| Full name: chromosome 12 open reading frame 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p13.32 | ||
| Entrez ID: 57102 | HGNC ID: HGNC:1184 | Ensembl Gene: ENSG00000047621 | OMIM ID: 616082 |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf4 | 57102 | 222613_at | -0.2160 | 0.4825 | |
| GSE20347 | C12orf4 | 57102 | 218374_s_at | 0.5218 | 0.0063 | |
| GSE23400 | C12orf4 | 57102 | 218374_s_at | 0.4264 | 0.0000 | |
| GSE26886 | C12orf4 | 57102 | 222613_at | -0.0758 | 0.8452 | |
| GSE29001 | C12orf4 | 57102 | 218374_s_at | 0.3984 | 0.3496 | |
| GSE38129 | C12orf4 | 57102 | 218374_s_at | 0.4289 | 0.0029 | |
| GSE45670 | C12orf4 | 57102 | 222613_at | 0.4284 | 0.0001 | |
| GSE53622 | C12orf4 | 57102 | 99285 | 0.3381 | 0.0000 | |
| GSE53624 | C12orf4 | 57102 | 99285 | 0.6077 | 0.0000 | |
| GSE63941 | C12orf4 | 57102 | 218374_s_at | 0.4085 | 0.5002 | |
| GSE77861 | C12orf4 | 57102 | 222613_at | 0.2137 | 0.6749 | |
| GSE97050 | C12orf4 | 57102 | A_23_P25433 | 0.4044 | 0.1980 | |
| SRP007169 | C12orf4 | 57102 | RNAseq | 0.7153 | 0.1470 | |
| SRP008496 | C12orf4 | 57102 | RNAseq | 0.6457 | 0.0481 | |
| SRP064894 | C12orf4 | 57102 | RNAseq | 0.0466 | 0.7241 | |
| SRP133303 | C12orf4 | 57102 | RNAseq | 0.4319 | 0.0029 | |
| SRP159526 | C12orf4 | 57102 | RNAseq | -0.2178 | 0.3851 | |
| SRP193095 | C12orf4 | 57102 | RNAseq | -0.1676 | 0.1241 | |
| SRP219564 | C12orf4 | 57102 | RNAseq | -0.0671 | 0.8132 | |
| TCGA | C12orf4 | 57102 | RNAseq | 0.1011 | 0.1218 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C12orf4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf4 | 57102 | 6 | 4 | 20 | |
| GSE20123 | C12orf4 | 57102 | 6 | 4 | 20 | |
| GSE43470 | C12orf4 | 57102 | 10 | 3 | 30 | |
| GSE46452 | C12orf4 | 57102 | 10 | 1 | 48 | |
| GSE47630 | C12orf4 | 57102 | 12 | 2 | 26 | |
| GSE54993 | C12orf4 | 57102 | 1 | 10 | 59 | |
| GSE54994 | C12orf4 | 57102 | 10 | 2 | 41 | |
| GSE60625 | C12orf4 | 57102 | 0 | 1 | 10 | |
| GSE74703 | C12orf4 | 57102 | 9 | 2 | 25 | |
| GSE74704 | C12orf4 | 57102 | 4 | 2 | 14 | |
| TCGA | C12orf4 | 57102 | 40 | 6 | 50 |
Total number of gains: 108; Total number of losses: 37; Total Number of normals: 343.
Somatic mutations of C12orf4:
Generating mutation plots.
Highly correlated genes for C12orf4:
Showing top 20/630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf4 | STAMBPL1 | 0.798567 | 3 | 0 | 3 |
| C12orf4 | NHS | 0.774271 | 3 | 0 | 3 |
| C12orf4 | ANKRD49 | 0.729254 | 3 | 0 | 3 |
| C12orf4 | RBBP6 | 0.728044 | 3 | 0 | 3 |
| C12orf4 | CSNK2A2 | 0.72751 | 3 | 0 | 3 |
| C12orf4 | TMEM237 | 0.724218 | 3 | 0 | 3 |
| C12orf4 | LMBRD2 | 0.715412 | 3 | 0 | 3 |
| C12orf4 | MRPL10 | 0.71533 | 3 | 0 | 3 |
| C12orf4 | SCNM1 | 0.704414 | 3 | 0 | 3 |
| C12orf4 | BACH1 | 0.704227 | 3 | 0 | 3 |
| C12orf4 | WDR11 | 0.697508 | 3 | 0 | 3 |
| C12orf4 | NCOR1 | 0.691265 | 4 | 0 | 3 |
| C12orf4 | RAPGEF6 | 0.687633 | 3 | 0 | 3 |
| C12orf4 | PTTG1IP | 0.684256 | 3 | 0 | 3 |
| C12orf4 | ZSCAN16 | 0.684026 | 3 | 0 | 3 |
| C12orf4 | ZNF140 | 0.683654 | 4 | 0 | 4 |
| C12orf4 | PSMG3 | 0.679572 | 3 | 0 | 3 |
| C12orf4 | LCOR | 0.679503 | 4 | 0 | 4 |
| C12orf4 | USP24 | 0.677569 | 4 | 0 | 3 |
| C12orf4 | PIGB | 0.677187 | 4 | 0 | 3 |
For details and further investigation, click here
