| Full name: atrophin 1 | Alias Symbol: B37 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 1822 | HGNC ID: HGNC:3033 | Ensembl Gene: ENSG00000111676 | OMIM ID: 607462 |
| Drug and gene relationship at DGIdb | |||
Expression of ATN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATN1 | 1822 | 40489_at | 0.3164 | 0.5087 | |
| GSE20347 | ATN1 | 1822 | 40489_at | 0.3137 | 0.0088 | |
| GSE23400 | ATN1 | 1822 | 40489_at | 0.1202 | 0.0270 | |
| GSE26886 | ATN1 | 1822 | 40489_at | 0.0487 | 0.6864 | |
| GSE29001 | ATN1 | 1822 | 40489_at | -0.1492 | 0.1881 | |
| GSE38129 | ATN1 | 1822 | 40489_at | 0.0487 | 0.7769 | |
| GSE45670 | ATN1 | 1822 | 1555754_s_at | -0.0179 | 0.8937 | |
| GSE53622 | ATN1 | 1822 | 40687 | 0.1630 | 0.0554 | |
| GSE53624 | ATN1 | 1822 | 40687 | 0.4832 | 0.0000 | |
| GSE63941 | ATN1 | 1822 | 40489_at | 1.1007 | 0.0006 | |
| GSE77861 | ATN1 | 1822 | 40489_at | -0.0049 | 0.9794 | |
| GSE97050 | ATN1 | 1822 | A_23_P13885 | -0.0933 | 0.7411 | |
| SRP007169 | ATN1 | 1822 | RNAseq | 0.6201 | 0.0889 | |
| SRP008496 | ATN1 | 1822 | RNAseq | 0.8290 | 0.0019 | |
| SRP064894 | ATN1 | 1822 | RNAseq | 0.4750 | 0.0373 | |
| SRP133303 | ATN1 | 1822 | RNAseq | 0.2200 | 0.2759 | |
| SRP159526 | ATN1 | 1822 | RNAseq | 0.8514 | 0.0096 | |
| SRP193095 | ATN1 | 1822 | RNAseq | 0.9571 | 0.0000 | |
| SRP219564 | ATN1 | 1822 | RNAseq | 0.0082 | 0.9828 | |
| TCGA | ATN1 | 1822 | RNAseq | -0.0297 | 0.4898 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ATN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATN1 | 1822 | 9 | 3 | 18 | |
| GSE20123 | ATN1 | 1822 | 9 | 3 | 18 | |
| GSE43470 | ATN1 | 1822 | 8 | 3 | 32 | |
| GSE46452 | ATN1 | 1822 | 10 | 1 | 48 | |
| GSE47630 | ATN1 | 1822 | 12 | 2 | 26 | |
| GSE54993 | ATN1 | 1822 | 1 | 10 | 59 | |
| GSE54994 | ATN1 | 1822 | 10 | 2 | 41 | |
| GSE60625 | ATN1 | 1822 | 0 | 1 | 10 | |
| GSE74703 | ATN1 | 1822 | 7 | 2 | 27 | |
| GSE74704 | ATN1 | 1822 | 5 | 3 | 12 | |
| TCGA | ATN1 | 1822 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 36; Total Number of normals: 341.
Somatic mutations of ATN1:
Generating mutation plots.
Highly correlated genes for ATN1:
Showing top 20/715 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATN1 | HES4 | 0.815498 | 3 | 0 | 3 |
| ATN1 | ZNF683 | 0.792158 | 3 | 0 | 3 |
| ATN1 | ZC3H18 | 0.781827 | 3 | 0 | 3 |
| ATN1 | KIR2DL5A | 0.737173 | 5 | 0 | 5 |
| ATN1 | ZMAT4 | 0.736513 | 3 | 0 | 3 |
| ATN1 | APOB | 0.7341 | 3 | 0 | 3 |
| ATN1 | TBC1D25 | 0.733017 | 3 | 0 | 3 |
| ATN1 | GPR4 | 0.720219 | 4 | 0 | 4 |
| ATN1 | RARG | 0.720119 | 3 | 0 | 3 |
| ATN1 | KHDRBS2 | 0.71866 | 4 | 0 | 4 |
| ATN1 | GJC2 | 0.712693 | 3 | 0 | 3 |
| ATN1 | GH2 | 0.709195 | 4 | 0 | 3 |
| ATN1 | ATOH1 | 0.707513 | 4 | 0 | 4 |
| ATN1 | XPNPEP2 | 0.707425 | 3 | 0 | 3 |
| ATN1 | GABRB2 | 0.707396 | 5 | 0 | 5 |
| ATN1 | MUL1 | 0.706002 | 3 | 0 | 3 |
| ATN1 | PPP1R15A | 0.705383 | 3 | 0 | 3 |
| ATN1 | AP4S1 | 0.700299 | 3 | 0 | 3 |
| ATN1 | HAND2 | 0.698074 | 3 | 0 | 3 |
| ATN1 | SGCA | 0.697701 | 3 | 0 | 3 |
For details and further investigation, click here
