| Full name: ubiquitin conjugating enzyme E2 F (putative) | Alias Symbol: NCE2 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 140739 | HGNC ID: HGNC:12480 | Ensembl Gene: ENSG00000184182 | OMIM ID: 617700 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2F | 140739 | 225787_at | 0.2582 | 0.8496 | |
| GSE26886 | UBE2F | 140739 | 225783_at | -1.1313 | 0.0000 | |
| GSE45670 | UBE2F | 140739 | 225783_at | 0.2750 | 0.1126 | |
| GSE53622 | UBE2F | 140739 | 137434 | -0.2900 | 0.0000 | |
| GSE53624 | UBE2F | 140739 | 137434 | -0.5956 | 0.0000 | |
| GSE63941 | UBE2F | 140739 | 225787_at | -0.2173 | 0.5965 | |
| GSE77861 | UBE2F | 140739 | 225787_at | -0.6771 | 0.0077 | |
| GSE97050 | UBE2F | 140739 | A_23_P39561 | -0.1847 | 0.4229 | |
| SRP007169 | UBE2F | 140739 | RNAseq | -1.5660 | 0.0001 | |
| SRP008496 | UBE2F | 140739 | RNAseq | -1.3939 | 0.0000 | |
| SRP064894 | UBE2F | 140739 | RNAseq | -0.3069 | 0.1780 | |
| SRP133303 | UBE2F | 140739 | RNAseq | 0.0537 | 0.6619 | |
| SRP159526 | UBE2F | 140739 | RNAseq | -0.4841 | 0.0350 | |
| SRP193095 | UBE2F | 140739 | RNAseq | -0.7146 | 0.0000 | |
| SRP219564 | UBE2F | 140739 | RNAseq | -0.3699 | 0.2051 | |
| TCGA | UBE2F | 140739 | RNAseq | 0.0201 | 0.7216 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by UBE2F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2F | 140739 | 1 | 12 | 17 | |
| GSE20123 | UBE2F | 140739 | 1 | 12 | 17 | |
| GSE43470 | UBE2F | 140739 | 1 | 9 | 33 | |
| GSE46452 | UBE2F | 140739 | 0 | 5 | 54 | |
| GSE47630 | UBE2F | 140739 | 4 | 5 | 31 | |
| GSE54993 | UBE2F | 140739 | 3 | 2 | 65 | |
| GSE54994 | UBE2F | 140739 | 8 | 10 | 35 | |
| GSE60625 | UBE2F | 140739 | 0 | 3 | 8 | |
| GSE74703 | UBE2F | 140739 | 1 | 7 | 28 | |
| GSE74704 | UBE2F | 140739 | 1 | 5 | 14 | |
| TCGA | UBE2F | 140739 | 12 | 27 | 57 |
Total number of gains: 32; Total number of losses: 97; Total Number of normals: 359.
Somatic mutations of UBE2F:
Generating mutation plots.
Highly correlated genes for UBE2F:
Showing top 20/865 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2F | GLTP | 0.82587 | 3 | 0 | 3 |
| UBE2F | EXOC6B | 0.778841 | 3 | 0 | 3 |
| UBE2F | PRDM1 | 0.778478 | 3 | 0 | 3 |
| UBE2F | HEMK1 | 0.771434 | 3 | 0 | 3 |
| UBE2F | CRYBG3 | 0.766808 | 3 | 0 | 3 |
| UBE2F | ZDHHC21 | 0.756007 | 3 | 0 | 3 |
| UBE2F | SPAG16 | 0.746109 | 4 | 0 | 4 |
| UBE2F | PCBP1-AS1 | 0.744518 | 3 | 0 | 3 |
| UBE2F | KLB | 0.741032 | 3 | 0 | 3 |
| UBE2F | TPRG1 | 0.736612 | 4 | 0 | 4 |
| UBE2F | PSG5 | 0.734857 | 3 | 0 | 3 |
| UBE2F | NAGK | 0.732719 | 5 | 0 | 4 |
| UBE2F | C5orf66-AS1 | 0.730745 | 3 | 0 | 3 |
| UBE2F | FBXO3 | 0.729703 | 4 | 0 | 4 |
| UBE2F | KLK11 | 0.729437 | 3 | 0 | 3 |
| UBE2F | PLK3 | 0.72789 | 3 | 0 | 3 |
| UBE2F | CTTNBP2NL | 0.727886 | 5 | 0 | 5 |
| UBE2F | TM7SF2 | 0.727564 | 4 | 0 | 4 |
| UBE2F | ATP10B | 0.727041 | 3 | 0 | 3 |
| UBE2F | PPP1R7 | 0.725073 | 6 | 0 | 5 |
For details and further investigation, click here
