| Full name: RAB30, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 27314 | HGNC ID: HGNC:9770 | Ensembl Gene: ENSG00000137502 | OMIM ID: 605693 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB30 | 27314 | 228390_at | -0.2767 | 0.7740 | |
| GSE20347 | RAB30 | 27314 | 206530_at | -0.0562 | 0.5249 | |
| GSE23400 | RAB30 | 27314 | 206530_at | -0.1243 | 0.0008 | |
| GSE26886 | RAB30 | 27314 | 228390_at | 0.2270 | 0.6642 | |
| GSE29001 | RAB30 | 27314 | 206530_at | -0.1201 | 0.3304 | |
| GSE38129 | RAB30 | 27314 | 206530_at | -0.0906 | 0.1748 | |
| GSE45670 | RAB30 | 27314 | 229072_at | -0.6884 | 0.0099 | |
| GSE53622 | RAB30 | 27314 | 102285 | -0.0576 | 0.6096 | |
| GSE53624 | RAB30 | 27314 | 102285 | 0.0708 | 0.5037 | |
| GSE63941 | RAB30 | 27314 | 228390_at | -1.9985 | 0.0148 | |
| GSE77861 | RAB30 | 27314 | 228003_at | 0.1494 | 0.3839 | |
| GSE97050 | RAB30 | 27314 | A_24_P167338 | 0.1750 | 0.5551 | |
| SRP007169 | RAB30 | 27314 | RNAseq | 1.0069 | 0.0969 | |
| SRP008496 | RAB30 | 27314 | RNAseq | 0.9270 | 0.0057 | |
| SRP064894 | RAB30 | 27314 | RNAseq | -0.0312 | 0.9056 | |
| SRP133303 | RAB30 | 27314 | RNAseq | -0.1702 | 0.2981 | |
| SRP159526 | RAB30 | 27314 | RNAseq | -0.3436 | 0.4211 | |
| SRP193095 | RAB30 | 27314 | RNAseq | -0.0923 | 0.6335 | |
| SRP219564 | RAB30 | 27314 | RNAseq | -0.2955 | 0.4837 | |
| TCGA | RAB30 | 27314 | RNAseq | -0.0645 | 0.6266 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RAB30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB30 | 27314 | 2 | 9 | 19 | |
| GSE20123 | RAB30 | 27314 | 2 | 9 | 19 | |
| GSE43470 | RAB30 | 27314 | 3 | 4 | 36 | |
| GSE46452 | RAB30 | 27314 | 5 | 23 | 31 | |
| GSE47630 | RAB30 | 27314 | 3 | 18 | 19 | |
| GSE54993 | RAB30 | 27314 | 8 | 2 | 60 | |
| GSE54994 | RAB30 | 27314 | 6 | 18 | 29 | |
| GSE60625 | RAB30 | 27314 | 0 | 3 | 8 | |
| GSE74703 | RAB30 | 27314 | 2 | 3 | 31 | |
| GSE74704 | RAB30 | 27314 | 2 | 6 | 12 | |
| TCGA | RAB30 | 27314 | 18 | 36 | 42 |
Total number of gains: 51; Total number of losses: 131; Total Number of normals: 306.
Somatic mutations of RAB30:
Generating mutation plots.
Highly correlated genes for RAB30:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB30 | GNA12 | 0.745854 | 3 | 0 | 3 |
| RAB30 | RNASEH2C | 0.745349 | 3 | 0 | 3 |
| RAB30 | GYG2 | 0.726487 | 3 | 0 | 3 |
| RAB30 | FAM76B | 0.723484 | 4 | 0 | 4 |
| RAB30 | PLEKHM3 | 0.705217 | 3 | 0 | 3 |
| RAB30 | ZXDA | 0.687521 | 3 | 0 | 3 |
| RAB30 | ARHGAP9 | 0.681249 | 3 | 0 | 3 |
| RAB30 | CAPN3 | 0.678943 | 3 | 0 | 3 |
| RAB30 | TMSB15B | 0.673018 | 3 | 0 | 3 |
| RAB30 | KCNK2 | 0.666871 | 4 | 0 | 4 |
| RAB30 | USP32 | 0.665478 | 3 | 0 | 3 |
| RAB30 | FAM168A | 0.661809 | 3 | 0 | 3 |
| RAB30 | DSEL | 0.661487 | 3 | 0 | 3 |
| RAB30 | VKORC1 | 0.658064 | 3 | 0 | 3 |
| RAB30 | SKA2 | 0.656916 | 3 | 0 | 3 |
| RAB30 | CHST3 | 0.655994 | 4 | 0 | 4 |
| RAB30 | ZNF18 | 0.654448 | 3 | 0 | 3 |
| RAB30 | MCOLN3 | 0.647905 | 4 | 0 | 3 |
| RAB30 | TGFBR1 | 0.642657 | 4 | 0 | 3 |
| RAB30 | GALNT11 | 0.642366 | 3 | 0 | 3 |
For details and further investigation, click here
