| Full name: chondroitin polymerizing factor | Alias Symbol: CSS2|CHSY2 | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 79586 | HGNC ID: HGNC:24291 | Ensembl Gene: ENSG00000123989 | OMIM ID: 610405 |
| Drug and gene relationship at DGIdb | |||
Expression of CHPF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHPF | 79586 | 202175_at | 0.6590 | 0.0523 | |
| GSE20347 | CHPF | 79586 | 202175_at | 0.3809 | 0.0012 | |
| GSE23400 | CHPF | 79586 | 202175_at | 0.4968 | 0.0000 | |
| GSE26886 | CHPF | 79586 | 202175_at | 0.6003 | 0.0006 | |
| GSE29001 | CHPF | 79586 | 202175_at | -0.0685 | 0.7743 | |
| GSE38129 | CHPF | 79586 | 202175_at | 0.5889 | 0.0001 | |
| GSE45670 | CHPF | 79586 | 202175_at | 0.1271 | 0.3089 | |
| GSE53622 | CHPF | 79586 | 22936 | 0.9515 | 0.0000 | |
| GSE53624 | CHPF | 79586 | 22936 | 0.7762 | 0.0000 | |
| GSE63941 | CHPF | 79586 | 202175_at | 0.1487 | 0.7248 | |
| GSE77861 | CHPF | 79586 | 202175_at | 0.4721 | 0.1472 | |
| GSE97050 | CHPF | 79586 | A_33_P3316878 | 0.7900 | 0.0722 | |
| SRP007169 | CHPF | 79586 | RNAseq | 1.3812 | 0.0004 | |
| SRP008496 | CHPF | 79586 | RNAseq | 1.4879 | 0.0000 | |
| SRP064894 | CHPF | 79586 | RNAseq | 1.7055 | 0.0000 | |
| SRP133303 | CHPF | 79586 | RNAseq | 1.8303 | 0.0000 | |
| SRP159526 | CHPF | 79586 | RNAseq | 1.1486 | 0.0000 | |
| SRP193095 | CHPF | 79586 | RNAseq | 1.3224 | 0.0000 | |
| SRP219564 | CHPF | 79586 | RNAseq | 1.5685 | 0.0029 | |
| TCGA | CHPF | 79586 | RNAseq | 0.0990 | 0.0933 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by CHPF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHPF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHPF | 79586 | 2 | 14 | 14 | |
| GSE20123 | CHPF | 79586 | 2 | 13 | 15 | |
| GSE43470 | CHPF | 79586 | 1 | 6 | 36 | |
| GSE46452 | CHPF | 79586 | 0 | 5 | 54 | |
| GSE47630 | CHPF | 79586 | 4 | 5 | 31 | |
| GSE54993 | CHPF | 79586 | 1 | 2 | 67 | |
| GSE54994 | CHPF | 79586 | 8 | 9 | 36 | |
| GSE60625 | CHPF | 79586 | 0 | 3 | 8 | |
| GSE74703 | CHPF | 79586 | 1 | 5 | 30 | |
| GSE74704 | CHPF | 79586 | 2 | 7 | 11 | |
| TCGA | CHPF | 79586 | 13 | 25 | 58 |
Total number of gains: 34; Total number of losses: 94; Total Number of normals: 360.
Somatic mutations of CHPF:
Generating mutation plots.
Highly correlated genes for CHPF:
Showing top 20/1056 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHPF | CNTROB | 0.723426 | 6 | 0 | 6 |
| CHPF | SOCS3 | 0.711788 | 3 | 0 | 3 |
| CHPF | TXNDC12 | 0.70949 | 4 | 0 | 4 |
| CHPF | TTYH3 | 0.707622 | 8 | 0 | 7 |
| CHPF | SLC19A1 | 0.70395 | 3 | 0 | 3 |
| CHPF | POSTN | 0.70044 | 7 | 0 | 6 |
| CHPF | CTF1 | 0.698057 | 3 | 0 | 3 |
| CHPF | BMP8A | 0.693343 | 5 | 0 | 5 |
| CHPF | C16orf74 | 0.687657 | 6 | 0 | 6 |
| CHPF | NSMF | 0.685971 | 3 | 0 | 3 |
| CHPF | KNSTRN | 0.681309 | 4 | 0 | 4 |
| CHPF | CTHRC1 | 0.673934 | 6 | 0 | 4 |
| CHPF | NAV1 | 0.670891 | 5 | 0 | 4 |
| CHPF | ADAMTS12 | 0.670632 | 8 | 0 | 6 |
| CHPF | P4HA2 | 0.66696 | 3 | 0 | 3 |
| CHPF | KCNS2 | 0.665321 | 3 | 0 | 3 |
| CHPF | PLBD2 | 0.661197 | 6 | 0 | 5 |
| CHPF | ITGB4 | 0.659628 | 10 | 0 | 9 |
| CHPF | ADAMTS2 | 0.659594 | 7 | 0 | 5 |
| CHPF | SERPINE1 | 0.659334 | 9 | 0 | 8 |
For details and further investigation, click here
