| Full name: GrpE like 1, mitochondrial | Alias Symbol: FLJ25609|GrpE|hMGE | ||
| Type: protein-coding gene | Cytoband: 4p16.1 | ||
| Entrez ID: 80273 | HGNC ID: HGNC:19696 | Ensembl Gene: ENSG00000109519 | OMIM ID: 606173 |
| Drug and gene relationship at DGIdb | |||
Expression of GRPEL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRPEL1 | 80273 | 212432_at | 0.2510 | 0.5338 | |
| GSE20347 | GRPEL1 | 80273 | 212432_at | -0.3563 | 0.0301 | |
| GSE23400 | GRPEL1 | 80273 | 212432_at | 0.0412 | 0.6400 | |
| GSE26886 | GRPEL1 | 80273 | 212432_at | -0.9463 | 0.0000 | |
| GSE29001 | GRPEL1 | 80273 | 212432_at | -0.2270 | 0.4811 | |
| GSE38129 | GRPEL1 | 80273 | 212432_at | -0.0215 | 0.8980 | |
| GSE45670 | GRPEL1 | 80273 | 212432_at | 0.1365 | 0.4294 | |
| GSE53622 | GRPEL1 | 80273 | 7715 | 0.1110 | 0.1283 | |
| GSE53624 | GRPEL1 | 80273 | 7715 | 0.0550 | 0.4563 | |
| GSE63941 | GRPEL1 | 80273 | 212432_at | 0.5276 | 0.2218 | |
| GSE77861 | GRPEL1 | 80273 | 212434_at | 0.1356 | 0.6758 | |
| GSE97050 | GRPEL1 | 80273 | A_33_P3522525 | -0.0897 | 0.7937 | |
| SRP007169 | GRPEL1 | 80273 | RNAseq | -0.1213 | 0.7649 | |
| SRP008496 | GRPEL1 | 80273 | RNAseq | 0.0051 | 0.9865 | |
| SRP064894 | GRPEL1 | 80273 | RNAseq | -0.0870 | 0.6701 | |
| SRP133303 | GRPEL1 | 80273 | RNAseq | 0.0300 | 0.7964 | |
| SRP159526 | GRPEL1 | 80273 | RNAseq | -0.2901 | 0.2858 | |
| SRP193095 | GRPEL1 | 80273 | RNAseq | -0.3870 | 0.0010 | |
| SRP219564 | GRPEL1 | 80273 | RNAseq | -0.1883 | 0.6410 | |
| TCGA | GRPEL1 | 80273 | RNAseq | -0.0511 | 0.3812 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GRPEL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRPEL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRPEL1 | 80273 | 0 | 18 | 12 | |
| GSE20123 | GRPEL1 | 80273 | 0 | 18 | 12 | |
| GSE43470 | GRPEL1 | 80273 | 0 | 17 | 26 | |
| GSE46452 | GRPEL1 | 80273 | 1 | 36 | 22 | |
| GSE47630 | GRPEL1 | 80273 | 1 | 19 | 20 | |
| GSE54993 | GRPEL1 | 80273 | 10 | 0 | 60 | |
| GSE54994 | GRPEL1 | 80273 | 3 | 12 | 38 | |
| GSE60625 | GRPEL1 | 80273 | 0 | 0 | 11 | |
| GSE74703 | GRPEL1 | 80273 | 0 | 13 | 23 | |
| GSE74704 | GRPEL1 | 80273 | 0 | 10 | 10 | |
| TCGA | GRPEL1 | 80273 | 7 | 48 | 41 |
Total number of gains: 22; Total number of losses: 191; Total Number of normals: 275.
Somatic mutations of GRPEL1:
Generating mutation plots.
Highly correlated genes for GRPEL1:
Showing top 20/308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRPEL1 | PPP4R2 | 0.815292 | 3 | 0 | 3 |
| GRPEL1 | OSBPL2 | 0.787695 | 3 | 0 | 3 |
| GRPEL1 | COMT | 0.780263 | 3 | 0 | 3 |
| GRPEL1 | AMPD3 | 0.753141 | 3 | 0 | 3 |
| GRPEL1 | MZT1 | 0.74946 | 4 | 0 | 4 |
| GRPEL1 | TTC39B | 0.748326 | 3 | 0 | 3 |
| GRPEL1 | MAP4K5 | 0.740017 | 3 | 0 | 3 |
| GRPEL1 | FDPS | 0.715808 | 5 | 0 | 5 |
| GRPEL1 | RFK | 0.713767 | 3 | 0 | 3 |
| GRPEL1 | AGAP4 | 0.711522 | 3 | 0 | 3 |
| GRPEL1 | MST1R | 0.71083 | 3 | 0 | 3 |
| GRPEL1 | SRSF10 | 0.701873 | 3 | 0 | 3 |
| GRPEL1 | VPS37A | 0.701443 | 3 | 0 | 3 |
| GRPEL1 | SLC25A30 | 0.700311 | 3 | 0 | 3 |
| GRPEL1 | IPMK | 0.699557 | 4 | 0 | 3 |
| GRPEL1 | C5orf51 | 0.696809 | 3 | 0 | 3 |
| GRPEL1 | PDE12 | 0.695285 | 4 | 0 | 4 |
| GRPEL1 | CHD1 | 0.68981 | 3 | 0 | 3 |
| GRPEL1 | INTS12 | 0.688323 | 3 | 0 | 3 |
| GRPEL1 | CNN3 | 0.687925 | 3 | 0 | 3 |
For details and further investigation, click here
