| Full name: RAB14, member RAS oncogene family | Alias Symbol: FBP|RAB-14 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 51552 | HGNC ID: HGNC:16524 | Ensembl Gene: ENSG00000119396 | OMIM ID: 612673 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
RAB14 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04152 | AMPK signaling pathway |
Expression of RAB14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB14 | 51552 | 211503_s_at | -0.4011 | 0.3311 | |
| GSE20347 | RAB14 | 51552 | 211503_s_at | -0.7774 | 0.0000 | |
| GSE23400 | RAB14 | 51552 | 200927_s_at | -0.1542 | 0.1135 | |
| GSE26886 | RAB14 | 51552 | 211503_s_at | -0.6041 | 0.0117 | |
| GSE29001 | RAB14 | 51552 | 211503_s_at | -0.5346 | 0.0465 | |
| GSE38129 | RAB14 | 51552 | 211503_s_at | -0.3327 | 0.1269 | |
| GSE45670 | RAB14 | 51552 | 200927_s_at | -0.2760 | 0.0777 | |
| GSE53622 | RAB14 | 51552 | 70433 | -0.8245 | 0.0000 | |
| GSE53624 | RAB14 | 51552 | 70433 | -0.7192 | 0.0000 | |
| GSE63941 | RAB14 | 51552 | 200927_s_at | 0.0254 | 0.9536 | |
| GSE77861 | RAB14 | 51552 | 211503_s_at | 0.1419 | 0.6572 | |
| GSE97050 | RAB14 | 51552 | A_24_P115511 | -0.3385 | 0.2000 | |
| SRP007169 | RAB14 | 51552 | RNAseq | -0.1767 | 0.6690 | |
| SRP008496 | RAB14 | 51552 | RNAseq | -0.2095 | 0.4113 | |
| SRP064894 | RAB14 | 51552 | RNAseq | -0.3206 | 0.0324 | |
| SRP133303 | RAB14 | 51552 | RNAseq | -0.2400 | 0.1072 | |
| SRP159526 | RAB14 | 51552 | RNAseq | -0.6444 | 0.0015 | |
| SRP193095 | RAB14 | 51552 | RNAseq | -0.6817 | 0.0000 | |
| SRP219564 | RAB14 | 51552 | RNAseq | -0.4619 | 0.1747 | |
| TCGA | RAB14 | 51552 | RNAseq | -0.0035 | 0.9377 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAB14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB14 | 51552 | 3 | 7 | 20 | |
| GSE20123 | RAB14 | 51552 | 3 | 7 | 20 | |
| GSE43470 | RAB14 | 51552 | 5 | 4 | 34 | |
| GSE46452 | RAB14 | 51552 | 6 | 13 | 40 | |
| GSE47630 | RAB14 | 51552 | 3 | 16 | 21 | |
| GSE54993 | RAB14 | 51552 | 3 | 3 | 64 | |
| GSE54994 | RAB14 | 51552 | 9 | 10 | 34 | |
| GSE60625 | RAB14 | 51552 | 0 | 0 | 11 | |
| GSE74703 | RAB14 | 51552 | 5 | 3 | 28 | |
| GSE74704 | RAB14 | 51552 | 2 | 5 | 13 | |
| TCGA | RAB14 | 51552 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 92; Total Number of normals: 330.
Somatic mutations of RAB14:
Generating mutation plots.
Highly correlated genes for RAB14:
Showing top 20/901 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB14 | GMPPB | 0.748539 | 3 | 0 | 3 |
| RAB14 | UNK | 0.724038 | 4 | 0 | 4 |
| RAB14 | NAA20 | 0.719442 | 3 | 0 | 3 |
| RAB14 | MTIF3 | 0.704702 | 5 | 0 | 5 |
| RAB14 | GPR108 | 0.703042 | 3 | 0 | 3 |
| RAB14 | CCDC12 | 0.696285 | 6 | 0 | 5 |
| RAB14 | ZBTB43 | 0.696007 | 10 | 0 | 10 |
| RAB14 | PCSK7 | 0.691945 | 3 | 0 | 3 |
| RAB14 | UBE2D2 | 0.690621 | 3 | 0 | 3 |
| RAB14 | NUFIP2 | 0.68992 | 3 | 0 | 3 |
| RAB14 | PRRG4 | 0.689455 | 5 | 0 | 4 |
| RAB14 | ZFAND6 | 0.688641 | 3 | 0 | 3 |
| RAB14 | NDUFA13 | 0.68782 | 4 | 0 | 3 |
| RAB14 | CCNYL1 | 0.681571 | 3 | 0 | 3 |
| RAB14 | SOWAHC | 0.680132 | 5 | 0 | 4 |
| RAB14 | TMEM19 | 0.678756 | 5 | 0 | 5 |
| RAB14 | SF3A1 | 0.676546 | 3 | 0 | 3 |
| RAB14 | SLC35D2 | 0.676352 | 5 | 0 | 4 |
| RAB14 | CCDC90B | 0.676167 | 5 | 0 | 5 |
| RAB14 | STX17 | 0.674811 | 9 | 0 | 8 |
For details and further investigation, click here
