| Full name: chromosome 5 open reading frame 30 | Alias Symbol: FLJ25291 | ||
| Type: protein-coding gene | Cytoband: 5q21.1 | ||
| Entrez ID: 90355 | HGNC ID: HGNC:25052 | Ensembl Gene: ENSG00000181751 | OMIM ID: 616608 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of C5orf30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C5orf30 | 90355 | 221823_at | 0.5528 | 0.1364 | |
| GSE20347 | C5orf30 | 90355 | 221823_at | 0.0701 | 0.7091 | |
| GSE23400 | C5orf30 | 90355 | 221823_at | 0.1542 | 0.0015 | |
| GSE26886 | C5orf30 | 90355 | 221823_at | -0.4845 | 0.1429 | |
| GSE29001 | C5orf30 | 90355 | 221823_at | 0.2542 | 0.3979 | |
| GSE38129 | C5orf30 | 90355 | 221823_at | 0.0604 | 0.6686 | |
| GSE45670 | C5orf30 | 90355 | 221823_at | -0.1835 | 0.3288 | |
| GSE53622 | C5orf30 | 90355 | 370 | -0.2507 | 0.0325 | |
| GSE53624 | C5orf30 | 90355 | 370 | 0.1197 | 0.1874 | |
| GSE63941 | C5orf30 | 90355 | 221823_at | -0.7348 | 0.3630 | |
| GSE77861 | C5orf30 | 90355 | 221823_at | 0.0031 | 0.9903 | |
| GSE97050 | C5orf30 | 90355 | A_23_P122007 | 0.1043 | 0.6544 | |
| SRP007169 | C5orf30 | 90355 | RNAseq | -0.2186 | 0.6762 | |
| SRP008496 | C5orf30 | 90355 | RNAseq | -0.1910 | 0.6027 | |
| SRP064894 | C5orf30 | 90355 | RNAseq | -0.0231 | 0.9056 | |
| SRP133303 | C5orf30 | 90355 | RNAseq | 0.4548 | 0.0555 | |
| SRP159526 | C5orf30 | 90355 | RNAseq | 0.4900 | 0.0681 | |
| SRP193095 | C5orf30 | 90355 | RNAseq | -0.9028 | 0.0004 | |
| SRP219564 | C5orf30 | 90355 | RNAseq | -0.0439 | 0.9435 | |
| TCGA | C5orf30 | 90355 | RNAseq | -0.4204 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C5orf30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C5orf30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C5orf30 | 90355 | 1 | 13 | 16 | |
| GSE20123 | C5orf30 | 90355 | 1 | 13 | 16 | |
| GSE43470 | C5orf30 | 90355 | 3 | 9 | 31 | |
| GSE46452 | C5orf30 | 90355 | 0 | 28 | 31 | |
| GSE47630 | C5orf30 | 90355 | 0 | 20 | 20 | |
| GSE54993 | C5orf30 | 90355 | 9 | 1 | 60 | |
| GSE54994 | C5orf30 | 90355 | 1 | 17 | 35 | |
| GSE60625 | C5orf30 | 90355 | 0 | 0 | 11 | |
| GSE74703 | C5orf30 | 90355 | 2 | 7 | 27 | |
| GSE74704 | C5orf30 | 90355 | 1 | 7 | 12 | |
| TCGA | C5orf30 | 90355 | 2 | 44 | 50 |
Total number of gains: 20; Total number of losses: 159; Total Number of normals: 309.
Somatic mutations of C5orf30:
Generating mutation plots.
Highly correlated genes for C5orf30:
Showing top 20/29 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C5orf30 | LCORL | 0.688782 | 3 | 0 | 3 |
| C5orf30 | SMG7 | 0.682743 | 3 | 0 | 3 |
| C5orf30 | TIGD7 | 0.654629 | 3 | 0 | 3 |
| C5orf30 | CCDC81 | 0.644223 | 3 | 0 | 3 |
| C5orf30 | MDC1 | 0.616839 | 3 | 0 | 3 |
| C5orf30 | RANBP2 | 0.615214 | 5 | 0 | 4 |
| C5orf30 | ARFGEF1 | 0.610903 | 4 | 0 | 3 |
| C5orf30 | NRIP3 | 0.609915 | 4 | 0 | 3 |
| C5orf30 | PRPF3 | 0.598453 | 5 | 0 | 3 |
| C5orf30 | ZNF519 | 0.59643 | 3 | 0 | 3 |
| C5orf30 | AKAP1 | 0.584446 | 3 | 0 | 3 |
| C5orf30 | GRK4 | 0.57974 | 4 | 0 | 3 |
| C5orf30 | ZBTB24 | 0.575687 | 5 | 0 | 3 |
| C5orf30 | ZNF30 | 0.562864 | 5 | 0 | 3 |
| C5orf30 | RPL7 | 0.560054 | 5 | 0 | 4 |
| C5orf30 | POP1 | 0.558263 | 4 | 0 | 3 |
| C5orf30 | CCNT2 | 0.558043 | 4 | 0 | 3 |
| C5orf30 | GLDC | 0.554233 | 5 | 0 | 3 |
| C5orf30 | CBX3 | 0.549181 | 4 | 0 | 3 |
| C5orf30 | MPC2 | 0.542574 | 4 | 0 | 3 |
For details and further investigation, click here
