| Full name: Morf4 family associated protein 1 | Alias Symbol: PAM14|PGR1 | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 93621 | HGNC ID: HGNC:24549 | Ensembl Gene: ENSG00000179010 | OMIM ID: 616905 |
| Drug and gene relationship at DGIdb | |||
Expression of MRFAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRFAP1 | 93621 | 226091_s_at | 0.1020 | 0.7852 | |
| GSE26886 | MRFAP1 | 93621 | 226091_s_at | -0.1909 | 0.1269 | |
| GSE45670 | MRFAP1 | 93621 | 226091_s_at | -0.0783 | 0.4922 | |
| GSE53622 | MRFAP1 | 93621 | 73520 | -0.1736 | 0.0016 | |
| GSE53624 | MRFAP1 | 93621 | 73520 | -0.1636 | 0.0459 | |
| GSE63941 | MRFAP1 | 93621 | 226091_s_at | -0.7799 | 0.0055 | |
| GSE77861 | MRFAP1 | 93621 | 226091_s_at | 0.0061 | 0.9727 | |
| GSE97050 | MRFAP1 | 93621 | A_24_P11965 | -0.0076 | 0.9749 | |
| SRP007169 | MRFAP1 | 93621 | RNAseq | 1.2002 | 0.0009 | |
| SRP008496 | MRFAP1 | 93621 | RNAseq | 1.1999 | 0.0001 | |
| SRP064894 | MRFAP1 | 93621 | RNAseq | -0.0821 | 0.6112 | |
| SRP133303 | MRFAP1 | 93621 | RNAseq | 0.0074 | 0.9367 | |
| SRP159526 | MRFAP1 | 93621 | RNAseq | -0.0387 | 0.7943 | |
| SRP193095 | MRFAP1 | 93621 | RNAseq | -0.4646 | 0.0034 | |
| SRP219564 | MRFAP1 | 93621 | RNAseq | -0.0131 | 0.9694 | |
| TCGA | MRFAP1 | 93621 | RNAseq | -0.0682 | 0.1031 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MRFAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRFAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRFAP1 | 93621 | 0 | 18 | 12 | |
| GSE20123 | MRFAP1 | 93621 | 0 | 18 | 12 | |
| GSE43470 | MRFAP1 | 93621 | 0 | 17 | 26 | |
| GSE46452 | MRFAP1 | 93621 | 1 | 36 | 22 | |
| GSE47630 | MRFAP1 | 93621 | 1 | 19 | 20 | |
| GSE54993 | MRFAP1 | 93621 | 10 | 0 | 60 | |
| GSE54994 | MRFAP1 | 93621 | 3 | 12 | 38 | |
| GSE60625 | MRFAP1 | 93621 | 0 | 0 | 11 | |
| GSE74703 | MRFAP1 | 93621 | 0 | 13 | 23 | |
| GSE74704 | MRFAP1 | 93621 | 0 | 10 | 10 | |
| TCGA | MRFAP1 | 93621 | 7 | 48 | 41 |
Total number of gains: 22; Total number of losses: 191; Total Number of normals: 275.
Somatic mutations of MRFAP1:
Generating mutation plots.
Highly correlated genes for MRFAP1:
Showing top 20/324 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRFAP1 | EIF5B | 0.831971 | 3 | 0 | 3 |
| MRFAP1 | TOMM40L | 0.821502 | 3 | 0 | 3 |
| MRFAP1 | WWP1 | 0.814353 | 3 | 0 | 3 |
| MRFAP1 | PPIG | 0.797494 | 3 | 0 | 3 |
| MRFAP1 | NPHP3 | 0.764821 | 3 | 0 | 3 |
| MRFAP1 | UBE2V2 | 0.763942 | 3 | 0 | 3 |
| MRFAP1 | GLRX2 | 0.758964 | 3 | 0 | 3 |
| MRFAP1 | MTRF1L | 0.749788 | 3 | 0 | 3 |
| MRFAP1 | VPS45 | 0.748436 | 3 | 0 | 3 |
| MRFAP1 | KCNJ8 | 0.745943 | 3 | 0 | 3 |
| MRFAP1 | CST7 | 0.74345 | 3 | 0 | 3 |
| MRFAP1 | METTL5 | 0.742077 | 3 | 0 | 3 |
| MRFAP1 | PTPN23 | 0.741454 | 3 | 0 | 3 |
| MRFAP1 | L3MBTL3 | 0.734847 | 3 | 0 | 3 |
| MRFAP1 | EED | 0.73479 | 3 | 0 | 3 |
| MRFAP1 | SIK2 | 0.734788 | 3 | 0 | 3 |
| MRFAP1 | RBM8A | 0.732052 | 3 | 0 | 3 |
| MRFAP1 | PINK1 | 0.731749 | 3 | 0 | 3 |
| MRFAP1 | SLC22A5 | 0.727756 | 3 | 0 | 3 |
| MRFAP1 | MRPS21 | 0.726967 | 3 | 0 | 3 |
For details and further investigation, click here
