| Full name: proline rich and Gla domain 4 | Alias Symbol: TMG4 | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 79056 | HGNC ID: HGNC:30799 | Ensembl Gene: ENSG00000135378 | OMIM ID: 611690 |
| Drug and gene relationship at DGIdb | |||
Expression of PRRG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRRG4 | 79056 | 238513_at | -0.0642 | 0.9714 | |
| GSE20347 | PRRG4 | 79056 | 207291_at | -1.3125 | 0.0000 | |
| GSE23400 | PRRG4 | 79056 | 207291_at | -0.2520 | 0.0887 | |
| GSE26886 | PRRG4 | 79056 | 238513_at | -1.4468 | 0.0000 | |
| GSE29001 | PRRG4 | 79056 | 207291_at | -0.6148 | 0.2303 | |
| GSE38129 | PRRG4 | 79056 | 207291_at | -0.2834 | 0.5928 | |
| GSE45670 | PRRG4 | 79056 | 238513_at | 0.2175 | 0.3467 | |
| GSE53622 | PRRG4 | 79056 | 141994 | -0.1781 | 0.3587 | |
| GSE53624 | PRRG4 | 79056 | 141994 | -0.3905 | 0.0000 | |
| GSE63941 | PRRG4 | 79056 | 238513_at | 4.5639 | 0.0002 | |
| GSE77861 | PRRG4 | 79056 | 238513_at | -0.6727 | 0.3166 | |
| GSE97050 | PRRG4 | 79056 | A_23_P127663 | 0.2258 | 0.5647 | |
| SRP007169 | PRRG4 | 79056 | RNAseq | -0.6725 | 0.1558 | |
| SRP008496 | PRRG4 | 79056 | RNAseq | -0.8430 | 0.0016 | |
| SRP064894 | PRRG4 | 79056 | RNAseq | -0.8507 | 0.0068 | |
| SRP133303 | PRRG4 | 79056 | RNAseq | 0.1435 | 0.5460 | |
| SRP159526 | PRRG4 | 79056 | RNAseq | -1.1276 | 0.0089 | |
| SRP193095 | PRRG4 | 79056 | RNAseq | -0.7905 | 0.0014 | |
| SRP219564 | PRRG4 | 79056 | RNAseq | -0.9667 | 0.1807 | |
| TCGA | PRRG4 | 79056 | RNAseq | 0.6205 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by PRRG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRRG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRRG4 | 79056 | 1 | 8 | 21 | |
| GSE20123 | PRRG4 | 79056 | 1 | 7 | 22 | |
| GSE43470 | PRRG4 | 79056 | 2 | 4 | 37 | |
| GSE46452 | PRRG4 | 79056 | 8 | 5 | 46 | |
| GSE47630 | PRRG4 | 79056 | 3 | 10 | 27 | |
| GSE54993 | PRRG4 | 79056 | 3 | 0 | 67 | |
| GSE54994 | PRRG4 | 79056 | 3 | 10 | 40 | |
| GSE60625 | PRRG4 | 79056 | 0 | 0 | 11 | |
| GSE74703 | PRRG4 | 79056 | 2 | 2 | 32 | |
| GSE74704 | PRRG4 | 79056 | 0 | 6 | 14 | |
| TCGA | PRRG4 | 79056 | 13 | 24 | 59 |
Total number of gains: 36; Total number of losses: 76; Total Number of normals: 376.
Somatic mutations of PRRG4:
Generating mutation plots.
Highly correlated genes for PRRG4:
Showing top 20/891 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRRG4 | MPZL2 | 0.761476 | 11 | 0 | 11 |
| PRRG4 | CERS3 | 0.75897 | 7 | 0 | 6 |
| PRRG4 | FAM83C | 0.737523 | 5 | 0 | 4 |
| PRRG4 | ZNF750 | 0.727351 | 10 | 0 | 10 |
| PRRG4 | RAPGEFL1 | 0.72441 | 11 | 0 | 11 |
| PRRG4 | STAP2 | 0.719062 | 8 | 0 | 8 |
| PRRG4 | DGKA | 0.718864 | 10 | 0 | 10 |
| PRRG4 | MPZL3 | 0.718542 | 7 | 0 | 7 |
| PRRG4 | MREG | 0.716308 | 12 | 0 | 11 |
| PRRG4 | DMKN | 0.716041 | 7 | 0 | 7 |
| PRRG4 | ZNF57 | 0.715534 | 4 | 0 | 4 |
| PRRG4 | JUP | 0.712015 | 11 | 0 | 9 |
| PRRG4 | TRIM29 | 0.711721 | 11 | 0 | 9 |
| PRRG4 | TGM1 | 0.711304 | 10 | 0 | 10 |
| PRRG4 | CDS1 | 0.708487 | 11 | 0 | 10 |
| PRRG4 | SLC9A3R1 | 0.704698 | 11 | 0 | 10 |
| PRRG4 | NIPAL1 | 0.704267 | 4 | 0 | 3 |
| PRRG4 | ARHGAP27 | 0.700375 | 7 | 0 | 7 |
| PRRG4 | STARD10 | 0.699929 | 3 | 0 | 3 |
| PRRG4 | SPAG16 | 0.697744 | 4 | 0 | 4 |
For details and further investigation, click here
