| Full name: RNA binding motif protein 5 | Alias Symbol: LUCA15|LUCA-15|H37 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 10181 | HGNC ID: HGNC:9902 | Ensembl Gene: ENSG00000003756 | OMIM ID: 606884 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM5 | 10181 | 201395_at | -0.2427 | 0.5024 | |
| GSE20347 | RBM5 | 10181 | 201395_at | -0.3315 | 0.0281 | |
| GSE23400 | RBM5 | 10181 | 201395_at | -0.2183 | 0.0000 | |
| GSE26886 | RBM5 | 10181 | 201395_at | -0.9850 | 0.0000 | |
| GSE29001 | RBM5 | 10181 | 201395_at | -0.2297 | 0.4534 | |
| GSE38129 | RBM5 | 10181 | 201395_at | -0.4574 | 0.0000 | |
| GSE45670 | RBM5 | 10181 | 201395_at | -0.0539 | 0.6767 | |
| GSE53622 | RBM5 | 10181 | 38678 | -0.4205 | 0.0000 | |
| GSE53624 | RBM5 | 10181 | 57499 | -0.4904 | 0.0000 | |
| GSE63941 | RBM5 | 10181 | 201395_at | -0.4917 | 0.1265 | |
| GSE77861 | RBM5 | 10181 | 201395_at | -0.2488 | 0.1564 | |
| GSE97050 | RBM5 | 10181 | A_23_P18276 | -0.3971 | 0.1475 | |
| SRP007169 | RBM5 | 10181 | RNAseq | -0.3656 | 0.4287 | |
| SRP008496 | RBM5 | 10181 | RNAseq | -0.6257 | 0.0226 | |
| SRP064894 | RBM5 | 10181 | RNAseq | -0.4104 | 0.0062 | |
| SRP133303 | RBM5 | 10181 | RNAseq | -0.5492 | 0.0000 | |
| SRP159526 | RBM5 | 10181 | RNAseq | -0.7010 | 0.0003 | |
| SRP193095 | RBM5 | 10181 | RNAseq | -0.5642 | 0.0000 | |
| SRP219564 | RBM5 | 10181 | RNAseq | -0.5139 | 0.1664 | |
| TCGA | RBM5 | 10181 | RNAseq | -0.3069 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM5 | 10181 | 0 | 18 | 12 | |
| GSE20123 | RBM5 | 10181 | 0 | 19 | 11 | |
| GSE43470 | RBM5 | 10181 | 0 | 18 | 25 | |
| GSE46452 | RBM5 | 10181 | 2 | 16 | 41 | |
| GSE47630 | RBM5 | 10181 | 1 | 24 | 15 | |
| GSE54993 | RBM5 | 10181 | 6 | 2 | 62 | |
| GSE54994 | RBM5 | 10181 | 0 | 34 | 19 | |
| GSE60625 | RBM5 | 10181 | 5 | 0 | 6 | |
| GSE74703 | RBM5 | 10181 | 0 | 14 | 22 | |
| GSE74704 | RBM5 | 10181 | 0 | 12 | 8 | |
| TCGA | RBM5 | 10181 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 234; Total Number of normals: 240.
Somatic mutations of RBM5:
Generating mutation plots.
Highly correlated genes for RBM5:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM5 | ALKBH8 | 0.784184 | 3 | 0 | 3 |
| RBM5 | ZNF155 | 0.779939 | 3 | 0 | 3 |
| RBM5 | C6orf62 | 0.775277 | 3 | 0 | 3 |
| RBM5 | SUCLG1 | 0.772274 | 3 | 0 | 3 |
| RBM5 | YTHDF2 | 0.75688 | 3 | 0 | 3 |
| RBM5 | RBM4B | 0.753935 | 3 | 0 | 3 |
| RBM5 | HDHD2 | 0.739569 | 3 | 0 | 3 |
| RBM5 | KCTD15 | 0.736584 | 3 | 0 | 3 |
| RBM5 | MRPS18C | 0.734722 | 3 | 0 | 3 |
| RBM5 | ABHD14B | 0.726984 | 4 | 0 | 4 |
| RBM5 | PPP4R1 | 0.72666 | 3 | 0 | 3 |
| RBM5 | RRAGA | 0.724902 | 4 | 0 | 4 |
| RBM5 | APH1A | 0.717461 | 3 | 0 | 3 |
| RBM5 | MAMDC4 | 0.714035 | 3 | 0 | 3 |
| RBM5 | NUDCD3 | 0.712815 | 4 | 0 | 3 |
| RBM5 | ACTB | 0.712713 | 3 | 0 | 3 |
| RBM5 | TOPORS | 0.71074 | 4 | 0 | 3 |
| RBM5 | AP3M1 | 0.709965 | 3 | 0 | 3 |
| RBM5 | AP3D1 | 0.709195 | 3 | 0 | 3 |
| RBM5 | LEPROT | 0.7078 | 4 | 0 | 3 |
For details and further investigation, click here
