 | MRPS26 | 0.713221 | 3 | 0 | 3 |
| ANKS3 | COPZ2 | 0.712215 | 3 | 0 | 3 |
| ANKS3 | GNPAT | 0.710841 | 3 | 0 | 3 |
| ANKS3 | CCNT1 | 0.707122 | 3 | 0 | 3 |
| ANKS3 | C20orf194 | 0.706873 | 3 | 0 | 3 |
| ANKS3 | LSM10 | 0.702943 | 4 | 0 | 4 |
| ANKS3 | NPHP3 | 0.699226 | 3 | 0 | 3 |
| ANKS3 | CTXN1 | 0.698522 | 5 | 0 | 5 |
| ANKS3 | ZBTB4 | 0.696385 | 3 | 0 | 3 |
For details and further investigation, click here
