| Full name: rhomboid like 3 | Alias Symbol: VRHO | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 162494 | HGNC ID: HGNC:16502 | Ensembl Gene: ENSG00000141314 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RHBDL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDL3 | 162494 | 230755_at | -0.0134 | 0.9830 | |
| GSE26886 | RHBDL3 | 162494 | 233232_at | -0.0608 | 0.6029 | |
| GSE45670 | RHBDL3 | 162494 | 230755_at | -0.0331 | 0.8214 | |
| GSE53622 | RHBDL3 | 162494 | 105593 | 0.3080 | 0.2769 | |
| GSE53624 | RHBDL3 | 162494 | 105593 | 0.2804 | 0.0954 | |
| GSE63941 | RHBDL3 | 162494 | 230755_at | 0.3163 | 0.2732 | |
| GSE77861 | RHBDL3 | 162494 | 233409_at | -0.1561 | 0.1343 | |
| SRP133303 | RHBDL3 | 162494 | RNAseq | 0.8111 | 0.0595 | |
| SRP159526 | RHBDL3 | 162494 | RNAseq | 1.1882 | 0.0344 | |
| SRP219564 | RHBDL3 | 162494 | RNAseq | 0.7539 | 0.1888 | |
| TCGA | RHBDL3 | 162494 | RNAseq | 0.0188 | 0.9512 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RHBDL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHBDL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDL3 | 162494 | 9 | 2 | 19 | |
| GSE20123 | RHBDL3 | 162494 | 8 | 2 | 20 | |
| GSE43470 | RHBDL3 | 162494 | 1 | 1 | 41 | |
| GSE46452 | RHBDL3 | 162494 | 33 | 1 | 25 | |
| GSE47630 | RHBDL3 | 162494 | 7 | 1 | 32 | |
| GSE54993 | RHBDL3 | 162494 | 3 | 3 | 64 | |
| GSE54994 | RHBDL3 | 162494 | 7 | 6 | 40 | |
| GSE60625 | RHBDL3 | 162494 | 4 | 0 | 7 | |
| GSE74703 | RHBDL3 | 162494 | 1 | 1 | 34 | |
| GSE74704 | RHBDL3 | 162494 | 6 | 2 | 12 | |
| TCGA | RHBDL3 | 162494 | 19 | 10 | 67 |
Total number of gains: 98; Total number of losses: 29; Total Number of normals: 361.
Somatic mutations of RHBDL3:
Generating mutation plots.
Highly correlated genes for RHBDL3:
Showing all 20 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDL3 | DOC2A | 0.694294 | 3 | 0 | 3 |
| RHBDL3 | SPATA24 | 0.673083 | 3 | 0 | 3 |
| RHBDL3 | WNT6 | 0.642136 | 3 | 0 | 3 |
| RHBDL3 | SNAI3 | 0.619025 | 3 | 0 | 3 |
| RHBDL3 | KCNH3 | 0.606221 | 3 | 0 | 3 |
| RHBDL3 | CD5L | 0.603021 | 3 | 0 | 3 |
| RHBDL3 | CCDC157 | 0.601397 | 3 | 0 | 3 |
| RHBDL3 | SIX3 | 0.599182 | 4 | 0 | 3 |
| RHBDL3 | MAP3K19 | 0.592871 | 4 | 0 | 3 |
| RHBDL3 | MGAT3 | 0.566679 | 5 | 0 | 4 |
| RHBDL3 | FOXP3 | 0.566609 | 3 | 0 | 3 |
| RHBDL3 | SYNGAP1 | 0.556391 | 3 | 0 | 3 |
| RHBDL3 | ATN1 | 0.55445 | 6 | 0 | 3 |
| RHBDL3 | RD3 | 0.553207 | 4 | 0 | 3 |
| RHBDL3 | UBXN11 | 0.550507 | 3 | 0 | 3 |
| RHBDL3 | MAPK12 | 0.549514 | 3 | 0 | 3 |
| RHBDL3 | VWA5B2 | 0.540462 | 4 | 0 | 3 |
| RHBDL3 | LINC01119 | 0.529318 | 4 | 0 | 3 |
| RHBDL3 | ACACB | 0.521331 | 5 | 0 | 3 |
| RHBDL3 | PRAMEF11 | 0.503142 | 4 | 0 | 3 |
For details and further investigation, click here
