| Full name: riboflavin kinase | Alias Symbol: FLJ11149|RIFK | ||
| Type: protein-coding gene | Cytoband: 9q21.13 | ||
| Entrez ID: 55312 | HGNC ID: HGNC:30324 | Ensembl Gene: ENSG00000135002 | OMIM ID: 613010 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RFK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFK | 55312 | 203224_at | -0.1030 | 0.7846 | |
| GSE20347 | RFK | 55312 | 203225_s_at | -0.5930 | 0.0540 | |
| GSE23400 | RFK | 55312 | 203225_s_at | -0.3966 | 0.0000 | |
| GSE26886 | RFK | 55312 | 203224_at | -1.0264 | 0.0017 | |
| GSE29001 | RFK | 55312 | 203224_at | -0.2920 | 0.3750 | |
| GSE38129 | RFK | 55312 | 203224_at | -0.4100 | 0.0388 | |
| GSE45670 | RFK | 55312 | 203224_at | -0.5002 | 0.0053 | |
| GSE53622 | RFK | 55312 | 29091 | -0.7830 | 0.0000 | |
| GSE53624 | RFK | 55312 | 29091 | -0.7176 | 0.0000 | |
| GSE63941 | RFK | 55312 | 203224_at | -1.1045 | 0.0748 | |
| GSE77861 | RFK | 55312 | 203224_at | -0.6133 | 0.1881 | |
| GSE97050 | RFK | 55312 | A_23_P216708 | -0.1307 | 0.6270 | |
| SRP007169 | RFK | 55312 | RNAseq | -2.0824 | 0.0003 | |
| SRP008496 | RFK | 55312 | RNAseq | -1.8748 | 0.0000 | |
| SRP064894 | RFK | 55312 | RNAseq | -0.9476 | 0.0001 | |
| SRP133303 | RFK | 55312 | RNAseq | -0.3338 | 0.0876 | |
| SRP159526 | RFK | 55312 | RNAseq | -0.6051 | 0.0105 | |
| SRP193095 | RFK | 55312 | RNAseq | -1.0552 | 0.0000 | |
| SRP219564 | RFK | 55312 | RNAseq | -0.3725 | 0.1997 | |
| TCGA | RFK | 55312 | RNAseq | -0.3686 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RFK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFK | 55312 | 6 | 10 | 14 | |
| GSE20123 | RFK | 55312 | 6 | 10 | 14 | |
| GSE43470 | RFK | 55312 | 6 | 5 | 32 | |
| GSE46452 | RFK | 55312 | 6 | 14 | 39 | |
| GSE47630 | RFK | 55312 | 1 | 18 | 21 | |
| GSE54993 | RFK | 55312 | 4 | 2 | 64 | |
| GSE54994 | RFK | 55312 | 4 | 12 | 37 | |
| GSE60625 | RFK | 55312 | 0 | 0 | 11 | |
| GSE74703 | RFK | 55312 | 5 | 4 | 27 | |
| GSE74704 | RFK | 55312 | 3 | 7 | 10 | |
| TCGA | RFK | 55312 | 18 | 28 | 50 |
Total number of gains: 59; Total number of losses: 110; Total Number of normals: 319.
Somatic mutations of RFK:
Generating mutation plots.
Highly correlated genes for RFK:
Showing top 20/667 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFK | MNS1 | 0.776627 | 3 | 0 | 3 |
| RFK | ZNF92 | 0.775979 | 3 | 0 | 3 |
| RFK | USP24 | 0.738019 | 3 | 0 | 3 |
| RFK | ZDHHC21 | 0.727717 | 3 | 0 | 3 |
| RFK | GRPEL1 | 0.713767 | 3 | 0 | 3 |
| RFK | MKKS | 0.713739 | 3 | 0 | 3 |
| RFK | TMEM186 | 0.706031 | 3 | 0 | 3 |
| RFK | DLL1 | 0.704496 | 3 | 0 | 3 |
| RFK | GPCPD1 | 0.698292 | 3 | 0 | 3 |
| RFK | AKIP1 | 0.697921 | 3 | 0 | 3 |
| RFK | FBXW5 | 0.69377 | 3 | 0 | 3 |
| RFK | ANO8 | 0.688124 | 3 | 0 | 3 |
| RFK | RBM20 | 0.685965 | 3 | 0 | 3 |
| RFK | ZNF555 | 0.678231 | 5 | 0 | 5 |
| RFK | HMGN1 | 0.676291 | 3 | 0 | 3 |
| RFK | SMU1 | 0.672226 | 4 | 0 | 3 |
| RFK | ZNF844 | 0.669816 | 6 | 0 | 6 |
| RFK | ZFP3 | 0.66819 | 3 | 0 | 3 |
| RFK | PCGF3 | 0.667784 | 3 | 0 | 3 |
| RFK | NDUFS3 | 0.662902 | 4 | 0 | 3 |
For details and further investigation, click here
