| Full name: zinc finger and BTB domain containing 4 | Alias Symbol: KIAA1538|KAISO-L1|ZNF903 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 57659 | HGNC ID: HGNC:23847 | Ensembl Gene: ENSG00000174282 | OMIM ID: 612308 |
| Drug and gene relationship at DGIdb | |||
Expression of ZBTB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB4 | 57659 | 225629_s_at | -0.1868 | 0.7789 | |
| GSE26886 | ZBTB4 | 57659 | 225629_s_at | 0.4062 | 0.0921 | |
| GSE45670 | ZBTB4 | 57659 | 225629_s_at | -0.3938 | 0.0103 | |
| GSE53622 | ZBTB4 | 57659 | 39666 | -0.5474 | 0.0000 | |
| GSE53624 | ZBTB4 | 57659 | 39666 | -0.3290 | 0.0011 | |
| GSE63941 | ZBTB4 | 57659 | 225629_s_at | -1.6654 | 0.0006 | |
| GSE77861 | ZBTB4 | 57659 | 225629_s_at | 0.1723 | 0.6316 | |
| GSE97050 | ZBTB4 | 57659 | A_23_P100654 | -1.0118 | 0.1415 | |
| SRP007169 | ZBTB4 | 57659 | RNAseq | -0.4185 | 0.1650 | |
| SRP008496 | ZBTB4 | 57659 | RNAseq | -0.2441 | 0.1793 | |
| SRP064894 | ZBTB4 | 57659 | RNAseq | -0.2593 | 0.0414 | |
| SRP133303 | ZBTB4 | 57659 | RNAseq | -0.5980 | 0.0054 | |
| SRP159526 | ZBTB4 | 57659 | RNAseq | -0.5778 | 0.0084 | |
| SRP193095 | ZBTB4 | 57659 | RNAseq | -0.1074 | 0.3421 | |
| SRP219564 | ZBTB4 | 57659 | RNAseq | -0.3852 | 0.2307 | |
| TCGA | ZBTB4 | 57659 | RNAseq | -0.1955 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZBTB4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB4 | 57659 | 4 | 2 | 24 | |
| GSE20123 | ZBTB4 | 57659 | 4 | 3 | 23 | |
| GSE43470 | ZBTB4 | 57659 | 1 | 4 | 38 | |
| GSE46452 | ZBTB4 | 57659 | 34 | 1 | 24 | |
| GSE47630 | ZBTB4 | 57659 | 7 | 1 | 32 | |
| GSE54993 | ZBTB4 | 57659 | 4 | 3 | 63 | |
| GSE54994 | ZBTB4 | 57659 | 5 | 8 | 40 | |
| GSE60625 | ZBTB4 | 57659 | 4 | 0 | 7 | |
| GSE74703 | ZBTB4 | 57659 | 1 | 2 | 33 | |
| GSE74704 | ZBTB4 | 57659 | 2 | 1 | 17 | |
| TCGA | ZBTB4 | 57659 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of ZBTB4:
Generating mutation plots.
Highly correlated genes for ZBTB4:
Showing top 20/578 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB4 | RBM6 | 0.794775 | 3 | 0 | 3 |
| ZBTB4 | ANK2 | 0.786951 | 3 | 0 | 3 |
| ZBTB4 | SYNC | 0.74957 | 3 | 0 | 3 |
| ZBTB4 | WFDC1 | 0.748133 | 4 | 0 | 4 |
| ZBTB4 | DDR2 | 0.743546 | 4 | 0 | 4 |
| ZBTB4 | FBN1 | 0.741304 | 3 | 0 | 3 |
| ZBTB4 | CHRDL1 | 0.738131 | 3 | 0 | 3 |
| ZBTB4 | NEGR1 | 0.737581 | 4 | 0 | 4 |
| ZBTB4 | DDX42 | 0.735279 | 4 | 0 | 4 |
| ZBTB4 | IL6ST | 0.734325 | 3 | 0 | 3 |
| ZBTB4 | KCTD10 | 0.727967 | 3 | 0 | 3 |
| ZBTB4 | ZEB2 | 0.727588 | 3 | 0 | 3 |
| ZBTB4 | DCHS1 | 0.725187 | 3 | 0 | 3 |
| ZBTB4 | NKTR | 0.722294 | 3 | 0 | 3 |
| ZBTB4 | MYOC | 0.715608 | 3 | 0 | 3 |
| ZBTB4 | UBXN10 | 0.715519 | 3 | 0 | 3 |
| ZBTB4 | ADARB1 | 0.712656 | 3 | 0 | 3 |
| ZBTB4 | ITGA7 | 0.708039 | 3 | 0 | 3 |
| ZBTB4 | PPIG | 0.705789 | 4 | 0 | 4 |
| ZBTB4 | OLFML3 | 0.704812 | 3 | 0 | 3 |
For details and further investigation, click here
