| Full name: coenzyme Q2, polyprenyltransferase | Alias Symbol: CL640|FLJ26072 | ||
| Type: protein-coding gene | Cytoband: 4q21.23 | ||
| Entrez ID: 27235 | HGNC ID: HGNC:25223 | Ensembl Gene: ENSG00000173085 | OMIM ID: 609825 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COQ2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COQ2 | 27235 | 213379_at | 0.0953 | 0.9135 | |
| GSE20347 | COQ2 | 27235 | 213379_at | -0.3940 | 0.0084 | |
| GSE23400 | COQ2 | 27235 | 213379_at | 0.0016 | 0.9872 | |
| GSE26886 | COQ2 | 27235 | 213379_at | -0.3707 | 0.1626 | |
| GSE29001 | COQ2 | 27235 | 213379_at | -0.4576 | 0.1408 | |
| GSE38129 | COQ2 | 27235 | 213379_at | -0.0446 | 0.8465 | |
| GSE45670 | COQ2 | 27235 | 213379_at | -0.2621 | 0.0338 | |
| GSE53622 | COQ2 | 27235 | 6768 | -0.0392 | 0.6806 | |
| GSE53624 | COQ2 | 27235 | 6768 | -0.0617 | 0.3516 | |
| GSE63941 | COQ2 | 27235 | 213379_at | -0.2097 | 0.6715 | |
| GSE77861 | COQ2 | 27235 | 213379_at | -0.8002 | 0.0510 | |
| GSE97050 | COQ2 | 27235 | A_23_P124733 | 0.3544 | 0.2504 | |
| SRP007169 | COQ2 | 27235 | RNAseq | -0.5657 | 0.1662 | |
| SRP008496 | COQ2 | 27235 | RNAseq | -0.5076 | 0.1213 | |
| SRP064894 | COQ2 | 27235 | RNAseq | 0.0215 | 0.9005 | |
| SRP133303 | COQ2 | 27235 | RNAseq | 0.2174 | 0.2321 | |
| SRP159526 | COQ2 | 27235 | RNAseq | -0.6930 | 0.0126 | |
| SRP193095 | COQ2 | 27235 | RNAseq | -0.5365 | 0.0003 | |
| SRP219564 | COQ2 | 27235 | RNAseq | -0.1178 | 0.7088 | |
| TCGA | COQ2 | 27235 | RNAseq | 0.1991 | 0.0042 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COQ2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COQ2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COQ2 | 27235 | 2 | 11 | 17 | |
| GSE20123 | COQ2 | 27235 | 2 | 11 | 17 | |
| GSE43470 | COQ2 | 27235 | 0 | 13 | 30 | |
| GSE46452 | COQ2 | 27235 | 1 | 36 | 22 | |
| GSE47630 | COQ2 | 27235 | 0 | 20 | 20 | |
| GSE54993 | COQ2 | 27235 | 8 | 0 | 62 | |
| GSE54994 | COQ2 | 27235 | 1 | 9 | 43 | |
| GSE60625 | COQ2 | 27235 | 0 | 0 | 11 | |
| GSE74703 | COQ2 | 27235 | 0 | 11 | 25 | |
| GSE74704 | COQ2 | 27235 | 1 | 6 | 13 | |
| TCGA | COQ2 | 27235 | 11 | 34 | 51 |
Total number of gains: 26; Total number of losses: 151; Total Number of normals: 311.
Somatic mutations of COQ2:
Generating mutation plots.
Highly correlated genes for COQ2:
Showing top 20/390 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COQ2 | AP1S3 | 0.7289 | 3 | 0 | 3 |
| COQ2 | DSP | 0.704748 | 4 | 0 | 4 |
| COQ2 | MORN2 | 0.691469 | 3 | 0 | 3 |
| COQ2 | GSTP1 | 0.655821 | 4 | 0 | 4 |
| COQ2 | POM121 | 0.650235 | 3 | 0 | 3 |
| COQ2 | SSU72 | 0.647833 | 3 | 0 | 3 |
| COQ2 | SH3PXD2A-AS1 | 0.645555 | 3 | 0 | 3 |
| COQ2 | CDC23 | 0.645348 | 3 | 0 | 3 |
| COQ2 | RAD51B | 0.643002 | 3 | 0 | 3 |
| COQ2 | CEP76 | 0.641424 | 5 | 0 | 4 |
| COQ2 | ZDHHC12 | 0.639046 | 3 | 0 | 3 |
| COQ2 | SLC50A1 | 0.633173 | 3 | 0 | 3 |
| COQ2 | SNRNP200 | 0.632295 | 3 | 0 | 3 |
| COQ2 | ADH7 | 0.630341 | 5 | 0 | 5 |
| COQ2 | GPR87 | 0.628232 | 5 | 0 | 3 |
| COQ2 | LPIN1 | 0.62721 | 3 | 0 | 3 |
| COQ2 | CNKSR1 | 0.626644 | 5 | 0 | 4 |
| COQ2 | GRHL3 | 0.62308 | 4 | 0 | 3 |
| COQ2 | MAL2 | 0.622857 | 4 | 0 | 3 |
| COQ2 | ALG14 | 0.622161 | 4 | 0 | 4 |
For details and further investigation, click here
