| Full name: pseudouridine synthase 10 | Alias Symbol: FLJ32312 | ||
| Type: protein-coding gene | Cytoband: 2p16.1-p15 | ||
| Entrez ID: 150962 | HGNC ID: HGNC:26505 | Ensembl Gene: ENSG00000162927 | OMIM ID: 612787 |
| Drug and gene relationship at DGIdb | |||
Expression of PUS10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PUS10 | 150962 | 229362_at | 0.5542 | 0.4709 | |
| GSE26886 | PUS10 | 150962 | 229362_at | -0.1421 | 0.4231 | |
| GSE45670 | PUS10 | 150962 | 229362_at | 0.3391 | 0.0646 | |
| GSE53622 | PUS10 | 150962 | 27288 | 0.3957 | 0.0002 | |
| GSE53624 | PUS10 | 150962 | 27288 | 0.3125 | 0.0000 | |
| GSE63941 | PUS10 | 150962 | 229362_at | -0.4810 | 0.2448 | |
| GSE77861 | PUS10 | 150962 | 1553280_at | -0.1290 | 0.4178 | |
| GSE97050 | PUS10 | 150962 | A_23_P412029 | 0.2636 | 0.3765 | |
| SRP007169 | PUS10 | 150962 | RNAseq | -0.1174 | 0.8018 | |
| SRP008496 | PUS10 | 150962 | RNAseq | 0.3517 | 0.3126 | |
| SRP064894 | PUS10 | 150962 | RNAseq | 0.3923 | 0.1290 | |
| SRP133303 | PUS10 | 150962 | RNAseq | 0.4951 | 0.0042 | |
| SRP159526 | PUS10 | 150962 | RNAseq | 0.0370 | 0.8898 | |
| SRP193095 | PUS10 | 150962 | RNAseq | -0.0020 | 0.9877 | |
| SRP219564 | PUS10 | 150962 | RNAseq | 1.1527 | 0.0657 | |
| TCGA | PUS10 | 150962 | RNAseq | 0.1970 | 0.0171 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PUS10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PUS10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PUS10 | 150962 | 12 | 0 | 18 | |
| GSE20123 | PUS10 | 150962 | 11 | 0 | 19 | |
| GSE43470 | PUS10 | 150962 | 7 | 0 | 36 | |
| GSE46452 | PUS10 | 150962 | 2 | 3 | 54 | |
| GSE47630 | PUS10 | 150962 | 8 | 0 | 32 | |
| GSE54993 | PUS10 | 150962 | 0 | 6 | 64 | |
| GSE54994 | PUS10 | 150962 | 12 | 0 | 41 | |
| GSE60625 | PUS10 | 150962 | 0 | 3 | 8 | |
| GSE74703 | PUS10 | 150962 | 7 | 0 | 29 | |
| GSE74704 | PUS10 | 150962 | 10 | 0 | 10 | |
| TCGA | PUS10 | 150962 | 36 | 3 | 57 |
Total number of gains: 105; Total number of losses: 15; Total Number of normals: 368.
Somatic mutations of PUS10:
Generating mutation plots.
Highly correlated genes for PUS10:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PUS10 | AGPAT3 | 0.808223 | 3 | 0 | 3 |
| PUS10 | SCAMP3 | 0.803555 | 3 | 0 | 3 |
| PUS10 | NR2F6 | 0.795445 | 3 | 0 | 3 |
| PUS10 | RABEP2 | 0.790732 | 3 | 0 | 3 |
| PUS10 | ZBTB44 | 0.782851 | 3 | 0 | 3 |
| PUS10 | RRP1B | 0.772045 | 3 | 0 | 3 |
| PUS10 | ZNF578 | 0.763755 | 3 | 0 | 3 |
| PUS10 | XPNPEP1 | 0.749603 | 3 | 0 | 3 |
| PUS10 | PLEKHM2 | 0.749294 | 3 | 0 | 3 |
| PUS10 | ADNP | 0.742319 | 3 | 0 | 3 |
| PUS10 | PCNT | 0.738343 | 3 | 0 | 3 |
| PUS10 | ABHD16A | 0.731898 | 4 | 0 | 4 |
| PUS10 | UHMK1 | 0.728764 | 3 | 0 | 3 |
| PUS10 | RUNDC1 | 0.721226 | 3 | 0 | 3 |
| PUS10 | MTCH2 | 0.717946 | 3 | 0 | 3 |
| PUS10 | CCDC15 | 0.713623 | 3 | 0 | 3 |
| PUS10 | ZNF879 | 0.708015 | 3 | 0 | 3 |
| PUS10 | RWDD2B | 0.705877 | 3 | 0 | 3 |
| PUS10 | C2CD2 | 0.701738 | 3 | 0 | 3 |
| PUS10 | SLC35B3 | 0.701736 | 5 | 0 | 4 |
For details and further investigation, click here
