| Full name: EF-hand domain containing 1 | Alias Symbol: FLJ10466 | ||
| Type: protein-coding gene | Cytoband: 6p12.2 | ||
| Entrez ID: 114327 | HGNC ID: HGNC:16406 | Ensembl Gene: ENSG00000096093 | OMIM ID: 608815 |
| Drug and gene relationship at DGIdb | |||
Expression of EFHC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFHC1 | 114327 | 225656_at | -0.1440 | 0.7737 | |
| GSE20347 | EFHC1 | 114327 | 219833_s_at | 0.2254 | 0.2674 | |
| GSE23400 | EFHC1 | 114327 | 219833_s_at | 0.1883 | 0.0468 | |
| GSE26886 | EFHC1 | 114327 | 219833_s_at | 0.5334 | 0.0585 | |
| GSE29001 | EFHC1 | 114327 | 219833_s_at | -0.4565 | 0.1497 | |
| GSE38129 | EFHC1 | 114327 | 219833_s_at | 0.3252 | 0.0936 | |
| GSE45670 | EFHC1 | 114327 | 225656_at | -0.1294 | 0.5622 | |
| GSE53622 | EFHC1 | 114327 | 3341 | 0.1977 | 0.1466 | |
| GSE53624 | EFHC1 | 114327 | 3341 | 0.0050 | 0.9723 | |
| GSE63941 | EFHC1 | 114327 | 219833_s_at | -0.2198 | 0.7943 | |
| GSE77861 | EFHC1 | 114327 | 225656_at | 0.6928 | 0.4475 | |
| GSE97050 | EFHC1 | 114327 | A_32_P86245 | -0.1207 | 0.6310 | |
| SRP007169 | EFHC1 | 114327 | RNAseq | 0.3342 | 0.3918 | |
| SRP008496 | EFHC1 | 114327 | RNAseq | 0.4953 | 0.0960 | |
| SRP064894 | EFHC1 | 114327 | RNAseq | -0.0121 | 0.9309 | |
| SRP133303 | EFHC1 | 114327 | RNAseq | -0.0152 | 0.8849 | |
| SRP159526 | EFHC1 | 114327 | RNAseq | 0.2171 | 0.5419 | |
| SRP193095 | EFHC1 | 114327 | RNAseq | 0.0958 | 0.2784 | |
| SRP219564 | EFHC1 | 114327 | RNAseq | -0.1001 | 0.7270 | |
| TCGA | EFHC1 | 114327 | RNAseq | -0.1320 | 0.0974 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EFHC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFHC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFHC1 | 114327 | 7 | 2 | 21 | |
| GSE20123 | EFHC1 | 114327 | 7 | 2 | 21 | |
| GSE43470 | EFHC1 | 114327 | 5 | 0 | 38 | |
| GSE46452 | EFHC1 | 114327 | 2 | 10 | 47 | |
| GSE47630 | EFHC1 | 114327 | 7 | 5 | 28 | |
| GSE54993 | EFHC1 | 114327 | 3 | 1 | 66 | |
| GSE54994 | EFHC1 | 114327 | 8 | 4 | 41 | |
| GSE60625 | EFHC1 | 114327 | 0 | 3 | 8 | |
| GSE74703 | EFHC1 | 114327 | 5 | 0 | 31 | |
| GSE74704 | EFHC1 | 114327 | 3 | 1 | 16 | |
| TCGA | EFHC1 | 114327 | 21 | 13 | 62 |
Total number of gains: 68; Total number of losses: 41; Total Number of normals: 379.
Somatic mutations of EFHC1:
Generating mutation plots.
Highly correlated genes for EFHC1:
Showing top 20/182 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFHC1 | AGPAT5 | 0.748809 | 3 | 0 | 3 |
| EFHC1 | PKN2 | 0.743566 | 3 | 0 | 3 |
| EFHC1 | IAH1 | 0.72524 | 3 | 0 | 3 |
| EFHC1 | DOCK7 | 0.718386 | 3 | 0 | 3 |
| EFHC1 | SENP6 | 0.713357 | 4 | 0 | 4 |
| EFHC1 | WDR35 | 0.711031 | 4 | 0 | 3 |
| EFHC1 | VPS33A | 0.71069 | 3 | 0 | 3 |
| EFHC1 | ANAPC4 | 0.710607 | 3 | 0 | 3 |
| EFHC1 | CWF19L2 | 0.709844 | 3 | 0 | 3 |
| EFHC1 | C8orf76 | 0.704039 | 3 | 0 | 3 |
| EFHC1 | ZBTB34 | 0.700378 | 3 | 0 | 3 |
| EFHC1 | LCA5 | 0.696789 | 3 | 0 | 3 |
| EFHC1 | UTP23 | 0.69606 | 3 | 0 | 3 |
| EFHC1 | FBXW7 | 0.689027 | 3 | 0 | 3 |
| EFHC1 | DAP | 0.68669 | 3 | 0 | 3 |
| EFHC1 | RBM6 | 0.682475 | 3 | 0 | 3 |
| EFHC1 | NSMCE2 | 0.681313 | 3 | 0 | 3 |
| EFHC1 | PPP1R12A | 0.679243 | 3 | 0 | 3 |
| EFHC1 | MAGI1 | 0.678772 | 3 | 0 | 3 |
| EFHC1 | VEZT | 0.677243 | 4 | 0 | 3 |
For details and further investigation, click here
