PAPOLG

 

Full name: poly(A) polymerase gamma Alias Symbol: FLJ12972
Type: protein-coding gene Cytoband: 2p16.1
Entrez ID: 64895 HGNC ID: HGNC:14982 Ensembl Gene: ENSG00000115421 OMIM ID: 616865
Drug and gene relationship at DGIdb

 

Expression of PAPOLG:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PAPOLG 64895 222839_s_at 0.7151 0.1351
GSE20347 PAPOLG 64895 222273_at 0.0921 0.7082
GSE23400 PAPOLG 64895 222273_at 0.3018 0.0076
GSE26886 PAPOLG 64895 222839_s_at 0.5567 0.0163
GSE29001 PAPOLG 64895 222273_at 0.2793 0.5367
GSE38129 PAPOLG 64895 222273_at 0.1614 0.3607
GSE45670 PAPOLG 64895 222839_s_at 0.5777 0.0004
GSE53622 PAPOLG 64895 55289 0.3841 0.0000
GSE53624 PAPOLG 64895 55289 0.5472 0.0000
GSE63941 PAPOLG 64895 222839_s_at -0.0124 0.9815
GSE77861 PAPOLG 64895 222839_s_at 0.9134 0.0060
GSE97050 PAPOLG 64895 A_23_P209694 0.3418 0.2583
SRP007169 PAPOLG 64895 RNAseq 0.8757 0.0230
SRP008496 PAPOLG 64895 RNAseq 0.8169 0.0003
SRP064894 PAPOLG 64895 RNAseq 0.3281 0.1143
SRP133303 PAPOLG 64895 RNAseq 0.8323 0.0050
SRP159526 PAPOLG 64895 RNAseq 0.5831 0.0000
SRP193095 PAPOLG 64895 RNAseq 0.3076 0.0021
SRP219564 PAPOLG 64895 RNAseq 0.5453 0.1524
TCGA PAPOLG 64895 RNAseq 0.1788 0.0011

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PAPOLG expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PAPOLG:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PAPOLG 64895 11 0 19
GSE20123 PAPOLG 64895 10 0 20
GSE43470 PAPOLG 64895 7 0 36
GSE46452 PAPOLG 64895 2 3 54
GSE47630 PAPOLG 64895 8 0 32
GSE54993 PAPOLG 64895 0 6 64
GSE54994 PAPOLG 64895 12 0 41
GSE60625 PAPOLG 64895 0 3 8
GSE74703 PAPOLG 64895 7 0 29
GSE74704 PAPOLG 64895 10 0 10
TCGA PAPOLG 64895 36 2 58

Total number of gains: 103; Total number of losses: 14; Total Number of normals: 371.  

 

Somatic mutations of PAPOLG:

 

Generating mutation plots.

 

Highly correlated genes for PAPOLG:

 

Showing top 20/1271 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PAPOLGGCDH0.805917303
PAPOLGISY10.804587303
PAPOLGTMC70.797217303
PAPOLGHAS30.770797303
PAPOLGMED260.763509303
PAPOLGSLC35B30.753145303
PAPOLGU2SURP0.751668505
PAPOLGNAA250.747554303
PAPOLGSENP10.736414403
PAPOLGMOGS0.73504505
PAPOLGZXDA0.731719303
PAPOLGSPNS10.728787403
PAPOLGBUB10.728094605
PAPOLGASXL10.725062303
PAPOLGRBBP50.722741504
PAPOLGZNF4840.719897505
PAPOLGCDCA30.717441606
PAPOLGC12orf730.716643404
PAPOLGZNF1410.714393303
PAPOLGCHCHD30.71341303

For details and further investigation, click here