R3HDM2

 

Full name: R3H domain containing 2 Alias Symbol: KIAA1002
Type: protein-coding gene Cytoband: 12q13.3
Entrez ID: 22864 HGNC ID: HGNC:29167 Ensembl Gene: ENSG00000179912 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of R3HDM2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 R3HDM2 22864 203831_at -0.0666 0.8197
GSE20347 R3HDM2 22864 203831_at 0.0393 0.7119
GSE23400 R3HDM2 22864 203831_at 0.1530 0.0024
GSE26886 R3HDM2 22864 203831_at 0.2652 0.2843
GSE29001 R3HDM2 22864 203831_at 0.0336 0.9215
GSE38129 R3HDM2 22864 203831_at 0.0706 0.4188
GSE45670 R3HDM2 22864 203831_at -0.0253 0.8450
GSE53622 R3HDM2 22864 11199 0.0351 0.5443
GSE53624 R3HDM2 22864 24790 0.0279 0.6481
GSE63941 R3HDM2 22864 203831_at 0.5524 0.1697
GSE77861 R3HDM2 22864 203831_at 0.2267 0.1617
GSE97050 R3HDM2 22864 A_23_P10374 -0.1482 0.5499
SRP007169 R3HDM2 22864 RNAseq 0.6959 0.0810
SRP008496 R3HDM2 22864 RNAseq 0.7082 0.0029
SRP064894 R3HDM2 22864 RNAseq 0.1973 0.3448
SRP133303 R3HDM2 22864 RNAseq 0.2182 0.0870
SRP159526 R3HDM2 22864 RNAseq 0.0463 0.8881
SRP193095 R3HDM2 22864 RNAseq 0.2384 0.0538
SRP219564 R3HDM2 22864 RNAseq 0.2776 0.2714
TCGA R3HDM2 22864 RNAseq -0.0365 0.4120

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by R3HDM2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of R3HDM2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 R3HDM2 22864 7 1 22
GSE20123 R3HDM2 22864 7 0 23
GSE43470 R3HDM2 22864 2 0 41
GSE46452 R3HDM2 22864 8 1 50
GSE47630 R3HDM2 22864 10 2 28
GSE54993 R3HDM2 22864 0 5 65
GSE54994 R3HDM2 22864 4 1 48
GSE60625 R3HDM2 22864 0 0 11
GSE74703 R3HDM2 22864 2 0 34
GSE74704 R3HDM2 22864 4 0 16
TCGA R3HDM2 22864 14 10 72

Total number of gains: 58; Total number of losses: 20; Total Number of normals: 410.  

 

Somatic mutations of R3HDM2:

 

Generating mutation plots.

 

Highly correlated genes for R3HDM2:

 

Showing top 20/406 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
R3HDM2BCORL10.837561303
R3HDM2REC80.819304303
R3HDM2CLIP20.787969303
R3HDM2ORAI30.787765303
R3HDM2LSM14A0.785651303
R3HDM2SOCS70.781059303
R3HDM2ELP30.774861303
R3HDM2TRAF3IP10.76255303
R3HDM2ZNF760.758458303
R3HDM2MID1IP10.757623303
R3HDM2NRL0.75686303
R3HDM2POU2F10.751286303
R3HDM2FAM86C10.749091303
R3HDM2ZNF3580.747834403
R3HDM2DHX330.747496303
R3HDM2RICTOR0.745895303
R3HDM2PIP5K1C0.743601403
R3HDM2SH2B10.740902303
R3HDM2LGI20.737273303
R3HDM2SORBS30.736134404

For details and further investigation, click here