REEP4

 

Full name: receptor accessory protein 4 Alias Symbol: FLJ22246|FLJ22277|PP432|Yip2c
Type: protein-coding gene Cytoband: 8p21.3
Entrez ID: 80346 HGNC ID: HGNC:26176 Ensembl Gene: ENSG00000168476 OMIM ID: 609349
Drug and gene relationship at DGIdb

 

Expression of REEP4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 REEP4 80346 218777_at 0.1506 0.7602
GSE20347 REEP4 80346 218777_at 0.0196 0.9160
GSE23400 REEP4 80346 218777_at 0.1190 0.2226
GSE26886 REEP4 80346 218777_at -0.3294 0.0838
GSE29001 REEP4 80346 218777_at -0.0532 0.8663
GSE38129 REEP4 80346 218777_at 0.2232 0.3594
GSE45670 REEP4 80346 218777_at 0.3053 0.0839
GSE53622 REEP4 80346 39153 -0.0341 0.8504
GSE53624 REEP4 80346 39153 -0.3715 0.0001
GSE63941 REEP4 80346 218777_at 1.1610 0.0093
GSE77861 REEP4 80346 218777_at 0.3760 0.1736
GSE97050 REEP4 80346 A_23_P96209 0.5298 0.5560
SRP007169 REEP4 80346 RNAseq -0.8658 0.0557
SRP008496 REEP4 80346 RNAseq -1.1610 0.0008
SRP064894 REEP4 80346 RNAseq -0.0544 0.8486
SRP133303 REEP4 80346 RNAseq -0.4205 0.1109
SRP159526 REEP4 80346 RNAseq -0.3179 0.3499
SRP193095 REEP4 80346 RNAseq -0.3927 0.0471
SRP219564 REEP4 80346 RNAseq -0.5244 0.4317
TCGA REEP4 80346 RNAseq 0.4883 0.0000

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by REEP4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of REEP4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 REEP4 80346 4 10 16
GSE20123 REEP4 80346 4 10 16
GSE43470 REEP4 80346 4 9 30
GSE46452 REEP4 80346 13 13 33
GSE47630 REEP4 80346 10 8 22
GSE54993 REEP4 80346 2 14 54
GSE54994 REEP4 80346 8 18 27
GSE60625 REEP4 80346 3 0 8
GSE74703 REEP4 80346 4 7 25
GSE74704 REEP4 80346 3 7 10
TCGA REEP4 80346 14 43 39

Total number of gains: 69; Total number of losses: 139; Total Number of normals: 280.  

 

Somatic mutations of REEP4:

 

Generating mutation plots.

 

Highly correlated genes for REEP4:

 

Showing top 20/298 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
REEP4SERINC20.729806404
REEP4EME10.719382404
REEP4SPIN40.709873303
REEP4FAM83B0.690396404
REEP4BNC10.687402404
REEP4NRG10.673668404
REEP4EIF1AD0.656172303
REEP4CDCP10.653903605
REEP4SPTBN20.651803303
REEP4B3GNT50.649899605
REEP4RCE10.644991505
REEP4EIF4EBP10.644167705
REEP4NDOR10.642646303
REEP4ACER30.641268303
REEP4S100A110.637575705
REEP4TPD52L10.636322706
REEP4CHPF0.6359403
REEP4SQLE0.635409705
REEP4GGCT0.631573604
REEP4S100A20.628749806

For details and further investigation, click here