| Full name: RWD domain containing 2B | Alias Symbol: GL011 | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 10069 | HGNC ID: HGNC:1302 | Ensembl Gene: ENSG00000156253 | OMIM ID: 617843 |
| Drug and gene relationship at DGIdb | |||
Expression of RWDD2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RWDD2B | 10069 | 218377_s_at | -0.3519 | 0.1729 | |
| GSE20347 | RWDD2B | 10069 | 218377_s_at | -0.3010 | 0.0015 | |
| GSE23400 | RWDD2B | 10069 | 218377_s_at | -0.0931 | 0.0298 | |
| GSE26886 | RWDD2B | 10069 | 218377_s_at | -0.5896 | 0.0003 | |
| GSE29001 | RWDD2B | 10069 | 218377_s_at | -0.0063 | 0.9856 | |
| GSE38129 | RWDD2B | 10069 | 218377_s_at | -0.3284 | 0.0151 | |
| GSE45670 | RWDD2B | 10069 | 218377_s_at | 0.0134 | 0.9331 | |
| GSE53622 | RWDD2B | 10069 | 57264 | -0.2614 | 0.0027 | |
| GSE53624 | RWDD2B | 10069 | 21723 | -0.5220 | 0.0000 | |
| GSE63941 | RWDD2B | 10069 | 218377_s_at | -0.1715 | 0.8492 | |
| GSE77861 | RWDD2B | 10069 | 218377_s_at | -0.3653 | 0.0830 | |
| GSE97050 | RWDD2B | 10069 | A_23_P91487 | -0.2123 | 0.4391 | |
| SRP007169 | RWDD2B | 10069 | RNAseq | -0.8118 | 0.0387 | |
| SRP008496 | RWDD2B | 10069 | RNAseq | -0.3229 | 0.2279 | |
| SRP064894 | RWDD2B | 10069 | RNAseq | 0.4886 | 0.0191 | |
| SRP133303 | RWDD2B | 10069 | RNAseq | -0.2178 | 0.2576 | |
| SRP159526 | RWDD2B | 10069 | RNAseq | -0.0743 | 0.7935 | |
| SRP193095 | RWDD2B | 10069 | RNAseq | -0.4740 | 0.0000 | |
| SRP219564 | RWDD2B | 10069 | RNAseq | -0.3347 | 0.3660 | |
| TCGA | RWDD2B | 10069 | RNAseq | -0.0095 | 0.8824 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RWDD2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RWDD2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RWDD2B | 10069 | 2 | 10 | 18 | |
| GSE20123 | RWDD2B | 10069 | 2 | 10 | 18 | |
| GSE43470 | RWDD2B | 10069 | 1 | 8 | 34 | |
| GSE46452 | RWDD2B | 10069 | 1 | 21 | 37 | |
| GSE47630 | RWDD2B | 10069 | 6 | 17 | 17 | |
| GSE54993 | RWDD2B | 10069 | 9 | 1 | 60 | |
| GSE54994 | RWDD2B | 10069 | 1 | 9 | 43 | |
| GSE60625 | RWDD2B | 10069 | 0 | 0 | 11 | |
| GSE74703 | RWDD2B | 10069 | 1 | 6 | 29 | |
| GSE74704 | RWDD2B | 10069 | 2 | 6 | 12 | |
| TCGA | RWDD2B | 10069 | 9 | 37 | 50 |
Total number of gains: 34; Total number of losses: 125; Total Number of normals: 329.
Somatic mutations of RWDD2B:
Generating mutation plots.
Highly correlated genes for RWDD2B:
Showing top 20/712 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RWDD2B | UBA3 | 0.837231 | 3 | 0 | 3 |
| RWDD2B | TRMT11 | 0.810528 | 3 | 0 | 3 |
| RWDD2B | USP47 | 0.782622 | 3 | 0 | 3 |
| RWDD2B | ZNF304 | 0.771556 | 3 | 0 | 3 |
| RWDD2B | UBE2J1 | 0.770775 | 3 | 0 | 3 |
| RWDD2B | SSBP1 | 0.766803 | 3 | 0 | 3 |
| RWDD2B | ZNF398 | 0.747082 | 3 | 0 | 3 |
| RWDD2B | CTDSPL | 0.732514 | 5 | 0 | 4 |
| RWDD2B | MAP2K1 | 0.727928 | 3 | 0 | 3 |
| RWDD2B | GLUD2 | 0.727204 | 3 | 0 | 3 |
| RWDD2B | SREK1IP1 | 0.727024 | 3 | 0 | 3 |
| RWDD2B | GCC2 | 0.722886 | 3 | 0 | 3 |
| RWDD2B | TMEM126A | 0.718236 | 3 | 0 | 3 |
| RWDD2B | KDM2B | 0.718127 | 3 | 0 | 3 |
| RWDD2B | NT5DC2 | 0.716461 | 3 | 0 | 3 |
| RWDD2B | RXRA | 0.716112 | 3 | 0 | 3 |
| RWDD2B | TRIM33 | 0.713594 | 4 | 0 | 3 |
| RWDD2B | RAP2C | 0.711067 | 4 | 0 | 4 |
| RWDD2B | GLUD1 | 0.708668 | 3 | 0 | 3 |
| RWDD2B | PUS10 | 0.705877 | 3 | 0 | 3 |
For details and further investigation, click here
