| Full name: NOP56 ribonucleoprotein | Alias Symbol: SCA36 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 10528 | HGNC ID: HGNC:15911 | Ensembl Gene: ENSG00000101361 | OMIM ID: 614154 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NOP56:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | NOP56 | 10528 | 71387 | 0.8241 | 0.0000 | |
| GSE53624 | NOP56 | 10528 | 71387 | 0.8492 | 0.0000 | |
| GSE97050 | NOP56 | A_19_P00801634 | 0.6219 | 0.1675 | ||
| SRP007169 | NOP56 | 10528 | RNAseq | 0.2590 | 0.5544 | |
| SRP008496 | NOP56 | 10528 | RNAseq | 0.3967 | 0.1579 | |
| SRP064894 | NOP56 | 10528 | RNAseq | 0.8987 | 0.0000 | |
| SRP133303 | NOP56 | 10528 | RNAseq | 0.6853 | 0.0000 | |
| SRP159526 | NOP56 | 10528 | RNAseq | 1.0532 | 0.0045 | |
| SRP193095 | NOP56 | 10528 | RNAseq | 0.5209 | 0.0000 | |
| SRP219564 | NOP56 | 10528 | RNAseq | 0.7417 | 0.0760 | |
| TCGA | NOP56 | 10528 | RNAseq | 0.2478 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NOP56 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOP56:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOP56 | 10528 | 12 | 4 | 14 | |
| GSE20123 | NOP56 | 10528 | 13 | 4 | 13 | |
| GSE43470 | NOP56 | 10528 | 10 | 1 | 32 | |
| GSE46452 | NOP56 | 10528 | 26 | 1 | 32 | |
| GSE47630 | NOP56 | 10528 | 18 | 4 | 18 | |
| GSE54993 | NOP56 | 10528 | 2 | 14 | 54 | |
| GSE54994 | NOP56 | 10528 | 24 | 2 | 27 | |
| GSE60625 | NOP56 | 10528 | 0 | 0 | 11 | |
| GSE74703 | NOP56 | 10528 | 9 | 1 | 26 | |
| GSE74704 | NOP56 | 10528 | 8 | 1 | 11 | |
| TCGA | NOP56 | 10528 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 43; Total Number of normals: 283.
Somatic mutations of NOP56:
Generating mutation plots.
Highly correlated genes for NOP56:
Showing top 20/786 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOP56 | DCAF13 | 0.807602 | 3 | 0 | 3 |
| NOP56 | BRIX1 | 0.791429 | 3 | 0 | 3 |
| NOP56 | WDHD1 | 0.783309 | 3 | 0 | 3 |
| NOP56 | PRKDC | 0.782628 | 3 | 0 | 3 |
| NOP56 | SNRPB | 0.777516 | 3 | 0 | 3 |
| NOP56 | MMP12 | 0.777056 | 3 | 0 | 3 |
| NOP56 | GINS1 | 0.775877 | 3 | 0 | 3 |
| NOP56 | LAPTM4B | 0.768669 | 3 | 0 | 3 |
| NOP56 | ATRN | 0.768396 | 3 | 0 | 3 |
| NOP56 | ATAD2 | 0.768013 | 3 | 0 | 3 |
| NOP56 | CDCA3 | 0.766932 | 3 | 0 | 3 |
| NOP56 | TPX2 | 0.766147 | 3 | 0 | 3 |
| NOP56 | NXT1 | 0.764535 | 3 | 0 | 3 |
| NOP56 | PCNA | 0.762556 | 3 | 0 | 3 |
| NOP56 | SLC3A2 | 0.761528 | 3 | 0 | 3 |
| NOP56 | CDKN3 | 0.757555 | 3 | 0 | 3 |
| NOP56 | ILF2 | 0.757052 | 3 | 0 | 3 |
| NOP56 | MTBP | 0.755642 | 3 | 0 | 3 |
| NOP56 | MFAP2 | 0.755556 | 3 | 0 | 3 |
| NOP56 | NDC80 | 0.75434 | 3 | 0 | 3 |
For details and further investigation, click here
