| Full name: ubiquitin specific peptidase 32 | Alias Symbol: NY-REN-60|USP10 | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 84669 | HGNC ID: HGNC:19143 | Ensembl Gene: ENSG00000170832 | OMIM ID: 607740 |
| Drug and gene relationship at DGIdb | |||
Expression of USP32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP32 | 84669 | 226505_x_at | -0.1968 | 0.7541 | |
| GSE20347 | USP32 | 84669 | 211702_s_at | -0.1705 | 0.1341 | |
| GSE23400 | USP32 | 84669 | 211702_s_at | -0.0632 | 0.1246 | |
| GSE26886 | USP32 | 84669 | 226505_x_at | 0.6411 | 0.0080 | |
| GSE29001 | USP32 | 84669 | 211702_s_at | -0.2917 | 0.2415 | |
| GSE38129 | USP32 | 84669 | 211702_s_at | -0.0063 | 0.9575 | |
| GSE45670 | USP32 | 84669 | 226505_x_at | 0.0498 | 0.8210 | |
| GSE53622 | USP32 | 84669 | 127763 | 0.0293 | 0.6714 | |
| GSE53624 | USP32 | 84669 | 127763 | -0.0606 | 0.3317 | |
| GSE63941 | USP32 | 84669 | 226505_x_at | -1.0317 | 0.0153 | |
| GSE77861 | USP32 | 84669 | 226505_x_at | 0.4765 | 0.1370 | |
| GSE97050 | USP32 | 84669 | A_33_P3414362 | 0.3831 | 0.2477 | |
| SRP007169 | USP32 | 84669 | RNAseq | 1.2204 | 0.0021 | |
| SRP008496 | USP32 | 84669 | RNAseq | 0.9887 | 0.0002 | |
| SRP064894 | USP32 | 84669 | RNAseq | -0.1287 | 0.5670 | |
| SRP133303 | USP32 | 84669 | RNAseq | 0.2842 | 0.0680 | |
| SRP159526 | USP32 | 84669 | RNAseq | 0.0680 | 0.8157 | |
| SRP193095 | USP32 | 84669 | RNAseq | 0.0822 | 0.3628 | |
| SRP219564 | USP32 | 84669 | RNAseq | -0.4864 | 0.1119 | |
| TCGA | USP32 | 84669 | RNAseq | 0.0752 | 0.1282 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by USP32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP32 | 84669 | 5 | 1 | 24 | |
| GSE20123 | USP32 | 84669 | 5 | 1 | 24 | |
| GSE43470 | USP32 | 84669 | 5 | 0 | 38 | |
| GSE46452 | USP32 | 84669 | 32 | 0 | 27 | |
| GSE47630 | USP32 | 84669 | 7 | 1 | 32 | |
| GSE54993 | USP32 | 84669 | 2 | 5 | 63 | |
| GSE54994 | USP32 | 84669 | 9 | 5 | 39 | |
| GSE60625 | USP32 | 84669 | 4 | 0 | 7 | |
| GSE74703 | USP32 | 84669 | 5 | 0 | 31 | |
| GSE74704 | USP32 | 84669 | 4 | 1 | 15 | |
| TCGA | USP32 | 84669 | 29 | 6 | 61 |
Total number of gains: 107; Total number of losses: 20; Total Number of normals: 361.
Somatic mutations of USP32:
Generating mutation plots.
Highly correlated genes for USP32:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP32 | RBKS | 0.802517 | 3 | 0 | 3 |
| USP32 | ZMYM2 | 0.793776 | 3 | 0 | 3 |
| USP32 | DHRS7 | 0.793763 | 3 | 0 | 3 |
| USP32 | RB1 | 0.773944 | 3 | 0 | 3 |
| USP32 | STAU2 | 0.767724 | 3 | 0 | 3 |
| USP32 | PFDN1 | 0.767374 | 3 | 0 | 3 |
| USP32 | AP4E1 | 0.765467 | 3 | 0 | 3 |
| USP32 | USP40 | 0.764924 | 3 | 0 | 3 |
| USP32 | PPM1D | 0.762232 | 3 | 0 | 3 |
| USP32 | ZMPSTE24 | 0.759402 | 3 | 0 | 3 |
| USP32 | VPS37A | 0.757602 | 3 | 0 | 3 |
| USP32 | MIS12 | 0.756998 | 3 | 0 | 3 |
| USP32 | CNRIP1 | 0.747678 | 3 | 0 | 3 |
| USP32 | LYSMD3 | 0.742633 | 3 | 0 | 3 |
| USP32 | MITD1 | 0.738422 | 3 | 0 | 3 |
| USP32 | NEDD1 | 0.737929 | 3 | 0 | 3 |
| USP32 | KLHL7 | 0.733974 | 3 | 0 | 3 |
| USP32 | MYO1E | 0.732045 | 4 | 0 | 3 |
| USP32 | SGTB | 0.730289 | 4 | 0 | 4 |
| USP32 | PRRX1 | 0.726477 | 3 | 0 | 3 |
For details and further investigation, click here
