| Full name: syntaxin 17 | Alias Symbol: FLJ20651 | ||
| Type: protein-coding gene | Cytoband: 9q31.1 | ||
| Entrez ID: 55014 | HGNC ID: HGNC:11432 | Ensembl Gene: ENSG00000136874 | OMIM ID: 604204 |
| Drug and gene relationship at DGIdb | |||
Expression of STX17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX17 | 55014 | 222708_s_at | -0.5233 | 0.0828 | |
| GSE20347 | STX17 | 55014 | 218666_s_at | -0.9455 | 0.0000 | |
| GSE23400 | STX17 | 55014 | 218666_s_at | -0.3280 | 0.0000 | |
| GSE26886 | STX17 | 55014 | 222708_s_at | -2.4309 | 0.0000 | |
| GSE29001 | STX17 | 55014 | 218666_s_at | -0.6313 | 0.0224 | |
| GSE38129 | STX17 | 55014 | 218666_s_at | -0.7550 | 0.0000 | |
| GSE45670 | STX17 | 55014 | 226662_at | -0.4204 | 0.0316 | |
| GSE53622 | STX17 | 55014 | 117028 | -0.6697 | 0.0000 | |
| GSE53624 | STX17 | 55014 | 117028 | -0.7591 | 0.0000 | |
| GSE63941 | STX17 | 55014 | 222708_s_at | 1.4390 | 0.0015 | |
| GSE77861 | STX17 | 55014 | 222708_s_at | -0.1795 | 0.4577 | |
| GSE97050 | STX17 | 55014 | A_33_P3269149 | -0.2377 | 0.3254 | |
| SRP007169 | STX17 | 55014 | RNAseq | -1.3898 | 0.0000 | |
| SRP008496 | STX17 | 55014 | RNAseq | -1.1697 | 0.0000 | |
| SRP064894 | STX17 | 55014 | RNAseq | -0.5905 | 0.0002 | |
| SRP133303 | STX17 | 55014 | RNAseq | -0.3527 | 0.0557 | |
| SRP159526 | STX17 | 55014 | RNAseq | -0.6846 | 0.0213 | |
| SRP193095 | STX17 | 55014 | RNAseq | -0.6374 | 0.0000 | |
| SRP219564 | STX17 | 55014 | RNAseq | -0.5257 | 0.0305 | |
| TCGA | STX17 | 55014 | RNAseq | -0.1371 | 0.0082 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by STX17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX17 | 55014 | 4 | 9 | 17 | |
| GSE20123 | STX17 | 55014 | 5 | 8 | 17 | |
| GSE43470 | STX17 | 55014 | 7 | 3 | 33 | |
| GSE46452 | STX17 | 55014 | 6 | 13 | 40 | |
| GSE47630 | STX17 | 55014 | 1 | 17 | 22 | |
| GSE54993 | STX17 | 55014 | 3 | 3 | 64 | |
| GSE54994 | STX17 | 55014 | 9 | 11 | 33 | |
| GSE60625 | STX17 | 55014 | 0 | 0 | 11 | |
| GSE74703 | STX17 | 55014 | 6 | 3 | 27 | |
| GSE74704 | STX17 | 55014 | 2 | 5 | 13 | |
| TCGA | STX17 | 55014 | 26 | 24 | 46 |
Total number of gains: 69; Total number of losses: 96; Total Number of normals: 323.
Somatic mutations of STX17:
Generating mutation plots.
Highly correlated genes for STX17:
Showing top 20/1157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX17 | PPM1B | 0.811213 | 3 | 0 | 3 |
| STX17 | NIPSNAP3A | 0.759394 | 6 | 0 | 6 |
| STX17 | TBRG1 | 0.754914 | 3 | 0 | 3 |
| STX17 | ALKBH8 | 0.748372 | 3 | 0 | 3 |
| STX17 | RMND5B | 0.743442 | 10 | 0 | 10 |
| STX17 | PAIP2 | 0.716487 | 3 | 0 | 3 |
| STX17 | GPD1L | 0.709528 | 10 | 0 | 10 |
| STX17 | AK2 | 0.708899 | 3 | 0 | 3 |
| STX17 | ZNF436 | 0.70822 | 3 | 0 | 3 |
| STX17 | PRSS3 | 0.708216 | 8 | 0 | 8 |
| STX17 | MGST2 | 0.708155 | 10 | 0 | 9 |
| STX17 | DCAF8 | 0.707331 | 4 | 0 | 4 |
| STX17 | CCDC6 | 0.704409 | 9 | 0 | 9 |
| STX17 | TOM1L1 | 0.704251 | 3 | 0 | 3 |
| STX17 | SH3GLB2 | 0.702803 | 10 | 0 | 9 |
| STX17 | UPK1A | 0.702184 | 10 | 0 | 10 |
| STX17 | RAB5A | 0.702174 | 10 | 0 | 10 |
| STX17 | KIAA0232 | 0.701255 | 10 | 0 | 9 |
| STX17 | GDPD3 | 0.700349 | 9 | 0 | 9 |
| STX17 | FAM120AOS | 0.699528 | 3 | 0 | 3 |
For details and further investigation, click here
