| Full name: ring finger protein, transmembrane 1 | Alias Symbol: PTD016 | ||
| Type: protein-coding gene | Cytoband: 17q23.1 | ||
| Entrez ID: 51136 | HGNC ID: HGNC:30206 | Ensembl Gene: ENSG00000189050 | OMIM ID: 615172 |
| Drug and gene relationship at DGIdb | |||
Expression of RNFT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNFT1 | 51136 | 227268_at | -0.2156 | 0.8077 | |
| GSE20347 | RNFT1 | 51136 | 221195_at | -0.0260 | 0.6670 | |
| GSE23400 | RNFT1 | 51136 | 221195_at | 0.0462 | 0.0136 | |
| GSE26886 | RNFT1 | 51136 | 227268_at | -0.2018 | 0.5940 | |
| GSE29001 | RNFT1 | 51136 | 221195_at | 0.0702 | 0.5185 | |
| GSE38129 | RNFT1 | 51136 | 221195_at | 0.0648 | 0.2279 | |
| GSE45670 | RNFT1 | 51136 | 227268_at | 0.2356 | 0.1464 | |
| GSE53622 | RNFT1 | 51136 | 12034 | 0.1803 | 0.0668 | |
| GSE53624 | RNFT1 | 51136 | 12034 | -0.1851 | 0.0510 | |
| GSE63941 | RNFT1 | 51136 | 227268_at | -0.2885 | 0.6091 | |
| GSE77861 | RNFT1 | 51136 | 227268_at | -0.5010 | 0.1220 | |
| GSE97050 | RNFT1 | 51136 | A_23_P207299 | 0.4672 | 0.1450 | |
| SRP007169 | RNFT1 | 51136 | RNAseq | -0.1712 | 0.6552 | |
| SRP008496 | RNFT1 | 51136 | RNAseq | -0.0172 | 0.9526 | |
| SRP064894 | RNFT1 | 51136 | RNAseq | 0.3102 | 0.2417 | |
| SRP133303 | RNFT1 | 51136 | RNAseq | 0.2917 | 0.0309 | |
| SRP159526 | RNFT1 | 51136 | RNAseq | 0.0280 | 0.8932 | |
| SRP193095 | RNFT1 | 51136 | RNAseq | -0.3730 | 0.0004 | |
| SRP219564 | RNFT1 | 51136 | RNAseq | 0.0588 | 0.8693 | |
| TCGA | RNFT1 | 51136 | RNAseq | 0.0713 | 0.2844 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNFT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNFT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNFT1 | 51136 | 5 | 1 | 24 | |
| GSE20123 | RNFT1 | 51136 | 5 | 1 | 24 | |
| GSE43470 | RNFT1 | 51136 | 5 | 0 | 38 | |
| GSE46452 | RNFT1 | 51136 | 32 | 0 | 27 | |
| GSE47630 | RNFT1 | 51136 | 7 | 1 | 32 | |
| GSE54993 | RNFT1 | 51136 | 2 | 5 | 63 | |
| GSE54994 | RNFT1 | 51136 | 9 | 5 | 39 | |
| GSE60625 | RNFT1 | 51136 | 4 | 0 | 7 | |
| GSE74703 | RNFT1 | 51136 | 5 | 0 | 31 | |
| GSE74704 | RNFT1 | 51136 | 4 | 1 | 15 | |
| TCGA | RNFT1 | 51136 | 28 | 7 | 61 |
Total number of gains: 106; Total number of losses: 21; Total Number of normals: 361.
Somatic mutations of RNFT1:
Generating mutation plots.
Highly correlated genes for RNFT1:
Showing top 20/296 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNFT1 | NPAS2 | 0.836834 | 3 | 0 | 3 |
| RNFT1 | ELK3 | 0.827157 | 3 | 0 | 3 |
| RNFT1 | RREB1 | 0.826232 | 3 | 0 | 3 |
| RNFT1 | IPMK | 0.821426 | 3 | 0 | 3 |
| RNFT1 | NHSL1 | 0.807659 | 3 | 0 | 3 |
| RNFT1 | STX3 | 0.807023 | 3 | 0 | 3 |
| RNFT1 | MPZL3 | 0.769178 | 3 | 0 | 3 |
| RNFT1 | MAP2K4 | 0.7611 | 3 | 0 | 3 |
| RNFT1 | GAPVD1 | 0.758763 | 3 | 0 | 3 |
| RNFT1 | FRMD6 | 0.757143 | 3 | 0 | 3 |
| RNFT1 | ATMIN | 0.751618 | 3 | 0 | 3 |
| RNFT1 | RBAK | 0.741194 | 3 | 0 | 3 |
| RNFT1 | ULK3 | 0.740618 | 3 | 0 | 3 |
| RNFT1 | CHIC2 | 0.738307 | 3 | 0 | 3 |
| RNFT1 | STRN | 0.737525 | 4 | 0 | 3 |
| RNFT1 | LYRM7 | 0.736908 | 3 | 0 | 3 |
| RNFT1 | EAF1 | 0.732744 | 3 | 0 | 3 |
| RNFT1 | ZNF770 | 0.728622 | 3 | 0 | 3 |
| RNFT1 | ZNF101 | 0.72796 | 3 | 0 | 3 |
| RNFT1 | C18orf25 | 0.724608 | 3 | 0 | 3 |
For details and further investigation, click here
