| Full name: glycerophosphocholine phosphodiesterase 1 | Alias Symbol: KIAA1434|GDE5|GDPD6 | ||
| Type: protein-coding gene | Cytoband: 20p12.3 | ||
| Entrez ID: 56261 | HGNC ID: HGNC:26957 | Ensembl Gene: ENSG00000125772 | OMIM ID: 614124 |
| Drug and gene relationship at DGIdb | |||
Expression of GPCPD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPCPD1 | 56261 | 224826_at | -0.3584 | 0.5150 | |
| GSE26886 | GPCPD1 | 56261 | 224826_at | -1.2310 | 0.0005 | |
| GSE45670 | GPCPD1 | 56261 | 224826_at | 0.3413 | 0.2424 | |
| GSE53622 | GPCPD1 | 56261 | 7125 | -0.3975 | 0.0000 | |
| GSE53624 | GPCPD1 | 56261 | 7125 | -0.2641 | 0.0036 | |
| GSE63941 | GPCPD1 | 56261 | 224826_at | -2.1759 | 0.0429 | |
| GSE77861 | GPCPD1 | 56261 | 224826_at | -0.1953 | 0.6536 | |
| GSE97050 | GPCPD1 | 56261 | A_23_P91350 | -0.1423 | 0.8339 | |
| SRP007169 | GPCPD1 | 56261 | RNAseq | -1.9269 | 0.0000 | |
| SRP008496 | GPCPD1 | 56261 | RNAseq | -1.4755 | 0.0000 | |
| SRP064894 | GPCPD1 | 56261 | RNAseq | -0.1891 | 0.4797 | |
| SRP133303 | GPCPD1 | 56261 | RNAseq | 0.1750 | 0.2544 | |
| SRP159526 | GPCPD1 | 56261 | RNAseq | -1.3132 | 0.0000 | |
| SRP193095 | GPCPD1 | 56261 | RNAseq | -0.5164 | 0.0017 | |
| SRP219564 | GPCPD1 | 56261 | RNAseq | 0.2349 | 0.4693 | |
| TCGA | GPCPD1 | 56261 | RNAseq | -0.0644 | 0.4734 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by GPCPD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPCPD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPCPD1 | 56261 | 10 | 3 | 17 | |
| GSE20123 | GPCPD1 | 56261 | 10 | 3 | 17 | |
| GSE43470 | GPCPD1 | 56261 | 10 | 1 | 32 | |
| GSE46452 | GPCPD1 | 56261 | 26 | 1 | 32 | |
| GSE47630 | GPCPD1 | 56261 | 18 | 4 | 18 | |
| GSE54993 | GPCPD1 | 56261 | 2 | 14 | 54 | |
| GSE54994 | GPCPD1 | 56261 | 25 | 2 | 26 | |
| GSE60625 | GPCPD1 | 56261 | 0 | 0 | 11 | |
| GSE74703 | GPCPD1 | 56261 | 9 | 1 | 26 | |
| GSE74704 | GPCPD1 | 56261 | 5 | 1 | 14 | |
| TCGA | GPCPD1 | 56261 | 40 | 11 | 45 |
Total number of gains: 155; Total number of losses: 41; Total Number of normals: 292.
Somatic mutations of GPCPD1:
Generating mutation plots.
Highly correlated genes for GPCPD1:
Showing top 20/304 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPCPD1 | IMPA1 | 0.787657 | 3 | 0 | 3 |
| GPCPD1 | ZNF346 | 0.775722 | 3 | 0 | 3 |
| GPCPD1 | ATG12 | 0.75929 | 3 | 0 | 3 |
| GPCPD1 | RND3 | 0.757417 | 3 | 0 | 3 |
| GPCPD1 | PFKP | 0.751447 | 3 | 0 | 3 |
| GPCPD1 | RHBDF1 | 0.749233 | 3 | 0 | 3 |
| GPCPD1 | FBXW7 | 0.737504 | 4 | 0 | 4 |
| GPCPD1 | LAMTOR3 | 0.736949 | 3 | 0 | 3 |
| GPCPD1 | APIP | 0.736308 | 3 | 0 | 3 |
| GPCPD1 | TXNL1 | 0.734077 | 3 | 0 | 3 |
| GPCPD1 | TMUB2 | 0.72989 | 3 | 0 | 3 |
| GPCPD1 | PHF3 | 0.729669 | 3 | 0 | 3 |
| GPCPD1 | THAP2 | 0.729333 | 3 | 0 | 3 |
| GPCPD1 | KCTD6 | 0.722811 | 4 | 0 | 4 |
| GPCPD1 | ACADVL | 0.719532 | 3 | 0 | 3 |
| GPCPD1 | PGK1 | 0.715043 | 3 | 0 | 3 |
| GPCPD1 | STX6 | 0.714175 | 3 | 0 | 3 |
| GPCPD1 | SLC46A2 | 0.713245 | 3 | 0 | 3 |
| GPCPD1 | AK4 | 0.709976 | 3 | 0 | 3 |
| GPCPD1 | RNF11 | 0.708233 | 3 | 0 | 3 |
For details and further investigation, click here
