| Full name: nuclear FMR1 interacting protein 2 | Alias Symbol: KIAA1321|MGC117262|PIG1|182-FIP|FIP-82|82-FIP | ||
| Type: protein-coding gene | Cytoband: 17q11.1 | ||
| Entrez ID: 57532 | HGNC ID: HGNC:17634 | Ensembl Gene: ENSG00000108256 | OMIM ID: 609356 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUFIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUFIP2 | 57532 | 224939_at | 0.2860 | 0.2928 | |
| GSE26886 | NUFIP2 | 57532 | 224939_at | -0.9836 | 0.0000 | |
| GSE45670 | NUFIP2 | 57532 | 224939_at | 0.3122 | 0.1747 | |
| GSE53622 | NUFIP2 | 57532 | 83460 | -0.1077 | 0.0490 | |
| GSE53624 | NUFIP2 | 57532 | 83460 | -0.0375 | 0.5883 | |
| GSE63941 | NUFIP2 | 57532 | 224939_at | 0.0558 | 0.9075 | |
| GSE77861 | NUFIP2 | 57532 | 224939_at | 0.6896 | 0.1055 | |
| GSE97050 | NUFIP2 | 57532 | A_24_P791829 | -0.1577 | 0.5127 | |
| SRP007169 | NUFIP2 | 57532 | RNAseq | 0.7386 | 0.0340 | |
| SRP008496 | NUFIP2 | 57532 | RNAseq | 0.6260 | 0.0017 | |
| SRP064894 | NUFIP2 | 57532 | RNAseq | -0.1119 | 0.5969 | |
| SRP133303 | NUFIP2 | 57532 | RNAseq | 0.3785 | 0.0025 | |
| SRP159526 | NUFIP2 | 57532 | RNAseq | -0.1127 | 0.6134 | |
| SRP193095 | NUFIP2 | 57532 | RNAseq | 0.0720 | 0.3014 | |
| SRP219564 | NUFIP2 | 57532 | RNAseq | -0.2088 | 0.5540 | |
| TCGA | NUFIP2 | 57532 | RNAseq | -0.0451 | 0.2790 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUFIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUFIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUFIP2 | 57532 | 8 | 1 | 21 | |
| GSE20123 | NUFIP2 | 57532 | 9 | 1 | 20 | |
| GSE43470 | NUFIP2 | 57532 | 0 | 1 | 42 | |
| GSE46452 | NUFIP2 | 57532 | 33 | 1 | 25 | |
| GSE47630 | NUFIP2 | 57532 | 7 | 1 | 32 | |
| GSE54993 | NUFIP2 | 57532 | 2 | 3 | 65 | |
| GSE54994 | NUFIP2 | 57532 | 7 | 6 | 40 | |
| GSE60625 | NUFIP2 | 57532 | 4 | 0 | 7 | |
| GSE74703 | NUFIP2 | 57532 | 0 | 1 | 35 | |
| GSE74704 | NUFIP2 | 57532 | 6 | 1 | 13 | |
| TCGA | NUFIP2 | 57532 | 21 | 10 | 65 |
Total number of gains: 97; Total number of losses: 26; Total Number of normals: 365.
Somatic mutations of NUFIP2:
Generating mutation plots.
Highly correlated genes for NUFIP2:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUFIP2 | ZNF260 | 0.846584 | 3 | 0 | 3 |
| NUFIP2 | SBNO1 | 0.817222 | 3 | 0 | 3 |
| NUFIP2 | PKP4 | 0.812742 | 3 | 0 | 3 |
| NUFIP2 | DNAH14 | 0.803622 | 3 | 0 | 3 |
| NUFIP2 | ZNF451 | 0.800023 | 3 | 0 | 3 |
| NUFIP2 | MYNN | 0.787881 | 3 | 0 | 3 |
| NUFIP2 | USP45 | 0.787051 | 3 | 0 | 3 |
| NUFIP2 | SP1 | 0.783674 | 3 | 0 | 3 |
| NUFIP2 | ZBTB37 | 0.783201 | 3 | 0 | 3 |
| NUFIP2 | ORC2 | 0.779355 | 3 | 0 | 3 |
| NUFIP2 | CLK2 | 0.779074 | 3 | 0 | 3 |
| NUFIP2 | CTDSPL | 0.774319 | 3 | 0 | 3 |
| NUFIP2 | TBP | 0.773754 | 3 | 0 | 3 |
| NUFIP2 | CBFA2T2 | 0.77251 | 3 | 0 | 3 |
| NUFIP2 | TBK1 | 0.769835 | 3 | 0 | 3 |
| NUFIP2 | PTS | 0.758711 | 3 | 0 | 3 |
| NUFIP2 | WWP1 | 0.758557 | 4 | 0 | 4 |
| NUFIP2 | CWC25 | 0.756725 | 3 | 0 | 3 |
| NUFIP2 | CBX5 | 0.749898 | 3 | 0 | 3 |
| NUFIP2 | PRKX | 0.744552 | 3 | 0 | 3 |
For details and further investigation, click here
