| Full name: coiled-coil domain containing 90B | Alias Symbol: MDS025|MDS011 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 60492 | HGNC ID: HGNC:28108 | Ensembl Gene: ENSG00000137500 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCDC90B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC90B | 60492 | 218288_s_at | -0.5552 | 0.0426 | |
| GSE20347 | CCDC90B | 60492 | 218288_s_at | -0.6219 | 0.0009 | |
| GSE23400 | CCDC90B | 60492 | 218288_s_at | -0.1627 | 0.0291 | |
| GSE26886 | CCDC90B | 60492 | 218288_s_at | -0.4520 | 0.0221 | |
| GSE29001 | CCDC90B | 60492 | 218288_s_at | -0.8175 | 0.0060 | |
| GSE38129 | CCDC90B | 60492 | 218288_s_at | -0.4137 | 0.0028 | |
| GSE45670 | CCDC90B | 60492 | 218288_s_at | -0.1799 | 0.3856 | |
| GSE53622 | CCDC90B | 60492 | 97897 | -0.1611 | 0.0033 | |
| GSE53624 | CCDC90B | 60492 | 97897 | 0.0003 | 0.9965 | |
| GSE63941 | CCDC90B | 60492 | 218288_s_at | -0.6200 | 0.2505 | |
| GSE77861 | CCDC90B | 60492 | 218288_s_at | -0.6948 | 0.0735 | |
| GSE97050 | CCDC90B | 60492 | A_23_P162127 | -0.1019 | 0.7872 | |
| SRP007169 | CCDC90B | 60492 | RNAseq | -1.6390 | 0.0000 | |
| SRP008496 | CCDC90B | 60492 | RNAseq | -1.1008 | 0.0000 | |
| SRP064894 | CCDC90B | 60492 | RNAseq | -0.4283 | 0.0148 | |
| SRP133303 | CCDC90B | 60492 | RNAseq | -0.4141 | 0.0012 | |
| SRP159526 | CCDC90B | 60492 | RNAseq | -1.0293 | 0.0000 | |
| SRP193095 | CCDC90B | 60492 | RNAseq | -0.8857 | 0.0000 | |
| SRP219564 | CCDC90B | 60492 | RNAseq | -0.7043 | 0.0025 | |
| TCGA | CCDC90B | 60492 | RNAseq | -0.0247 | 0.7006 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CCDC90B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC90B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC90B | 60492 | 2 | 9 | 19 | |
| GSE20123 | CCDC90B | 60492 | 2 | 9 | 19 | |
| GSE43470 | CCDC90B | 60492 | 3 | 4 | 36 | |
| GSE46452 | CCDC90B | 60492 | 5 | 23 | 31 | |
| GSE47630 | CCDC90B | 60492 | 3 | 18 | 19 | |
| GSE54993 | CCDC90B | 60492 | 8 | 2 | 60 | |
| GSE54994 | CCDC90B | 60492 | 6 | 18 | 29 | |
| GSE60625 | CCDC90B | 60492 | 0 | 3 | 8 | |
| GSE74703 | CCDC90B | 60492 | 2 | 3 | 31 | |
| GSE74704 | CCDC90B | 60492 | 2 | 6 | 12 | |
| TCGA | CCDC90B | 60492 | 18 | 36 | 42 |
Total number of gains: 51; Total number of losses: 131; Total Number of normals: 306.
Somatic mutations of CCDC90B:
Generating mutation plots.
Highly correlated genes for CCDC90B:
Showing top 20/927 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC90B | FBXL3 | 0.751837 | 5 | 0 | 4 |
| CCDC90B | KCTD6 | 0.737252 | 4 | 0 | 3 |
| CCDC90B | METTL9 | 0.73708 | 6 | 0 | 6 |
| CCDC90B | MTPN | 0.736625 | 3 | 0 | 3 |
| CCDC90B | COMMD1 | 0.732607 | 3 | 0 | 3 |
| CCDC90B | EIF5B | 0.729194 | 3 | 0 | 3 |
| CCDC90B | KDM5D | 0.728784 | 3 | 0 | 3 |
| CCDC90B | BRWD1 | 0.714098 | 4 | 0 | 4 |
| CCDC90B | IREB2 | 0.712722 | 4 | 0 | 4 |
| CCDC90B | ZNF557 | 0.711684 | 3 | 0 | 3 |
| CCDC90B | FAM122A | 0.709102 | 3 | 0 | 3 |
| CCDC90B | NDUFS4 | 0.708279 | 6 | 0 | 6 |
| CCDC90B | C2orf16 | 0.707573 | 3 | 0 | 3 |
| CCDC90B | EPB41L5 | 0.70749 | 3 | 0 | 3 |
| CCDC90B | STXBP5 | 0.700698 | 6 | 0 | 6 |
| CCDC90B | NIPSNAP3A | 0.699941 | 5 | 0 | 4 |
| CCDC90B | FCHO2 | 0.698097 | 4 | 0 | 4 |
| CCDC90B | AZI2 | 0.696844 | 7 | 0 | 6 |
| CCDC90B | DENND4C | 0.693027 | 7 | 0 | 6 |
| CCDC90B | MRFAP1 | 0.691167 | 3 | 0 | 3 |
For details and further investigation, click here
