| Full name: Nedd4 family interacting protein 2 | Alias Symbol: KIAA1165|N4wbp5a | ||
| Type: protein-coding gene | Cytoband: 13q31.1 | ||
| Entrez ID: 54602 | HGNC ID: HGNC:18537 | Ensembl Gene: ENSG00000102471 | OMIM ID: 610041 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDFIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDFIP2 | 54602 | 224802_at | -0.3211 | 0.7185 | |
| GSE26886 | NDFIP2 | 54602 | 224802_at | -0.9510 | 0.0008 | |
| GSE45670 | NDFIP2 | 54602 | 224802_at | -0.0761 | 0.8076 | |
| GSE53622 | NDFIP2 | 54602 | 89968 | -0.4108 | 0.0022 | |
| GSE53624 | NDFIP2 | 54602 | 89968 | -0.7396 | 0.0000 | |
| GSE63941 | NDFIP2 | 54602 | 224802_at | 0.0888 | 0.8887 | |
| GSE77861 | NDFIP2 | 54602 | 224799_at | -1.4423 | 0.0008 | |
| GSE97050 | NDFIP2 | 54602 | A_24_P264909 | 0.0174 | 0.9891 | |
| SRP007169 | NDFIP2 | 54602 | RNAseq | -2.3723 | 0.0000 | |
| SRP008496 | NDFIP2 | 54602 | RNAseq | -1.8899 | 0.0000 | |
| SRP064894 | NDFIP2 | 54602 | RNAseq | -1.4974 | 0.0000 | |
| SRP133303 | NDFIP2 | 54602 | RNAseq | -0.0929 | 0.7682 | |
| SRP159526 | NDFIP2 | 54602 | RNAseq | -1.6996 | 0.0014 | |
| SRP193095 | NDFIP2 | 54602 | RNAseq | -1.2321 | 0.0000 | |
| SRP219564 | NDFIP2 | 54602 | RNAseq | -1.4788 | 0.0575 | |
| TCGA | NDFIP2 | 54602 | RNAseq | 0.0183 | 0.7908 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by NDFIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDFIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDFIP2 | 54602 | 3 | 11 | 16 | |
| GSE20123 | NDFIP2 | 54602 | 3 | 10 | 17 | |
| GSE43470 | NDFIP2 | 54602 | 3 | 11 | 29 | |
| GSE46452 | NDFIP2 | 54602 | 0 | 32 | 27 | |
| GSE47630 | NDFIP2 | 54602 | 3 | 27 | 10 | |
| GSE54993 | NDFIP2 | 54602 | 11 | 3 | 56 | |
| GSE54994 | NDFIP2 | 54602 | 3 | 14 | 36 | |
| GSE60625 | NDFIP2 | 54602 | 0 | 3 | 8 | |
| GSE74703 | NDFIP2 | 54602 | 2 | 9 | 25 | |
| GSE74704 | NDFIP2 | 54602 | 1 | 9 | 10 | |
| TCGA | NDFIP2 | 54602 | 11 | 34 | 51 |
Total number of gains: 40; Total number of losses: 163; Total Number of normals: 285.
Somatic mutations of NDFIP2:
Generating mutation plots.
Highly correlated genes for NDFIP2:
Showing top 20/1158 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDFIP2 | MBNL3 | 0.759562 | 3 | 0 | 3 |
| NDFIP2 | PAIP2B | 0.755614 | 3 | 0 | 3 |
| NDFIP2 | ZCCHC10 | 0.749734 | 4 | 0 | 4 |
| NDFIP2 | TRAPPC13 | 0.742983 | 3 | 0 | 3 |
| NDFIP2 | PRKAB1 | 0.738507 | 3 | 0 | 3 |
| NDFIP2 | HPSE | 0.737808 | 5 | 0 | 5 |
| NDFIP2 | PPIP5K2 | 0.735832 | 4 | 0 | 4 |
| NDFIP2 | SLC30A9 | 0.734039 | 4 | 0 | 4 |
| NDFIP2 | STRN | 0.730351 | 5 | 0 | 5 |
| NDFIP2 | GALE | 0.726164 | 5 | 0 | 5 |
| NDFIP2 | KIF21A | 0.726014 | 4 | 0 | 4 |
| NDFIP2 | CUL4B | 0.725765 | 3 | 0 | 3 |
| NDFIP2 | PDIK1L | 0.725037 | 3 | 0 | 3 |
| NDFIP2 | SLC31A1 | 0.724828 | 3 | 0 | 3 |
| NDFIP2 | PRRC1 | 0.724544 | 4 | 0 | 4 |
| NDFIP2 | SLCO2B1 | 0.720273 | 3 | 0 | 3 |
| NDFIP2 | ALG13 | 0.719711 | 3 | 0 | 3 |
| NDFIP2 | FRMD4B | 0.719366 | 7 | 0 | 6 |
| NDFIP2 | C3orf38 | 0.716487 | 5 | 0 | 5 |
| NDFIP2 | FAM174A | 0.7162 | 5 | 0 | 4 |
For details and further investigation, click here
