| Full name: N(alpha)-acetyltransferase 20, NatB catalytic subunit | Alias Symbol: dJ1002M8.1|NAT3 | ||
| Type: protein-coding gene | Cytoband: 20p11.23 | ||
| Entrez ID: 51126 | HGNC ID: HGNC:15908 | Ensembl Gene: ENSG00000173418 | OMIM ID: 610833 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NAA20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAA20 | 51126 | 223040_at | 0.0524 | 0.9567 | |
| GSE26886 | NAA20 | 51126 | 223040_at | -1.1006 | 0.0001 | |
| GSE45670 | NAA20 | 51126 | 223040_at | -0.1839 | 0.3233 | |
| GSE53622 | NAA20 | 51126 | 71534 | -0.4812 | 0.0001 | |
| GSE53624 | NAA20 | 51126 | 71534 | -0.6187 | 0.0000 | |
| GSE63941 | NAA20 | 51126 | 223040_at | 0.6656 | 0.0801 | |
| GSE77861 | NAA20 | 51126 | 223040_at | -0.4200 | 0.1071 | |
| GSE97050 | NAA20 | 51126 | A_23_P102770 | -0.0337 | 0.9469 | |
| SRP007169 | NAA20 | 51126 | RNAseq | -1.5867 | 0.0004 | |
| SRP008496 | NAA20 | 51126 | RNAseq | -1.3079 | 0.0000 | |
| SRP064894 | NAA20 | 51126 | RNAseq | -1.1376 | 0.0000 | |
| SRP133303 | NAA20 | 51126 | RNAseq | -0.6205 | 0.0002 | |
| SRP159526 | NAA20 | 51126 | RNAseq | -0.6356 | 0.1084 | |
| SRP193095 | NAA20 | 51126 | RNAseq | -1.0272 | 0.0000 | |
| SRP219564 | NAA20 | 51126 | RNAseq | -0.9371 | 0.0784 | |
| TCGA | NAA20 | 51126 | RNAseq | 0.2588 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by NAA20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAA20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAA20 | 51126 | 13 | 2 | 15 | |
| GSE20123 | NAA20 | 51126 | 13 | 2 | 15 | |
| GSE43470 | NAA20 | 51126 | 11 | 1 | 31 | |
| GSE46452 | NAA20 | 51126 | 27 | 1 | 31 | |
| GSE47630 | NAA20 | 51126 | 17 | 4 | 19 | |
| GSE54993 | NAA20 | 51126 | 0 | 15 | 55 | |
| GSE54994 | NAA20 | 51126 | 26 | 2 | 25 | |
| GSE60625 | NAA20 | 51126 | 0 | 0 | 11 | |
| GSE74703 | NAA20 | 51126 | 8 | 1 | 27 | |
| GSE74704 | NAA20 | 51126 | 7 | 2 | 11 | |
| TCGA | NAA20 | 51126 | 43 | 11 | 42 |
Total number of gains: 165; Total number of losses: 41; Total Number of normals: 282.
Somatic mutations of NAA20:
Generating mutation plots.
Highly correlated genes for NAA20:
Showing top 20/1037 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAA20 | ZNF217 | 0.86007 | 3 | 0 | 3 |
| NAA20 | EIF2B4 | 0.853171 | 3 | 0 | 3 |
| NAA20 | MCCC2 | 0.850095 | 3 | 0 | 3 |
| NAA20 | TMEM167A | 0.814981 | 3 | 0 | 3 |
| NAA20 | CARHSP1 | 0.777737 | 4 | 0 | 4 |
| NAA20 | ARFGAP2 | 0.767374 | 3 | 0 | 3 |
| NAA20 | ZFC3H1 | 0.765547 | 3 | 0 | 3 |
| NAA20 | ARPC1A | 0.764712 | 3 | 0 | 3 |
| NAA20 | LCMT1 | 0.761977 | 3 | 0 | 3 |
| NAA20 | MKRN2 | 0.758981 | 3 | 0 | 3 |
| NAA20 | TMED2 | 0.755263 | 3 | 0 | 3 |
| NAA20 | PKN2 | 0.755084 | 3 | 0 | 3 |
| NAA20 | APPL2 | 0.753848 | 3 | 0 | 3 |
| NAA20 | PRMT2 | 0.753518 | 3 | 0 | 3 |
| NAA20 | SH3PXD2A | 0.753448 | 3 | 0 | 3 |
| NAA20 | TRIP12 | 0.750073 | 3 | 0 | 3 |
| NAA20 | HDHD2 | 0.749705 | 4 | 0 | 4 |
| NAA20 | CIAPIN1 | 0.748231 | 4 | 0 | 3 |
| NAA20 | UGP2 | 0.746186 | 3 | 0 | 3 |
| NAA20 | ZCCHC8 | 0.745781 | 3 | 0 | 3 |
For details and further investigation, click here
