TMEM138

 

Full name: transmembrane protein 138 Alias Symbol: HSPC196|JBTS16
Type: protein-coding gene Cytoband: 11q12.2
Entrez ID: 51524 HGNC ID: HGNC:26944 Ensembl Gene: ENSG00000149483 OMIM ID: 614459
Drug and gene relationship at DGIdb

 

Expression of TMEM138:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM138 51524 223113_at 0.7285 0.0104
GSE26886 TMEM138 51524 223113_at 0.6805 0.0148
GSE45670 TMEM138 51524 223113_at 0.7958 0.0000
GSE53622 TMEM138 51524 34945 1.0696 0.0000
GSE53624 TMEM138 51524 34945 1.0872 0.0000
GSE63941 TMEM138 51524 223113_at 0.5947 0.2354
GSE77861 TMEM138 51524 223113_at 0.9872 0.0011
GSE97050 TMEM138 51524 A_23_P24723 0.6241 0.1198
SRP007169 TMEM138 51524 RNAseq 1.0158 0.0037
SRP008496 TMEM138 51524 RNAseq 0.9075 0.0001
SRP064894 TMEM138 51524 RNAseq 0.8677 0.0000
SRP133303 TMEM138 51524 RNAseq 0.5857 0.0019
SRP159526 TMEM138 51524 RNAseq 1.0634 0.0000
SRP193095 TMEM138 51524 RNAseq 0.5095 0.0000
SRP219564 TMEM138 51524 RNAseq 0.8876 0.0049
TCGA TMEM138 51524 RNAseq 0.2336 0.0000

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by TMEM138 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM138:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM138 51524 4 5 21
GSE20123 TMEM138 51524 4 5 21
GSE43470 TMEM138 51524 2 6 35
GSE46452 TMEM138 51524 8 4 47
GSE47630 TMEM138 51524 3 8 29
GSE54993 TMEM138 51524 3 0 67
GSE54994 TMEM138 51524 5 5 43
GSE60625 TMEM138 51524 0 3 8
GSE74703 TMEM138 51524 2 3 31
GSE74704 TMEM138 51524 3 3 14
TCGA TMEM138 51524 15 10 71

Total number of gains: 49; Total number of losses: 52; Total Number of normals: 387.  

 

Somatic mutations of TMEM138:

 

Generating mutation plots.

 

Highly correlated genes for TMEM138:

 

Showing top 20/2122 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM138BORA0.805575404
TMEM138CIAO10.804514303
TMEM138CDCA20.797667404
TMEM138CISD20.790853303
TMEM138C1orf1310.781632707
TMEM138TFRC0.780242606
TMEM138CKAP50.779592707
TMEM138PDIA40.77801606
TMEM138ECT20.776543505
TMEM138RNMT0.77487303
TMEM138LRP80.77475303
TMEM138FZD60.77283504
TMEM138LMNB20.772549505
TMEM138ARPC1B0.772158706
TMEM138MTBP0.770777505
TMEM138MRPS280.768509303
TMEM138CAD0.767449707
TMEM138MINPP10.767447606
TMEM138ATRN0.765963707
TMEM138HEATR10.764301707

For details and further investigation, click here